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You searched for: Subject "sporozoites" Remove constraint Subject: "sporozoites"
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1. A new species of Isospora (Apicomplexa: Eimeriidae) from the yellow warbler, Setophaga petechia (L.) (Passeriformes: Parulidae: Parulinae), in Oklahoma, USA

Author:
Chris T. McAllister; John A. Hnida
Source:
Current research in parasitology and vector-borne diseases 2022 v.2 pp. 100096
ISSN:
2667-114X
Subject:
sporozoites,   etc   ; Isospora; Setophaga; new species; parasitology; research; Brazil; Costa Rica; Mexico; Oklahoma;     Show all 10 Subjects
Abstract:
... Isospora fitzpatricki n. sp. is described from a yellow warbler, Setophaga petechia (L.), from McCurtain County, Oklahoma, USA. Oöcysts of the new species are subspheroidal to ovoidal with a smooth bi-layered wall, measure (L × W) 24.2 × 20.4 μm, and have a length/width (L/W) ratio of 1.2; a micropyle and oöcyst residuum are both absent, but polar granule(s) are present. Sporocysts are ovoidal to ...
DOI:
10.1016/j.crpvbd.2022.100096

2. Strategies for conducting Anopheles stephensi surveys in non-endemic areas

Author:
Ayman Ahmed; Seth R. Irish; Sarah Zohdy; Melissa Yoshimizu; Fitsum G. Tadesse
Source:
Acta tropica 2022 v.236 pp. 106671
ISSN:
0001-706X
Subject:
sporozoites,   etc   ; Anopheles stephensi; ecology; monitoring; mosquito vectors; stakeholders; Asia; Djibouti; Ethiopia; Somalia; Sudan;     Show all 11 Subjects
Abstract:
... Anopheles stephensi, a malaria vector species previously only known from Asia, was first detected in Africa in Djibouti in 2012, has been subsequently collected in Ethiopia, Sudan, and Somalia, and may be spreading further. Countries may wish to implement mosquito surveys to determine if An. stephensi is present, or to determine the extent of its distribution, if present. Furthermore, mosquito sur ...
DOI:
10.1016/j.actatropica.2022.106671

3. Adeno-associated virus-based malaria booster vaccine following attenuated replication-competent vaccinia virus LC16m8Δ priming

Author:
Ammar A. Hasyim; Mitsuhiro Iyori; Tetsushi Mizuno; Yu-ichi Abe; Iroha Yamagoshi; Yenni Yusuf; Intan Syafira; Akihiko Sakamoto; Yutaro Yamamoto; Hiroaki Mizukami; Hisatoshi Shida; Shigeto Yoshida
Source:
Parasitology international 2023 v.92 pp. 102652
ISSN:
1383-5769
Subject:
sporozoites,   etc   ; Dependoparvovirus; Plasmodium falciparum; Vaccinia virus; animal models; genes; immunization; malaria; malaria vaccines; parasitology; serotypes;     Show all 11 Subjects
Abstract:
... We previously demonstrated that boosting with adeno-associated virus (AAV) type 1 (AAV1) can induce highly effective and long-lasting protective immune responses against malaria parasites when combined with replication-deficient adenovirus priming in a rodent model. In the present study, we compared the efficacy of two different AAV serotypes, AAV1 and AAV5, as malaria booster vaccines following p ...
DOI:
10.1016/j.parint.2022.102652

4. Persistently high proportions of plasmodium-infected Anopheles funestus mosquitoes in two villages in the Kilombero valley, South-Eastern Tanzania

Author:
Salum A. Mapua; Emmanuel E. Hape; Japhet Kihonda; Hamis Bwanary; Khamis Kifungo; Masoud Kilalangongono; Emmanuel W. Kaindoa; Halfan S. Ngowo; Fredros O. Okumu
Source:
Parasite epidemiology and control 2022 v.18 pp. e00264
ISSN:
2405-6731
Subject:
sporozoites,   etc   ; Anopheles arabiensis; Anopheles funestus; Plasmodium; disease transmission; insecticide application; malaria; mosquito vectors; parasites; Tanzania;     Show all 10 Subjects
Abstract:
... In south-eastern Tanzania where insecticide-treated nets have been widely used for >20 years, malaria transmission has greatly reduced but remains highly heterogenous over small distances. This study investigated the seasonal prevalence of Plasmodium sporozoite infections in the two main malaria vector species, Anopheles funestus and Anopheles arabiensis for 34 months, starting January 2018 to Nov ...
DOI:
10.1016/j.parepi.2022.e00264

