PubAg

Main content area

You searched for: Subject "superoxide dismutase" Remove constraint Subject: "superoxide dismutase"
Start Over

Search

16,755  Search Results

« Previous | 1 - 20 of 16,755 |
Number of results to display per page

Search Results

1. A new phenanthrene dimer from Dendrobium palpebrae

Author:
Kyokong, Napat; Muangnoi, Chawanphat; Thaweesest, Wuttinont; Kongkatitham, Virunh; Likhitwitayawuid, Kittisak; Rojsitthisak, Pornchai; Sritularak, Boonchoo
Source:
Journal of Asian natural products research 2019 v.21 no.4 pp. 391-397
ISSN:
1477-2213
Subject:
superoxide dismutase,   etc   ; Dendrobium; antioxidant activity; dose response; hydroxyl radicals; phenanthrenes;     Show all 6 Subjects
Abstract:
... A new phenanthrene dimer, namely dendropalpebrone (1), was isolated from the whole plant of Dendrobium palpebre, along with nine known compounds (2–10). All of the isolates were evaluated for their hydroxyl radical scavenging effects using a deoxyribose assay. Dendroflorin (10) showed an appreciable activity, and therefore was selected for further studied in RAW264.7 cells. Compound 10 significant ...
DOI:
10.1080/10286020.2018.1429416

2. Stability and Local Unfolding of SOD1 in the Presence of Protein Crowders

Author:
Bille, Anna; Jensen, Kristine Steen; Mohanty, Sandipan; Akke, Mikael; Irbäck, Anders
Source:
TheJournal of physical chemistry 2019 v.123 no.9 pp. 1920-1930
ISSN:
1520-5207
Subject:
superoxide dismutase,   etc   ; cattle; nuclear magnetic resonance spectroscopy; proteins; trypsin inhibitors;     Show all 5 Subjects
Abstract:
... Using NMR and Monte Carlo (MC) methods, we investigate the stability and dynamics of superoxide dismutase 1 (SOD1) in homogeneous crowding environments, where either bovine pancreatic trypsin inhibitor (BPTI) or the B1 domain of streptococcal protein G (PGB1) serves as a crowding agent. By NMR, we show that both crowders, and especially BPTI, cause a drastic loss in the overall stability of SOD1 i ...
DOI:
10.1021/acs.jpcb.8b10774

3. Revelation of microalgae's lipid production and resistance mechanism to ultra-high Cd stress by integrated transcriptome and physiochemical analyses

Author:
Lu, JingJing; Ma, YanLing; Xing, GuanLan; Li, WenLi; Kong, XiangXue; Li, JinYu; Wang, LinJing; Yuan, HongLi; Yang, JinShui
Source:
Environmental pollution 2019 v.250 pp. 186-195
ISSN:
0269-7491
Subject:
superoxide dismutase,   etc   ; Auxenochlorella protothecoides; alkanes; antioxidants; biofuels; bioremediation; cadmium; calcium; habitats; ions; lipids; microalgae; peroxidase; transcriptome;     Show all 14 Subjects
Abstract:
... The ultra-high Cd polluted environment is a special habitat in nature. Analysis of the biological adaptation and resistance mechanism of Auxenochlorella protothecoides UTEX234 to ultra-high Cd stress would offer some inspiring understanding on Cd detoxification mechanism and help discovering highly active bioremediation agents. In this study, integrated analyses of the transcriptome, multi-physiol ...
DOI:
10.1016/j.envpol.2019.04.018

4. Toxic effect and bioaccumulation of selenium in green alga Chlorella pyrenoidosa

Author:
Zhao, Yufeng; Song, Xinshan; Cao, Xin; Wang, Yuhui; Si, Zhihao; Chen, Yan
Source:
Journal of applied phycology 2019 v.31 no.3 pp. 1733-1742
ISSN:
0921-8971
Subject:
superoxide dismutase,   etc   ; Chlorella pyrenoidosa; bioaccumulation; biomass; catalase; developmental stages; enzyme activity; metabolism; microalgae; selenites; selenium; toxicity;     Show all 12 Subjects
Abstract:
... Se is required for the growth and metabolism of many species of microalgae. However, high concentrations of Se show toxicity to microalgal cells. In the study, the biomass, growth rate, total Se content, organic Se content, SOD, CAT, and LPO of Chlorella pyrenoidosa in an environment containing Se were determined to explore the effects of selenite on the growth of C. pyrenoidosa in different growt ...
DOI:
10.1007/s10811-018-1711-z

