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1. Addressing Reproducibility in Stem Cell and PRP Therapies

Author:
Anitua, Eduardo; Prado, Roberto
Source:
Trends in biotechnology 2019 v.37 no.4 pp. 340-344
ISSN:
0167-7799
Subject:
stem cells,   etc   ; protocols; therapeutics;     Show all 3 Subjects
Abstract:
... Stem cell and platelet-rich plasma (PRP) therapies are promising breakthroughs in the treatment of multiple conditions. However, the lack of reproducibility due to inaccurate reporting of the protocols used to obtain these biologics can hinder their therapeutic progress. A reporting guideline for biological therapies is required to address this issue. ...
DOI:
10.1016/j.tibtech.2018.11.010

2. Correction: Gold nanoparticle coatings as efficient adenovirus carriers to non-infectable stem cells

Author:
Hernandez, Yulan; Gonzalez-Pastor, Rebeca; Belmar-Lopez, Carolina; Mendoza, Gracia; de la Fuente, Jesus M.; Martin-Duque, Pilar
Source:
RSC advances 2019 v.9 no.9 pp. 4833
ISSN:
2046-2069
Subject:
stem cells,   etc   ; Adenoviridae; coatings; nanogold;     Show all 4 Subjects
Abstract:
... Correction for ‘Gold nanoparticle coatings as efficient adenovirus carriers to non-infectable stem cells’ by Yulan Hernandez et al., RSC Adv., 2019, 9, 1327–1334. ...
DOI:
10.1039/c9ra90008j

3. Cancer stem cells: A brief review of the current status

Author:
Kuşoğlu, Alican; Biray Avcı, Çığır
Source:
Gene 2019 v.681 pp. 80-85
ISSN:
0378-1119
Subject:
stem cells,   etc   ; data collection; neoplasms;     Show all 3 Subjects
Abstract:
... Cancer stem cells (CSCs) comprise the subpopulation of tumor bulk and acquire resistant to conventional therapies and are considered as the primary tumor initiator cells. Nowadays, the tumor heterogeneity originated from CSCs, and its progenitors are accepted as a mortifying drawback in front of the cancer therapies. However, escalating knowledge gained from studies investigating the biology of CS ...
DOI:
10.1016/j.gene.2018.09.052

4. Correction to: Efficient Differentiation of Human Embryonic Stem Cells Toward Dopaminergic Neurons Using Recombinant LMX1A Factor

Author:
Fathi, Ali; Rasouli, Hassan; Yeganeh, Meghdad; Salekdeh, Ghassem Hosseini; Baharvand, Hossein
Source:
Molecular biotechnology 2019 v.61 no.1 pp. 72
ISSN:
1073-6085
Subject:
embryonic stem cells,   etc   ; humans; neurons;     Show all 3 Subjects
Abstract:
... The original version of this article was published without article note. The article note is given below. ...
DOI:
10.1007/s12033-018-0131-2

5. Full of potential: Pluripotent stem cells for the systems biology of embryonic patterning

Author:
Heemskerk, Idse
Source:
Developmental biology 2019
ISSN:
0012-1606
Subject:
embryonic stem cells,   etc   ; gastrulation; mammals; models;     Show all 4 Subjects
Abstract:
... Recently, it has become possible to recapitulate embryonic patterning in vitro using embryonic stem cells. The technical advantages and reduced complexity of these embryoids make them ideally suited to rigorously test long standing paradigms for pattern formation in the mammalian embryo. Here, we discuss insights into the underlying mechanisms that have been gained from stem cell models to date, f ...
DOI:
10.1016/j.ydbio.2019.05.004

6. Simplifying the deployment of OGC web processing services (WPS) for environmental modelling – Introducing Tethys WPS Server

Author:
Qiao, Xiaohui; Li, Zhiyu; Ames, Daniel P.; Nelson, E. James; Swain, Nathan R.
Source:
Environmental modelling & software 2019 v.115 pp. 38-50
ISSN:
1364-8152
Subject:
stems,   etc   ; Internet; environmental models; user interface;     Show all 4 Subjects
Abstract:
... Developing a complex environmental modelling web application or “web app” can be a challenging task that requires integration of various models and data sources with ever-changing Internet technologies. Service-Oriented Architecture (SOA) has been shown to be useful for building complex modelling workflows. However, compared with other types of web services, such as those for data delivery and map ...
DOI:
10.1016/j.envsoft.2019.01.021