5. Live attenuated vaccines, a favorable strategy to provide long-term immunity against protozoan diseases

Author:
Jose C. Solana; Javier Moreno; Salvador Iborra; Manuel Soto; Jose M. Requena
Source:
Trends in parasitology 2022 v.38 no.4 pp. 316-334
ISSN:
1471-4922
Subject:
sporozoites,   etc   ; Chagas disease; Protozoa; biosafety; clinical examination; immunity; irradiation; leishmaniasis; live vaccines; malaria; parasitology; sustainable development;     Show all 12 Subjects
Abstract:
... The control of diseases caused by protozoan parasites is one of the United Nations' Sustainable Development Goals. In recent years much research effort has gone into developing a new generation of live attenuated vaccines (LAVs) against malaria, Chagas disease and leishmaniasis. However, there is a bottleneck related to their biosafety, production, and distribution that slows downs further develop ...
DOI:
10.1016/j.pt.2021.11.004

6. Targeting APC-Host Microbe interactions 1Antigen presentation for liver-stage immunity to Plasmodium Infection

Author:
William Heath
Source:
Molecular immunology 2022 v.150 no. pp. -
ISSN:
0161-5890
Subject:
sporozoites,   etc   ; Anopheles; CD8-positive T-lymphocytes; Plasmodium; antibodies; females; hepatocytes; immunity; liver; malaria; merozoites; vaccination; vaccines;     Show all 13 Subjects
Abstract:
... Malaria is a highly prevalent parasitic disease, accounting for approximately 216 million infections and 445,000 deaths per annum. Disease is caused by Plasmodium spp. and is transmitted via female Anopheles mosquitoes. Following a bite from an infected mosquito, immature parasites (sporozoites) are released into the skin and migrate via the blood to the liver where they asymptomatically infect he ...
DOI:
10.1016/j.molimm.2022.05.067

7. Effects of host vimentin on Eimeria tenella sporozoite invasion

Author:
Zhan Liu; Xiangfei Geng; Qiping Zhao; Shunhai Zhu; Hongyu Han; Yu Yu; Wenhao Huang; Yawen Yao; Bing Huang; Hui Dong
Source:
Parasites & vectors 2022 v.15 no.1 pp. 8
ISSN:
1756-3305
Subject:
sporozoites,   etc   ; Eimeria tenella; chickens; coccidiosis; financial economics; fluorescent antibody technique; industry; phosphorylation; polyclonal antibodies; proteomics; vimentin;     Show all 11 Subjects
Abstract:
... BACKGROUND: Chicken coccidiosis is a parasitic disease caused by Eimeria of Apicomplexa, which has caused great economic loss to the poultry breeding industry. Host vimentin is a key protein in the process of infection of many pathogens. In an earlier phosphorylation proteomics study, we found that the phosphorylation level of host vimentin was significantly regulated after Eimeria tenella sporozo ...
DOI:
10.1186/s13071-021-05107-4

8. TSS-seq of Toxoplasma gondii sporozoites revealed a novel motif in stage-specific promoters

Author:
Taishi Kidaka; Tatsuki Sugi; Kyoko Hayashida; Yutaka Suzuki; Xuenan Xuan; Jitender P. Dubey; Junya Yamagishi
Source:
Infection, genetics, and evolution 2022 v.98 pp. 105213
ISSN:
1567-1348
Subject:
sporozoites,   etc   ; Plasmodium berghei; Protozoa; Toxoplasma gondii; bradyzoites; evolution; gene expression; infection; sequence analysis; tachyzoites; transcription (genetics); transcriptome;     Show all 12 Subjects
Abstract:
... Toxoplasma gondii is one of the most common zoonotic protozoan parasites. It has three major infectious stages: rapidly multiplying tachyzoites (Tz), slowly replicating bradyzoites (Bz) and a resting/free-living stage, sporozoites (Sz). The regulatory mechanisms governing stage-specific gene expression are not fully understood. Few transcriptional start sites (TSS) are known for Sz. In this study, ...
DOI:
10.1016/j.meegid.2022.105213