5. Effects of hydraulic retention time and proteins on sludge toxicity for 4‐chlorophenol wastewater treatment in sequencing batch reactors

Author:
Zhao, Jianguo; Li, Yahe; Chen, Xiurong; Wang, Lu; Xu, Yan
Source:
Water and environment journal 2019 v.33 no.2 pp. 158-166
ISSN:
1747-6585
Subject:
superoxide dismutase,   etc   ; 4-chlorophenol; ABC transporters; activated sludge; heat stress; pollutants; risk; toxicity; uncertainty; wastewater treatment;     Show all 10 Subjects
Abstract:
... Due to the higher uncertainty of environmental risk for pollutants’ treatment by activated sludge, 10 mg/L influent 4‐chlorophenol (4‐CP) treated via a sequencing batch reactor (SBR) was used as acclimated SBR. Another SBR was used as control SBR without 4‐CP. The effects of hydraulic retention time (HRT) and proteins on sludge toxicity for 4‐CP treatment were analysed, and compared to the control ...
DOI:
10.1111/wej.12386

6. Protective effects of 3β-angeloyloxy-8β, 10β-dihydroxyeremophila-7(11)-en-12, 8α-lactone on paraquat-induced oxidative injury in SH-SY5Y cells

Author:
Wang, Qi-Lin; Guo, Chao; Qi, Jie; Ma, Jia-Hui; Liu, Fang-Yuan; Lin, Shi-Qi; Zhang, Cai-Yun; Xie, Wei-Dong; Zhuang, Jing-Jing; Li, Xia
Source:
Journal of Asian natural products research 2019 v.21 no.4 pp. 364-376
ISSN:
1477-2213
Subject:
superoxide dismutase,   etc   ; Parkinson disease; caspase-3; caspase-9; oxidative stress; paraquat; protective effect;     Show all 7 Subjects
Abstract:
... 3β-Angeloyloxy-8β,10β-dihydroxyeremophila-7(11)-en-12,8α-lactone (FJ1) inhibited effectively paraquat (PQ)-induced injury in SH-SY5Y cells. In this way, FJ1 was shown to reverse the PQ-induced activation of caspase-9 and caspase-3, the increase in Bax/Bcl-2 ratio, and the release of cytochrome c. The mechanism was associated with a reduction of oxidative stress, including the decrease in the level ...
DOI:
10.1080/10286020.2017.1423057

7. Taurine protects against NMDA-induced retinal damage by reducing retinal oxidative stress

Author:
Jafri, Azliana Jusnida Ahmad; Agarwal, Renu; Iezhitsa, Igor; Agarwal, Puneet; Ismail, Nafeeza Mohd
Source:
Amino acids 2019 v.51 no.4 pp. 641-646
ISSN:
0939-4451
Subject:
superoxide dismutase,   etc   ; apoptosis; catalase; ganglia; glutathione; malondialdehyde; oxidative stress; rats; retina; staining; taurine;     Show all 11 Subjects
Abstract:
... This study aimed to evaluate effect of TAU on NMDA-induced changes in retinal redox status, retinal cell apoptosis and retinal morphology in Sprague–Dawley rats. Taurine was injected intravitreally as pre-, co- or post-treatment with NMDA and 7 days post-treatment retinae were processed for estimation of oxidative stress, retinal morphology using H&E staining and retinal cell apoptosis using TUNEL ...
DOI:
10.1007/s00726-019-02696-4

8. Polysaccharides from Tetrastigma hemsleyanum Diels et Gilg: Extraction optimization, structural characterizations, antioxidant and antihyperlipidemic activities in hyperlipidemic mice

Author:
Ru, Yi; Chen, Xiao; Wang, Jian; Guo, Longhua; Lin, Zhenyu; Peng, Xin; Qiu, Bin
Source:
International journal of biological macromolecules 2019 v.125 pp. 1033-1041
ISSN:
0141-8130
Subject:
superoxide dismutase,   etc   ; Tetrastigma; antioxidants; blood lipids; glutathione peroxidase; hyperlipidemia; liver; mice; molecular weight; oxidative stress; polysaccharides;     Show all 11 Subjects
Abstract:
... In this study, a novel polysaccharide TDGP-3 from Tetrastigma hemsleyanum Diels et Gilg was extracted by enzymolysis-ultrasonic assisted extraction (EUAE) method and its antioxidant and hypolipidemic activities were evaluated. With a molecular weight of 3.31 × 105 Da, TDGP-3 was composed of 1,4-Glcp, 1,4-Glap and 1,3,6-Manp linkage in the main chain. TDGP-3 showed potential effects on relieving hy ...
DOI:
10.1016/j.ijbiomac.2018.11.236

