PubAg

Main content area

You searched for: Subject "toxicity" Remove constraint Subject: "toxicity"
Start Over

Search

44,648  Search Results

« Previous | 1 - 20 of 44,648 |
Number of results to display per page

Search Results

1. Correction to: Effect of biosolid hydrochar on toxicity to earthworms and brine shrimp

Author:
Melo, TatianeMedeiros; Bottlinger, Michael; Schulz, Elke; Leandro, WilsonMozena; de Aguiar Filho, AdelmoMenezes; Ok, YongSik; Rinklebe, Jörg
Source:
Environmental geochemistry and health 2018 v.40 no.1 pp. 2-558
ISSN:
0269-4042
Subject:
toxicity,   etc   ; Artemia; earthworms; hydrochars;     Show all 4 Subjects
Abstract:
... Unfortunately, in the original publication of the article, Prof. Yong Sik Ok’s affiliation was incorrectly published. The author’s affiliation is as follows. ...
DOI:
10.1007/s10653-017-0042-3

2. Cigarette butts may have low toxicity to soil-dwelling invertebrates: Evidence from a land snail

Author:
Gill, Hussan; Rogers, Kyler; Rehman, Bilal; Moynihan, John; Bergey, Elizabeth A.
Source:
The Science of the total environment 2018 v.628-629 pp. 6-561
ISSN:
0048-9697
Subject:
toxicity; toxicity testing,   etc   ; cigarettes; habitats; mortality; snails; soil; toxins; woodlands;     Show all 9 Subjects
Abstract:
... Cigarette butts are a common form of litter that is often deposited on soil, where toxins from butts may affect soil-dwelling organisms. We examined possible toxicity of cigarette butts to the woodland snail Anguispira alternata using a toxicity study with cigarette butt effluent and a lab-based habitat choice experiment in which snails could feed or rest on areas with different butt densities. No ...
DOI:
10.1016/j.scitotenv.2018.02.080

3. Differential uptake of and sensitivity to diphenhydramine in embryonic and larval zebrafish

Author:
Kristofco, Lauren A.; Haddad, Samuel P.; Chambliss, C. Kevin; Brooks, Bryan W.
Source:
Environmental toxicology and chemistry 2018 v.37 no.4 pp. 7-1181
ISSN:
0730-7268
Subject:
toxicity; toxicity testing,   etc   ; Danio rerio; chorion; fish; larvae;     Show all 6 Subjects
Abstract:
... The zebrafish fish embryo toxicity (FET) test is increasingly employed for alternative toxicity studies, yet our previous research identified increased sensitivity of zebrafish slightly older than embryos employed in FET methods (0–4 d postfertilization [dpf]). We identified rapid steady‐state accumulation of diphenhydramine across zebrafish embryo and larval stages. However, significantly (p < 0. ...
DOI:
10.1002/etc.4068

4. Analytical methodologies for arsenic speciation in macroalgae: A critical review

Author:
Reis, Vanessa A.T.; Duarte, Armando C.
Source:
Trends in analytical chemistry 2018 v.102 pp. 15-184
ISSN:
0165-9936
Subject:
toxicity,   etc   ; arsenic; estuaries; macroalgae; nutrients;     Show all 5 Subjects
Abstract:
... Marine and estuarine macroalgae are increasingly used for direct consumption, due to its high content of essential nutrients. However, the toxicity of chemical forms of arsenic (As) present in macroalgae are becoming of great concern and an important research topic.This review will discuss the sophisticated analytical methodologies used for arsenic speciation, as well the investigation of cheaper ...
DOI:
10.1016/j.trac.2018.02.003

5. Toxicity of Doxorubicin (Dox) to different experimental organ systems

Author:
Pugazhendhi, Arivalagan; Edison, Thomas Nesakumar Jebakumar Immanuel; Velmurugan, Bharath Kumar; Jacob, Joe Antony; Karuppusamy, Indira
Source:
Life sciences 2018 v.200 pp. 5-30
ISSN:
0024-3205
Subject:
toxicity,   etc   ; doxorubicin; neoplasms; oxidative stress; patients;     Show all 5 Subjects
Abstract:
... Doxorubicin (Dox) is a valuable anticancer drug for hematologic and solid tumors. Yet, it can cause multi-organ toxicities in various patients. Since toxicity evaluation is a major criterion to discuss for every experiment, the current mini-review focuses on the toxicity of Dox to multiple organs and suggests the most probable mechanism. Though several mechanisms have been suggested, the role of o ...
DOI:
10.1016/j.lfs.2018.03.023