9. The Effect of Short-Chain Fatty Acids on Growth of Cryptosporidium parvum In Vitro

Author:
Aidan P. Keelaghan; Raheela Charania; Jan R. Mead
Source:
Microorganisms 2022 v.10 no.9 pp. -
ISSN:
2076-2607
Subject:
sporozoites,   etc   ; Cryptosporidium parvum; acetates; adenocarcinoma; apoptosis; butyrates; cytokines; fluorescence microscopes; growth retardation; humans; monoclonal antibodies; oocysts; pathogenicity; propionic acid;     Show all 14 Subjects
Abstract:
... In a previous study, we observed an increase in the severity of cryptosporidial infection corresponding to decreased levels of short-chain fatty acids (SCFAs). Therefore, we decided to examine the effect of SCFAs on Cryptosporidium growth in human ileocecal adenocarcinoma (HTC-8) cells. HTC-8 cells were infected with 1 × 10⁵ C. parvum oocysts. After 48 h of incubation with selected SCFAs, cells we ...
DOI:
10.3390/microorganisms10091822

10. Mitochondrial Spermidine Synthase is Essential for Blood-stage growth of the Malaria Parasite

Author:
Mohd Kamil; Umit Y. Kina; Gozde Deveci; Sevim N. Akyuz; Ilknur Yilmaz; Ahmed S.I. Aly
Source:
Microbiological research 2022 v.265 pp. 127181
ISSN:
0944-5013
Subject:
sporozoites,   etc   ; Plasmodium falciparum; Plasmodium yoelii; Trypanosoma brucei; drugs; fluorescence; genes; malaria; mitochondria; parasites; putrescine; research; spermidine; spermidine synthase; spermine;     Show all 15 Subjects
Abstract:
... Positively-charged polyamines are essential molecules for the replication of eukaryotic cells and are particularly important for the rapid proliferation of parasitic protozoa and cancer cells. Unlike in Trypanosoma brucei, the inhibition of the synthesis of intermediate polyamine Putrescine caused only partial defect in malaria parasite blood-stage growth. In contrast, reducing the intracellular c ...
DOI:
10.1016/j.micres.2022.127181

11. Vector Competence and the Susceptibility of Anopheles pullus and Anopheles belenrae to Plasmodium vivax-Infected Blood From Thai Patients

Author:
Ratawan Ubalee; Heung-Chul Kim; Siriporn Phasomkusolsil; Jaruwan Tawong; Ratree Takhampunya; Amnart Kayha; Suparat Chairuksa; Waranya Buadok; Vichit Phunkitchar; Betty K. Poole-Smith; Silas A. Davidson; Won-Ja Lee; Terry A. Klein
Source:
Journal of medical entomology 2022 v.59 no.3 pp. 1047-1052
ISSN:
0022-2585
Subject:
sporozoites,   etc   ; Anopheles hyrcanus; Anopheles pullus; Anopheles sinensis; blood; geographical distribution; malaria; medical entomology; oocysts; salivary glands; vector competence; South Korea;     Show all 12 Subjects
Abstract:
... There are eight Anopheles spp. present in the Republic of Korea (ROK), including five members of the Anopheles Hyrcanus Group that cannot be identified using current morphological methods. The vector competence of only Anopheles sinensis s.s., An. lesteri, and An. kleini have been investigated. As the geographical distribution of Anopheles spp. varies in the ROK, determining the relative vector co ...
DOI:
10.1093/jme/tjab226

12. A new Eimeria coccidian species (Apicomplexa: Eimeriidae) from Père David’s deer (Elaphurus davidianus Milne-Edwards, 1866) in Dafeng Milu National Nature Reserve in Jiangsu Province, eastern China

Author:
Weimin Cai; Zeyang Suding; Lele Wang; Zhaofeng Hou; Dandan Liu; Siyang Huang; Jinjun Xu; Jianping Tao
Source:
BMC veterinary research 2022 v.18 no.1 pp. 213
ISSN:
1746-6148
Subject:
sporozoites,   etc   ; Eimeria; Elaphurus davidianus; coccidiosis; conservation areas; death; endangered species; intestines; new species; oocysts; parasites; veterinary medicine; weight loss; China;     Show all 14 Subjects
Abstract:
... BACKGROUND: Eimeria coccidiosis is a significant intestinal parasitic disease, which can lead to weight loss, disease and even death of many animals. At present, there is no information about the prevalence of Eimeria among the world’s endangered species of Père David’s deer (Elaphurus davidianus). Therefore, the purpose of this study is to identify an unknown Eimeria genus in the Père David’s dee ...
DOI:
10.1186/s12917-022-03308-2

13. Contribution to the knowledge on black flies (Diptera: Simuliidae) as vectors of Leucocytozoon (Haemosporida) parasites in Lithuania