9. Comparative behavior of two gram positive Cr6+ resistant bacterial strains Bacillus aerius S1 and Brevibacterium iodinum S2 under hexavalent chromium stress

Author:
Elahi, Amina; Rehman, Abdul
Source:
Biotechnology reports 2019 v.21 pp. e00307
ISSN:
2215-017X
Subject:
superoxide dismutase,   etc   ; Brevibacterium iodinum; antioxidants; biosorption; biotechnology; chromium; pH; tannery effluents;     Show all 8 Subjects
Abstract:
... Bacillus aerius S1 and Brevibacterium iodinum S2 showed maximum growth at 37 °C and pH 8. B. aerius and B. iodinum could resist Cr6+ upto 30 and 35 mM and biosorption proficiency (q) of B. aerius S1 was 19, 27, 52 and 34 mM/g while for B. iodinum S2, it was 39, 50, 23 and 16 mM/g mM/g after 2, 4, 6 and 8 days of incubation. A pronounced rise in antioxidant enzymes activities was determined in B. a ...
DOI:
10.1016/j.btre.2019.e00307

10. Subcellular cadmium distribution and antioxidant enzymatic activities in the leaves of four Hylotelephium spectabile populations exhibit differences in phytoextraction potential

Author:
Guo, Junmei; Yang, Jun; Yang, Junxing; Chen, Tongbin; Guo, Lin
Source:
International journal of phytoremediation 2019 v.21 no.3 pp. 209-216
ISSN:
1549-7879
Subject:
superoxide dismutase,   etc   ; Hylotelephium spectabile; antioxidants; bioaccumulation factor; cadmium; catalase; enzyme activity; growth retardation; leaves; peroxidase; phytoaccumulation;     Show all 11 Subjects
Abstract:
... Hylotelephium spectabile with high tolerance to cadmium (Cd) might be a potential candidate for phytoremediation. However, the mechanisms for Cd accumulation and tolerance in H. spectabile are poorly understood. Four H. spectabile populations, namely HB1, HB2, JS, and LN, were selected to investigate their Cd extraction potential and the underlying mechanism of Cd accumulation, focusing on subcell ...
DOI:
10.1080/15226514.2018.1524836

11. Superoxide dismutase 3 facilitates the chondrogenesis of bone marrow-derived mesenchymal stem cells

Author:
Shi, Yuanyuan; Hu, Xiaoqing; Zhang, Xin; Cheng, Jin; Duan, Xiaoning; Fu, Xin; Zhang, Jiying; Ao, Yingfang
Source:
Biochemical and biophysical research communications 2019 v.509 no.4 pp. 983-987
ISSN:
0006-291X
Subject:
superoxide dismutase,   etc   ; bone marrow; cartilage; chondrogenesis; collagen; mesenchymal stromal cells; protein content; superoxide anion; therapeutics;     Show all 9 Subjects
Abstract:
... Articular cartilage defects are considered a major clinical problem because they cannot heal by themselves. To date, bone marrow-derived mesenchymal stem cells (BMSCs)-based therapy has been widely applied for cartilage repair. However, fibrocartilage was often generated after BMSC therapy; therefore, there is an urgent need to stimulate and maintain BMSCs chondrogenic differentiation. The specifi ...
DOI:
10.1016/j.bbrc.2019.01.042

12. Stability Effect of Quinary Interactions Reversed by Single Point Mutations

Author:
Gnutt, David; Timr, Stepan; Ahlers, Jonas; König, Benedikt; Manderfeld, Emily; Heyden, Matthias; Sterpone, Fabio; Ebbinghaus, Simon
Source:
Journal of the American Chemical Society 2019 v.141 no.11 pp. 4660-4669
ISSN:
1520-5126
Subject:
superoxide dismutase,   etc   ; amino acids; mammals; mutants; mutational analysis; point mutation; protein folding; proteins; structural biology;     Show all 9 Subjects
Abstract:
... In cells, proteins are embedded in a crowded environment that controls their properties via manifold avenues including weak protein–macromolecule interactions. A molecular level understanding of these quinary interactions and their contribution to protein stability, function, and localization in the cell is central to modern structural biology. Using a mutational analysis to quantify the energetic ...
DOI:
10.1021/jacs.8b13025