6. A novel bispecific antibody fusion protein co-targeting EGFR and CD47 with enhanced therapeutic index

Author:
Yang, Yun; Guo, Rui; Chen, Qi; Liu, Youxun; Zhang, Pengfei; Zhang, Ziheng; Chen, Xi; Wang, Tianyun
Source:
Biotechnology letters 2018 v.40 no.5 pp. 7-795
ISSN:
0141-5492
Subject:
toxicity,   etc   ; antibodies; erythrocytes; models; neoplasms; therapeutics;     Show all 6 Subjects
Abstract:
... OBJECTIVE: To promote targeting specificity of anti-CD47 agents, we have constructed a novel bispecific antibody fusion protein against EGFR and CD47, which may minimize the “off-target” effects caused by CD47 expression on red blood cells. RESULTS: The novel bispecific antibody fusion protein, denoted as Bi-SP could simultaneously bind to EGFR and CD47 and exhibited potent phagocytosis-stimulatio ...
DOI:
10.1007/s10529-018-2535-2

7. Using sulfinamides as high oxidation state sulfur reagent for preparation of sulfenamides

Author:
Ma, Long-jun; Li, Guang-xun; Huang, Jin; Zhu, Jin; Tang, Zhuo
Source:
Tetrahedron letters 2018 v.59 pp. 4-1603
ISSN:
0040-4039
Subject:
toxicity,   etc   ; aromatic amines; moieties; oxidation; sulfur;     Show all 5 Subjects
Abstract:
... Traditional preparation of sulfenamides require the use of low oxidation state of sulfur reagent such as RSCl, (RS)2 or RSH, which are toxic, odorous and difficult to deal with due to the harsh reaction conditions. Here high oxidation state of sulfur reagent—aliphatic sulfinamide, were used for preparation of sulfenamide in one step efficiently. Different aromatic amines with all sorts of function ...
DOI:
10.1016/j.tetlet.2018.03.033

8. Detection of synchronized burst firing in cultured human induced pluripotent stem cell-derived neurons using a 4-step method

Author:
Matsuda, N.; Odawara, A.; Katoh, H.; Okuyama, N.; Yokoi, R.; Suzuki, I.
Source:
Biochemical and biophysical research communications 2018 v.497 pp. 7-618
ISSN:
0006-291X
Subject:
toxicity,   etc   ; electrophysiology; humans; neural networks; neurons; researchers;     Show all 6 Subjects
Abstract:
... Human induced pluripotent stem cell-derived neurons are promising for use in toxicity evaluations in nonclinical studies. The multi-electrode array (MEA) assay is used in such evaluation systems because it can measure the electrophysiological function of a neural network noninvasively and with high throughput. Synchronized burst firing (SBF) is the main analytic parameter of pharmacological effect ...
DOI:
10.1016/j.bbrc.2018.02.117

9. Nanomaterial toxicity for plants

Author:
Dev, Atul; Srivastava, AnupKumar; Karmakar, Surajit
Source:
Environmental chemistry letters 2018 v.16 no.1 pp. 16-100
ISSN:
1610-3653
Subject:
toxicity,   etc   ; ecosystems; humans; metabolomics; nanomaterials; proteomics; transcriptomics;     Show all 7 Subjects
Abstract:
... Nanomaterials occur widely in ecosystems as the result of both natural processes and human activities. Reports suggest that altered growth patterns in plants result from interactions of nanomaterials and plants. Plant physiological barriers provide some resistance against nanomaterial toxicity. Plants regulate its cell machinery to overcome nanomaterial-mediated stress. Engineered nanomaterials mo ...
DOI:
10.1007/s10311-017-0667-6

10. Drug delivery systems functionalized with bone mineral seeking agents for bone targeted therapeutics

Author:
Rotman, S.G.; Grijpma, D.W.; Richards, R.G.; Moriarty, T.F.; Eglin, D.; Guillaume, O.
Source:
Journal of controlled release 2018 v.269 pp. 12-99
ISSN:
0168-3659
Subject:
toxicity,   etc   ; drug carriers; drugs; osteomyelitis; osteoporosis; osteosarcoma;     Show all 6 Subjects
Abstract:
... The systemic administration of drugs to treat bone diseases is often associated with poor uptake of the drug in the targeted tissue, potential systemic toxicity and suboptimal efficacy. In order to overcome these limitations, many micro- and nano-sized drug carriers have been developed for the treatment of bone pathologies that exhibit specific affinity for bone. Drug carriers can be functionalize ...
DOI:
10.1016/j.jconrel.2017.11.009

11. Dynamics of Trophic Activity of Leaf-Eating Insects on Birch during Reduction of Emissions from the Middle Ural Copper Smelter