7. Correction to: Plant stem cells: what we know and what is anticipated

Author:
Warghat, Ashish R.; Thakur, Kanika; Sood, Archit
Source:
Molecular biology reports 2019 v.46 no.2 pp. 2595-2596
ISSN:
0301-4851
Subject:
stem cells,   etc   ; molecular biology; plants (botany);     Show all 3 Subjects
Abstract:
... This correction stands to correct Fig. 2 of the original article as Fig. 2 provided in the manuscript has been modified. The corrected figure has been provided herewith. The original article has been corrected. ...
DOI:
10.1007/s11033-018-4393-3

8. Wnt signaling and bone regeneration: Can't have one without the other

Author:
Leucht, Philipp; Lee, Sooyeon; Yim, Nury
Source:
Biomaterials 2019 v.196 pp. 46-50
ISSN:
0142-9612
Subject:
stem cells,   etc   ; homeostasis; signal transduction; tissue repair;     Show all 4 Subjects
Abstract:
... Advances in the understanding of the complexities of the Wnt signaling pathway during development and tissue homeostasis have made the Wnt pathway one of the prime candidates for translational applications during tissue regeneration. Wnts are key components of the stem cell niche and are short range signaling molecules responsible for cellular decisions such as proliferation and differentiation. S ...
DOI:
10.1016/j.biomaterials.2018.03.029

9. To regenerate or not to regenerate: factors that drive plant regeneration

Author:
Sugimoto, Kaoru; Temman, Haruka; Kadokura, Satoshi; Matsunaga, Sachihiro
Source:
Current opinion in plant biology 2019 v.47 pp. 138-150
ISSN:
1369-5266
Subject:
stem cells,   etc   ; epigenetics; meristems; transcription (genetics);     Show all 4 Subjects
Abstract:
... Plants have a remarkable regenerative capacity, but it varies widely among species and tissue types. Whether plant cells/tissues initiate regeneration largely depends on the extent to which they are constrained to their original tissue fate. Once cells start the regeneration program, they acquire a new fate, form meristems, and develop into organs. During these processes, the cells must continuous ...
DOI:
10.1016/j.pbi.2018.12.002

10. 4-dehydroxyepisarcovagine A, a new steroidal alkaloid from Sarcococca pruniformis Lindl.

Author:
Wu, J.-C.; Huo, S.-J.; Du, J.
Source:
Natural product research 2019 v.33 no.2 pp. 169-173
ISSN:
1478-6427
Subject:
stems,   etc   ; Sarcococca; alkaloids; roots; spectral analysis;     Show all 5 Subjects
Abstract:
... A new steroidal alkaloid, 4-dehydroxyepisarcovagine A (1), along with seven known alkaloids, sarcovagine D (2), sarcovagenine C (3), epoxysarcovagenine D (4), Pachysamine L (5), Pachysamine E (6), sarcovagine A (7) and sarcovagine B (8), was isolated from the roots and stems of Sarcococca pruniformis Lindl. The structure of compound 1 was elucidated by means of spectroscopic analysis. ...
DOI:
10.1080/14786419.2018.1440226

11. Enhanced single-cell viability using 30Kc6 for efficient expansion of human induced pluripotent stem cells

Author:
Ryu, Jina; Park, Sang Wook; Park, Hee Ho; Park, Tai Hyun
Source:
Process biochemistry 2019 v.78 pp. 161-168
ISSN:
1359-5113
Subject:
embryonic stem cells; induced pluripotent stem cells,   etc   ; apoptosis; culture dishes; epithelium; genes; humans; mitochondria; viability;     Show all 9 Subjects
Abstract:
... Human pluripotent stem cells (hPSCs), such as human induced pluripotent stem cells (hiPSCs) and human embryonic stem cells (hESCs), have been widely used in stem cell research. hPSCs form colonies in culture dishes and are passaged as clumps. If the cells are dissociated into single cells, epithelial structures are disrupted, and rapid apoptosis is induced. The low viability of single cells restri ...
DOI:
10.1016/j.procbio.2019.01.017