13. Sestrin2 increases in aortas and plasma from aortic dissection patients and alleviates angiotensin II-induced smooth muscle cell apoptosis via the Nrf2 pathway

Author:
Xiao, Ting; Zhang, Le; Huang, Ying; Shi, Ying; Wang, Jing; Ji, Qingwei; Ye, Jing; Lin, Yingzhong; Liu, Hongtao
Source:
Life sciences 2019 v.218 pp. 132-138
ISSN:
0024-3205
Subject:
superoxide dismutase,   etc   ; T-lymphocytes; apoptosis; blood sampling; coculture; macrophages; malondialdehyde; oxidative stress; patients; proteins; smooth muscle;     Show all 11 Subjects
Abstract:
... Previous studies have demonstrated that oxidative stress is closely related to aortic dissection (AD). Sestrin2 (Sesn2) is an important antioxidant protein, and this study aimed to investigate whether Sesn2 participates in AD and the possible mechanisms.Sesn2 expression was detected in aortas collected from AD patients and normal donors. In addition, blood samples were collected from AD patients a ...
DOI:
10.1016/j.lfs.2018.12.043

14. Lucigenin-Tris(2-carboxyethyl)phosphine Chemiluminescence for Selective and Sensitive Detection of TCEP, Superoxide Dismutase, Mercury(II), and Dopamine

Author:
Saqib, Muhammad; Bashir, Shahida; Li, Haijuan; Wang, ShanShan; Jin, Yongdong
Source:
Analytical chemistry 2019 v.91 no.4 pp. 3070-3077
ISSN:
1520-6882
Subject:
superoxide dismutase,   etc   ; blood serum; catalysts; chemical species; chemiluminescence; dopamine; hydrogen peroxide; ions; lakes; mercury; phosphine;     Show all 11 Subjects
Abstract:
... Development of simple and effective chemiluminescence (CL) systems for multiple sensing applications is significantly important but still a challenge. Until now, the majority of CL systems primarily utilized hydrogen peroxide (H₂O₂) as coreactant, which is limited in its stability and selectivity due to the easy decomposition of H₂O₂ in the presence of several ions. In this study, we develop a new ...
DOI:
10.1021/acs.analchem.8b05486

15. Oxidant related biochemical traits are significant indices in triticale grain yield under drought stress condition

Author:
Riasat, Mehrnaz; Kiani, Sholeh; Saed-Mouchehsi, Armin; Pessarakli, Mohamad
Source:
Journal of plant nutrition 2019 v.42 no.2 pp. 111-126
ISSN:
1532-4087
Subject:
superoxide dismutase,   etc   ; cultivars; genotype; grain yield; hydrogen peroxide; irrigation; malondialdehyde; oxidants; rain; screening; triticale; water stress;     Show all 12 Subjects
Abstract:
... Two separate experiments, one as drought stress conditions and the other one as the normal irrigation conditions based on randomized complete block design with three replications were implemented to examine 20 triticale (Triticoseclae wittamack X) genotypes of which 19 genotypes have recently been generated by crossing different parent lines and the other one was Javaniloo, a common cultivar. Base ...
DOI:
10.1080/01904167.2018.1549675

16. Charge-Selective Delivery of Proteins Using Mesoporous Silica Nanoparticles Fused with Lipid Bilayers

Author:
Shi, Hongdong; Liu, Shuzhang; Cheng, Junjie; Yuan, Siming; Yang, Yang; Fang, Tiantian; Cao, Kaiming; Wei, Kaiju; Zhang, Qianling; Liu, Yangzhong
Source:
ACS applied materials & interfaces 2019 v.11 no.4 pp. 3645-3653
ISSN:
1944-8252
Subject:
superoxide dismutase,   etc   ; blood serum; encapsulation; fluorescence; fluorescent proteins; lipid bilayers; lipids; nanoparticles; porous media; silica; therapeutics;     Show all 11 Subjects
Abstract:
... Efficient and safe intracellular delivery of proteins is highly desired in the development of protein therapeutics. Current methods of protein delivery commonly suffer from low loading efficiency, low stability in serum, and lack of versatility for different proteins. Here, we developed a platform for efficient protein delivery using mesoporous silica nanoparticles (MSN) with lipid fusion. By diff ...
DOI:
10.1021/acsami.8b15390