Author:
Belskaya, E.A.
Source:
Russian journal of ecology 2018 v.49 no.1 pp. 6-92
ISSN:
1067-4136
Subject:
toxicity,   etc   ; Betula; emissions; heavy metals; insects; leaves;     Show all 6 Subjects
Abstract:
... The trophic activity of birch leaf-eating insects in background and impact (highly polluted) sites near the Middle Ural Copper Smelter has been recorded in 2008–2015. Reduction of emissions leads to a significant decrease in the concentration of heavy metals in birch leaves, and the existing differences in the proportion of damaged leaves between the background and impact sites are leveling off. A ...
DOI:
10.1134/S1067413617060029

12. Efficient degradation of selected polluting dyes using the tetrahydroxoargentate ion, Ag(OH)4−, in alkaline media

Author:
Zamora-Garcia, Ileana R.; Alatorre-Ordaz, Alejandro; Ibanez, Jorge G.; Torres-Elguera, Julio C.; Wrobel, Kazimierz; Gutierrez-Granados, Silvia
Source:
Chemosphere 2018 v.191 pp. 400-407
ISSN:
0045-6535
Subject:
toxicity,   etc   ; fluorescein; mineralization; oxidation; risk; silver;     Show all 6 Subjects
Abstract:
... The use of soluble and highly oxidizing Ag(III) in the form of the tetrahydroxoargentate ion Ag(OH)4− is reported for the oxidation of surrogate organic recalcitrant dyes (i.e., rhodamine 6G (Rh6G) and fluorescein (Fl)). The possible use of Ag(OH)4− for the treatment of these and other refractory compounds is assessed. Such dyes were selected due to their common occurrence, stability, refractory n ...
DOI:
10.1016/j.chemosphere.2017.10.041

13. Real-time investigation of interactions between nanoparticles and cell membrane model B Biointerfaces

Author:
Wang, Ting; Feng, Zhangqi; Wang, Chu; He, Nongyue
Source:
Colloids and surfaces 2018 v.164 pp. 8-77
ISSN:
0927-7765
Subject:
toxicity; toxicity testing,   etc   ; colloids; flow cytometry; fluorescence emission spectroscopy; lipid bilayers; lipids; models; nanoparticles;     Show all 9 Subjects
Abstract:
... Understanding the internal cellular processes of micron/nanoparticles will be important for particles toxicity studies or drug-delivery systems designing. The details and mechanisms of the cellular up-take process of micron/nano particles can hardly be described in real-time. In this study, cellular internalization of micron/nanoparticles was investigated by fluorescence spectroscopy, flow cytomet ...
DOI:
10.1016/j.colsurfb.2018.01.012

14. Bioelectrochemical biosensor for water toxicity detection: generation of dual signals for electrochemical assay confirmation

Author:
Yang, Yuan; Wang, Yan-Zhai; Fang, Zhen; Yu, Yang-Yang; Yong, Yang-Chun
Source:
Analytical and bioanalytical chemistry 2018 v.410 no.4 pp. 6-1236
ISSN:
1618-2642
Subject:
toxicity; toxicity testing,   etc   ; Shewanella oneidensis; aquatic environment; bioelectrochemistry; biosensors; models; monitoring; risk; toxic substances; water quality;     Show all 11 Subjects
Abstract:
... Toxicity assessment of water is of great important to the safety of human health and to social security because of more and more toxic compounds that are spilled into the aquatic environment. Therefore, the development of fast and reliable toxicity assessment methods is of great interest and attracts much attention. In this study, by using the electrochemical activity of Shewanella oneidensis MR-1 ...
DOI:
10.1007/s00216-017-0656-4

15. Feeding Behavior of an Aquatic Snail as a Simple Endpoint to Assess the Exposure to Cadmium

Author:
Alonso, Álvaro; Valle-Torres, Guillermo
Source:
Bulletin of environmental contamination and toxicology 2018 v.100 no.1 pp. 7-88
ISSN:
0007-4861
Subject:
toxicity; toxicity testing,   etc   ; Potamopyrgus antipodarum; bioassays; cadmium; ecosystems; ecotoxicology; environmental impact; feeding behavior; mortality; snails;     Show all 11 Subjects
Abstract:
... One of the aims of ecotoxicology is the assessment of the effects of chemicals on the ecosystems. Bioassays assessing lethality are frequently used in ecotoxicology, however they usually employ supra-environmental toxic concentrations. Toxicity tests employing behavioral endpoints may present a balance between simplicity (i.e., laboratory bioassays) and complexity (i.e., relevant ecological effect ...
DOI:
10.1007/s00128-017-2230-3