Author:
Rita Žiegytė; Rasa Bernotienė
Source:
Parasitology international 2022 v.87 pp. 102515
ISSN:
1383-5769
Subject:
sporozoites,   etc   ; DNA; Leucocytozoon; Nematoda; Protozoa; Simulium; distress; evolution; microscopy; parasites; parasitology; polymerase chain reaction; poultry; salivary glands; Eastern European region; Lithuania;     Show all 16 Subjects
Abstract:
... Black flies (Diptera: Simuliidae) are among the most bothersome blood-sucking dipterans causing severe irritation and distress to poultry, wild birds, animals, and humans globally. These insects are vectors of viruses, bacteria, parasitic protozoans, and nematodes of humans and animals. Parasitic protozoa belonging to Haemosporida (Apicomplexa) are distributed worldwide and black flies are the pri ...
DOI:
10.1016/j.parint.2021.102515

14. Plasmodium early transcribed membrane proteins appear tailored to the host range of malaria parasites

Author:
Arianne M. Brandsma; Cecilie Hilmer; Manuel Rauch; Kai Matuschewski; Georgina N. Montagna
Source:
International journal for parasitology 2022 v.52 no.2-3 pp. 135-143
ISSN:
0020-7519
Subject:
sporozoites,   etc   ; Plasmodium berghei; Plasmodium falciparum; amino acid sequences; genetically modified organisms; host range; humans; liver; malaria; membrane proteins; mice; parasites; parasitology; vacuoles;     Show all 14 Subjects
Abstract:
... Early transcribed membrane proteins form a unique protein family in malaria parasites. These molecules are expressed during Plasmodium intracellular phases and inserted at the parasite parasitophorus vacuole membrane, which constitutes the host–parasite interface. Upregulated in infectious sporozoites 4 (UIS4) is an essential early transcribed membrane protein of liver stages of the murine malaria ...
DOI:
10.1016/j.ijpara.2021.08.005

15. Cloning and expression of a cDNA coding for Eimeria acervulina 25 kDa protein associated with oocyst and sporocyst walls

Author:
Mark C. Jenkins; Matthew Tucker; Carolyn Parker; Celia O’Brien; Katarzyna Miska
Source:
Veterinary parasitology 2022 v.309 pp. 109762
ISSN:
0304-4017
Subject:
sporozoites,   etc   ; Eimeria acervulina; Escherichia coli; fluorescent antibody technique; genes; humoral immunity; immunoblotting; oocysts; reverse transcriptase polymerase chain reaction; sporulation; veterinary parasitology;     Show all 11 Subjects
Abstract:
... The purpose of this study was to characterize a gene named EAH 00033530 identified by RNAseq analysis of sporulating Eimeria acervulina oocysts and its encoded protein. Quantitative RT-PCR analysis revealed peak expression of EAH 00033530 mRNA early (3–6 h) in sporulation followed by downregulation at 12–24 h. The gene for EAH 00033530 was expressed in Escherichia coli as a 70 kDa polyHis fusion p ...
DOI:
10.1016/j.vetpar.2022.109762
CHORUS:
10.1016/j.vetpar.2022.109762

16. Aggregata sinensis n. sp. (Apicomplexa: Aggregatidae), a new coccidian parasite from Amphioctopus fangsiao and Octopus minor (Mollusca: Octopodidae) in the Western Pacific Ocean

Author:
Jing Ren; Xiaodong Zheng
Source:
Parasitology research 2022 v.121 no.1 pp. 373-381
ISSN:
0932-0113
Subject:
sporozoites,   etc   ; Miozoa; Octopodidae; definitive hosts; genes; light microscopes; new species; nucleotide sequences; oocysts; parasites; parasitology; phylogeny; research; ribosomal RNA; China; Pacific Ocean;     Show all 16 Subjects
Abstract:
... A new species of parasitic Aggregata, Aggregata sinensis n. sp., is described from the octopuses Amphioctopus fangsiao (d'Orbigny, 1839–1841) and Octopus minor (Sasaki, 1920) (Mollusca: Octopodidae) in China based on morphological data and 18S ribosomal RNA (rRNA) gene sequences. The sexual gamogonic and sporogonic stages of the parasite were observed under light microscope. The sizes of oocysts w ...
DOI:
10.1007/s00436-021-07389-0