12. Estimating net biomass production and loss from repeated measurements of trees in forests and woodlands: Formulae, biases and recommendations

Author:
Kohyama, Takashi S.; Kohyama, Tetsuo I.; Sheil, Douglas
Source:
Forest ecology and management 2019 v.433 pp. 729-740
ISSN:
0378-1127
Subject:
stem elongation; stems,   etc   ; biomass production; carbon; mortality; rain forests; tree growth; trees; woodlands; Indonesia; Japan;     Show all 11 Subjects
Abstract:
... There is widespread interest in ensuring that assessment and knowledge of changes in forest biomass, and associated carbon gains or losses, are accurate and unbiased. Repeated measurements of individually-marked trees in permanent plots permit the estimation of rates of biomass production by tree growth and recruitment and of loss from mortality. But there are challenges, for example, simple estim ...
DOI:
10.1016/j.foreco.2018.11.010

13. Pluripotent stem cell-derived cochlear cells: a challenge in constant progress

Author:
Czajkowski, Amandine; Mounier, Anaïs; Delacroix, Laurence; Malgrange, Brigitte
Source:
Cellular and molecular life sciences 2019 v.76 no.4 pp. 627-635
ISSN:
1420-682X
Subject:
embryonic stem cells; induced pluripotent stem cells,   etc   ; deafness; humans; mice; therapeutics;     Show all 6 Subjects
Abstract:
... Hearing loss is a common affection mainly resulting from irreversible loss of the sensory hair cells of the cochlea; therefore, developing therapies to replace missing hair cells is essential. Understanding the mechanisms that drive their formation will not only help to unravel the molecular basis of deafness, but also give a roadmap for recapitulating hair cells development from cultured pluripot ...
DOI:
10.1007/s00018-018-2950-5

14. Correction to: ZIKV infection effects changes in gene splicing, isoform composition and lncRNA expression in human neural progenitor cells

Author:
Hu, Benxia; Huo, Yongxia; Yang, Liping; Chen, Guijun; Luo, Minhua; Yang, Jinlong; Zhou, Jumin
Source:
Virology journal 2019 v.16 no.1 pp. 17
ISSN:
1743-422X
Subject:
neural stem cells,   etc   ; National Science Foundation; genes; grants; humans; China;     Show all 6 Subjects
Abstract:
... In the original publication of this article [1], two grants from National Science Foundation of China and Yunnan Provincial Government (U1602226) and by National Science Foundation of China (2016YFC1200404) were omitted in the ‘Funding’ section. The correct ‘Funding’ section is below. ...
DOI:
10.1186/s12985-019-1122-z

15. How to organize bidirectional tissue production?

Author:
Chiang, Min-Hao; Greb, Thomas
Source:
Current opinion in plant biology 2019 v.51 pp. 15-21
ISSN:
1369-5266
Subject:
stem cells,   etc   ; biomass production; cambium; vascular tissues; wood;     Show all 5 Subjects
Abstract:
... The cambium is a plant-borne stem cell system producing wood and bast, two distinct types of vascular tissues, in strictly opposite directions. Thereby, the cambium contributes substantially to terrestrial biomass accumulation and represents the basis for the formation of large plant bodies. Although the bidirectional mode of tissue production by a common stem cell pool holds interesting implicati ...
DOI:
10.1016/j.pbi.2019.03.003

16. A novel hydraulic biogas digester controlling the scum formation in batch and semi-continuous tests using banana stems