16. Is Caenorhabditis elegans representative of freshwater nematode species in toxicity testing?

Author:
Haegerbaeumer, Arne; Höss, Sebastian; Heininger, Peter; Traunspurger, Walter
Source:
Environmental science and pollution research international 2018 v.25 no.3 pp. 10-2888
ISSN:
0944-1344
Subject:
toxicity; toxicity testing,   etc   ; Caenorhabditis elegans; aqueous solutions; chemical treatment; interspecific variation; metals; models; polycyclic aromatic hydrocarbons;     Show all 9 Subjects
Abstract:
... Multi-species toxicity tests were conducted using a broad range of freshwater nematode species to assess interspecific differences in sensitivity to chemical stress and to compare the toxicity to that on the standard test organism Caenorhabditis elegans. The lethal effects of nine different chemical treatments, including metals and polycyclic aromatic hydrocarbons (PAHs) in single and mixture appl ...
DOI:
10.1007/s11356-017-0714-7

17. Investigation of Acute and Chronic Toxicity Trends of Pesticides Using High-Throughput Bioluminescence Assay Based on the Test Organism Vibrio fischeri

Author:
Westlund, Paul; Nasuhoglu, Deniz; Isazadeh, Siavash; Yargeau, Viviane
Source:
Archives of environmental contamination and toxicology 2018 v.74 no.4 pp. 11-567
ISSN:
0090-4341
Subject:
acute toxicity; chronic toxicity; toxicity testing,   etc   ; Vibrio fischeri; bioluminescence; bioluminescence assay; fungicides; herbicides; mechanism of action; median effective concentration; neonicotinoid insecticides; nontarget organisms; physicochemical properties; structure-activity relationships;     Show all 14 Subjects
Abstract:
... High-throughput acute and chronic toxicity tests using Vibrio fischeri were used to assess the toxicity of a variety of fungicides, herbicides, and neonicotinoids. The use of time points beyond the traditional 30 min of an acute test highlighted the sensitivity and applicability of the chronic toxicity test and indicated that for some compounds toxicity is underestimated using only the acute test. ...
DOI:
10.1007/s00244-017-0483-9

18. Methods Utilizing First-Row Transition Metals in Natural Product Total Synthesis

Author:
Zweig, Joshua E.; Kim, Daria E.; Newhouse, Timothy R.
Source:
Chemical Reviews 2017 v.117 no.18 pp. 11680-11752
ISSN:
1520-6890
Subject:
toxicity,   etc   ; catalysts; transition elements;     Show all 3 Subjects
Abstract:
... First-row transition-metal-mediated reactions constitute an important and growing area of research due to the low cost, low toxicity, and exceptional synthetic versatility of these metals. Currently, there is considerable effort to replace existing precious-metal-catalyzed reactions with first-row analogs. More importantly, there are a plethora of unique transformations mediated by first-row metal ...
DOI:
10.1021/acs.chemrev.6b00833

19. Optimization of SNAP-25-derived peptide substrate for improved detection of botulinum A in the Endopep-MS assay

Author:
Rosen, Osnat; Feldberg, Liron; Dor, Eyal; Gura, Sigalit; Zichel, Ran
Source:
Analytical biochemistry 2017 v.528 pp. 34-37
ISSN:
0003-2697
Subject:
toxicity,   etc   ; botulinum toxin; proteins;     Show all 3 Subjects
Abstract:
... Botulinum neurotoxins (BoNTs) are the most toxic proteins in nature. Endopeptidase-mass-spectrometry (Endopep-MS) is used as a specific and rapid in-vitro assay to detect BoNTs. In this assay, immunocaptured toxin cleaves a serotype-specific-peptide-substrate, and the cleavage products are then detected by MS. Here we describe the design of a new peptide substrate for improved detection of BoNT ty ...
DOI:
10.1016/j.ab.2017.04.012

20. Persistent Mercury Contamination in Shooting Range Soils: The Legacy from Former Primers

Author:
Stauffer, M.; Pignolet, A.; Corcho Alvarado, J. A.
Source:
Bulletin of environmental contamination and toxicology 2017 v.98 no.1 pp. 14-21
ISSN:
0007-4861
Subject:
toxicity,   etc   ; mercury; soil; Switzerland;     Show all 4 Subjects
Abstract:
... Mercury (Hg) compounds were used in the past in primers for rifle and handgun ammunition. Despite its toxicity, little is known about the contamination of shooting-range soils with this metal. We present new data about the Hg contamination of surface soils from numerous shooting ranges of Switzerland. Our study demonstrates that Hg is measurable at high levels in surface soils from the shooting ra ...
DOI:
10.1007/s00128-016-1976-3