17. Direct injection of Amblyomma americanum ticks with Cytauxzoon felis

Author:
Tzushan S. Yang; Mason V. Reichard; Henry S. Marr; Leah A. Cohn; Laura Nafe; Nathan Whitehurst; Adam J. Birkenheuer
Source:
Ticks and tick-borne diseases 2022 v.13 no.1 pp. 101847
ISSN:
1877-959X
Subject:
sporozoites,   etc   ; Amblyomma americanum; Cytauxzoon felis; RNA; cats; digestive tract; erythrocytes; gametocytes; hemocoel; hemoparasites; hybridization; inoculum; repletion; reverse transcriptase polymerase chain reaction; ticks;     Show all 15 Subjects
Abstract:
... Cytauxzoon felis is a tick-borne hemoprotozoan parasite that causes life-threatening disease in domestic cats in the United States. Currently, the platforms for C. felis research are limited to natural or experimental infection of domestic cats. This study aims to develop an alternative model by infecting Amblyomma americanum ticks with C. felis via direct injection. Amblyomma americanum adults we ...
DOI:
10.1016/j.ttbdis.2021.101847

18. Spatial Distribution of PCR-Identified Species of Anopheles gambiae senu lato (Diptera: Culicidae) Across Three Eco-Vegetational Zones in Cross River State, Nigeria

Author:
H. S. Thabet; R. A. TagEldin; N. T. Fahmy; J. W. Diclaro; A. A. Alaribe; E. Ezedinachi; N. S. Nwachuku; F. O. Odey; H. Arimoto
Source:
Journal of medical entomology 2022 v.59 no.2 pp. 576-584
ISSN:
0022-2585
Subject:
sporozoites,   etc   ; Anopheles gambiae; Plasmodium falciparum; malaria; medical entomology; pyrethrins; regression analysis; restriction fragment length polymorphism; species identification; swamps; tropical rain forests; Nigeria;     Show all 12 Subjects
Abstract:
... Anopheles gambiae sensu lato complex (An. gambiae s.l.) describes a group of nine morphologically indistinguishable members that vary in their distribution, ability to transmit malaria, and susceptibility to pyrethroids. Here, we recorded the spatial patterns of PCR-identified An. gambiae s.l. complex species collected from four sites in Cross River State, Nigeria that represented three different ...
DOI:
10.1093/jme/tjab221

19. In vitro activity of selected natural products against Eimeria tenella sporozoites using reproduction inhibition assay

Author:
Ahmed Thabet; Ibrahim Alzuheir; Alaa Aldin Alnassan; Arwid Daugschies; Berit Bangoura
Source:
Parasitology research 2022 v.121 no.1 pp. 335-344
ISSN:
0932-0113
Subject:
sporozoites,   etc   ; Eimeria tenella; cinnamon oil; coccidiosis; coccidiostats; diarrhea; dose response; etiological agents; gene expression; ionophores; mortality; nutmeg; oils; parasites; parasitology; poultry; reproduction; research; weight loss;     Show all 19 Subjects
Abstract:
... Eimeria tenella is the causative agent of cecal coccidiosis in poultry characterized by weight loss, hemorrhagic diarrhea, and high mortality rates. Research into herbal candidates with possible anticoccidial activity has increased lately. As an alternative to animal experiments, an in vitro reproduction inhibition assay (RIA) was previously designed to determine the sensitivity of E. tenella isol ...
DOI:
10.1007/s00436-021-07360-z

20. Immunoproteomic analysis of the sporozoite antigens of Eimeria necatrix

Author:
Guanggang Qu; Zhiyang Xu; Wenbin Tuo; Charles Li; Hyun Lillehoj; Gen Wan; Haiwei Gong; Jinxin Huang; Guichuan Tian; Shanxin Li; Yuxin Liu; Liheng Liu
Source:
Veterinary parasitology 2022 v.301 pp. 109642
ISSN:
0304-4017
Subject:
sporozoites,   etc   ; Eimeria necatrix; Protozoa; blood serum; chickens; coccidiosis; computer software; growth performance; immune evasion; immunogenicity; intestines; mortality; parasites; silver; two-dimensional gel electrophoresis; vaccines; veterinary parasitology;     Show all 17 Subjects
Abstract:
... Eimeria necatrix, an apicomplexan protozoa of the genus Eimeria, causes intestinal coccidiosis that can reduce growth performance of poultry and result in high mortality in older chickens. In this report, the whole sporozoite proteins of E.necatrix were studied by two-dimensional electrophoresis (2-DE) and Western blotting using hyper-immune chicken serum containing E.necatrix-specific antibodies. ...
DOI:
10.1016/j.vetpar.2021.109642