17. Characterization of residue-specific glutathionylation of CSF proteins in multiple sclerosis – A MS-based approach

Author:
Srivastava, Deepsikha; Kukkuta Sarma, Gosala Raja; Dsouza, Delon Snehal; Muralidharan, Monita; Srinivasan, Krishnamachari; Mandal, Amit Kumar
Source:
Analytical biochemistry 2019 v.564-565 pp. 108-115
ISSN:
0003-2697
Subject:
superoxide dismutase,   etc   ; cysteine; hypertension; interleukin-18; oxidative stress; patients; proteins; proteomics; relapse; sclerosis;     Show all 10 Subjects
Abstract:
... Reduction of a disulfide linkage between cysteine residues in proteins, a standard step in the preanalytical preparation of samples in conventional proteomics approach, presents a challenge to characterize S-glutathionylation of proteins. S-glutathionylation of proteins has been reported in medical conditions associated with high oxidative stress. In the present study, we attempted to characterize ...
DOI:
10.1016/j.ab.2018.10.015

18. Chronic infusion of berberine into the hypothalamic paraventricular nucleus attenuates hypertension and sympathoexcitation via the ROS/Erk1/2/iNOS pathway

Author:
Tian, Hua; Kang, Yu-Ming; Gao, Hong-Li; Shi, Xiao-Lian; Fu, Li-Yan; Li, Ying; Jia, Xiu-Yue; Liu, Kai-Li; Qi, Jie; Li, Hong-Bao; Chen, Yan-Mei; Chen, Wen-Sheng; Cui, Wei; Zhu, Guo-Qing; Yu, Xiao-Jing
Source:
Phytomedicine 2019 v.52 pp. 216-224
ISSN:
0944-7113
Subject:
superoxide dismutase,   etc   ; animal disease models; berberine; cerebrospinal fluid; hypertension; inducible nitric oxide synthase; norepinephrine; rats;     Show all 8 Subjects
Abstract:
... Berberine (BBR), a Chinese traditional herbal medicine, has many pharmacologic benefits such as anti-inflammation and anti-oxidation. It is widely used in clinical treatment of cardiovascular diseases such as hypertension. However, the mechanism of how BBR attenuates hypertension through affecting central neural system is not clear.This study was designed to determine whether chronic infusion of B ...
DOI:
10.1016/j.phymed.2018.09.206

19. A combined experimental-computational investigation on water adsorption in various ZIFs with the SOD and RHO topologies

Author:
Gao, Meizhen; Wang, Jing; Rong, Zhenghao; Shi, Qi; Dong, Jinxiang
Source:
RSC advances 2018 v.8 no.69 pp. 39627-39634
ISSN:
2046-2069
Subject:
superoxide dismutase,   etc   ; adsorption; porosity; topology; van der Waals forces; zinc;     Show all 6 Subjects
Abstract:
... We synthesized a series of seven zeolitic imidazolate frameworks (ZIFs), namely ZIF-8, ZIF-90, SIM-1, MAF-6, ZIF-25, ZIF-93 and ZIF-97. Then we investigated the adsorption behavior of water for each ZIF via a combined experimental-computational method. We focused on the van der Waals (vdW) and electrostatic contributions to their water adsorption capacity. The results showed that the vdW interacti ...
DOI:
10.1039/c8ra08460b

20. To Claim Growth Turf, mTOR Says SOD Off

Author:
Kong, Hyewon; Chandel, Navdeep S.
Source:
Molecular cell 2018 v.70 no.3 pp. 383-384
ISSN:
1097-2765
Subject:
superoxide dismutase,   etc   ; homeostasis; lawns and turf; neoplasm cells; neoplasms;     Show all 5 Subjects
Abstract:
... Maintaining redox balance in cancer cells is essential for tumor development and progression. In this issue of Molecular Cell, Tsang et al. (2018) identify an evolutionarily conserved mTORC1-dependent mechanism by which cancer cells control redox homeostasis in ischemic tumor microenvironment. ...
DOI:
10.1016/j.molcel.2018.04.015