Author:
Pan, Shiyou; Wen, Chuan; Liu, Qiangqiang; Chi, Yue; Mi, Huizhi; Li, Zhenchong; Du, Liqin; Huang, Ribo; Wei, Yutuo
Source:
Bioresource technology 2019 v.286 pp. 121372
ISSN:
0960-8524
Subject:
stems,   etc   ; bananas; biogas; feedstocks; fermentation; gas production (biological); straw;     Show all 7 Subjects
Abstract:
... Scum formation is a widespread phenomenon and causes serious damage in straw biogas digesters. A 10-L novel hydraulic conical digester for controlling scum was developed in this work and compared with a hydraulic cylindrical digester that simulated the conventional digester. After 30 d of batch and 120 d of semi-continuous fermentations using banana stems, the scum volumes of in cylindrical digest ...
DOI:
10.1016/j.biortech.2019.121372

17. Computational Strategies for Niche-Dependent Cell Conversion to Assist Stem Cell Therapy

Author:
del Sol, Antonio; Okawa, Satoshi; Ravichandran, Srikanth
Source:
Trends in biotechnology 2019 v.37 no.7 pp. 687-696
ISSN:
0167-7799
Subject:
stem cells,   etc   ; cell transplantation; medicine; phenotype; protocols; tissue repair;     Show all 6 Subjects
Abstract:
... The field of regenerative medicine has blossomed in recent decades. However, the ultimate goal of tissue regeneration – replacing damaged or aged cells with healthy functioning cells – still faces a number of challenges. In particular, better understanding of the role of the cellular niche in shaping stem cell phenotype and conversion would aid in improving current protocols for stem cell therapie ...
DOI:
10.1016/j.tibtech.2019.01.005

18. Dgcr8 knockout approaches to understand microRNA functions in vitro and in vivo

Author:
Guo, Wen-Ting; Wang, Yangming
Source:
Cellular and molecular life sciences 2019 v.76 no.9 pp. 1697-1711
ISSN:
1420-682X
Subject:
embryonic stem cells,   etc   ; biogenesis; microRNA; models; phenotype; tissues;     Show all 6 Subjects
Abstract:
... Biologic function of the majority of microRNAs (miRNAs) is still unknown. Uncovering the function of miRNAs is hurdled by redundancy among different miRNAs. The deletion of Dgcr8 leads to the deficiency in producing all canonical miRNAs, therefore, overcoming the redundancy issue. Dgcr8 knockout strategy has been instrumental in understanding the function of miRNAs in a variety of cells in vitro a ...
DOI:
10.1007/s00018-019-03020-9

19. Differences of Cd uptake and expression of MT family genes and NRAMP2 in two varieties of ryegrasses

Author:
Li, Yanhua; Qin, Yuli; Xu, Weihong; Chai, Yourong; Li, Tao; Zhang, Chunlai; Yang, Mei; He, Zhangmi; Feng, Deyu
Source:
Environmental science and pollution research international 2019 v.26 no.14 pp. 13738-13745
ISSN:
0944-1344
Subject:
stems,   etc   ; Lolium; absorption; cadmium; genes; hyperaccumulators; leaves; roots; soil;     Show all 9 Subjects
Abstract:
... In order to understand the mechanism of the difference of Cd absorption and Cd enrichment in different ryegrass varieties, pot experiment was conducted to study on the response of two varieties of ryegrass (Bond and Abbott) to Cd stress as well as the differences of Cd uptake and expression of MT family genes and NRAMP2. Results showed that root dry weights of two varieties and shoot dry weights o ...
DOI:
10.1007/s11356-018-2649-z

20. Hear Pancreatic Cancer Stem Cells ROR

Author:
Yao, Wantong; Maitra, Anirban
Source:
Cell 2019 v.177 no.3 pp. 516-518
ISSN:
0092-8674
Subject:
stem cells,   etc   ; aggression; genomics; pancreatic neoplasms; retinoic acid; transcription factors;     Show all 6 Subjects
Abstract:
... In this issue of Cell, Lytle et al. (2019) integrate functional genomic approaches to identify molecular dependencies of pancreatic cancer stem cells that may be exploited therapeutically. The comprehensive analysis reveals an unexpected role for retinoic acid receptor-related orphan receptor gamma (RORγ), a T-cell-associated transcription factor, in defining the stemness and the aggressive behavi ...
DOI:
10.1016/j.cell.2019.04.002