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... Allelochemicals sustained-release microspheres (ACs-SMs) exhibited great inhibition effect on algae, however, few studies have focused on ACs-SMs toxicity on invertebrate. In this study, the effects of single high-concentration ACs (15 mg/L, SH-ACs), repeated low-concentration ACs (3 × 5 mg/L, RL-ACs) and ACs-SMs containing 15 mg/L ACs exposure on the ingestion, incorporation, and digestion of Dap ...
toxicity, etc ; Japan; activated sludge; biodegradation; biological treatment; biotransformation; databases; metrology; nitrogen; phosphorus; wastewater; water reuse; water treatment; China; Show all 14 Subjects
Abstract:
... In order to reveal the hotspots and trends of biological water treatment from the perspectives of scientific and technological innovation, both of the bibliometric review and patents analysis were performed in this study. The Web of Science Core Collection database and Derwent Innovation Index database recorded 30023 SCI papers and 50326 patents, respectively were analyzed via information visualiz ...
toxicity, etc ; Danio rerio; adults; bioaccumulation; brain; chemical analysis; flame retardants; histopathology; humans; liver; pollution; progeny; transcription (genetics); China; Show all 14 Subjects
Abstract:
... Many environmental contaminants could be transmitted from parents and generate impairments to their progeny. The 2,4,6-tribromophenol (TBP), a novel brominated flame retardant which has been frequently detected in various organisms, was supposed to be bioaccumulated and intergenerational transmitted in human beings. Previous studies revealed that TBP could disrupt thyroid endocrine system in zebra ...
toxicity; toxicity testing, etc ; cancer therapy; chemistry; glutathione; legumain; neoplasms; radiotherapy; Show all 8 Subjects
Abstract:
... Targeted radionuclide therapy (TRT) has been a promising strategy for cancer therapy, which can inhibit or kill cancer cells by selectively delivering radionuclide to target tissues. Herein, a legumain-targeted therapeutic agent [¹³¹I]MAAN was synthesized that was capable of condensation and self-assembly in response to legumain and glutathione (GSH) in tumor cells to enhance the therapeutic effec ...
toxicity; toxicity testing, etc ; biphenyl; homeostasis; metabolites; metabolomics; microplastics; polychlorinated biphenyls; Show all 8 Subjects
Abstract:
... In the past few decades, the toxic effects of environmental pollutants on non-target organisms have received more and more attention. As a new omics technology, metabolomics can clarify the metabolic homeostasis of the organism at the overall level by studying the changes in the relative contents of endogenous metabolites in the organism. Recently, a large number of studies have used metabolomics ...
toxicity, etc ; adsorbents; adsorption; chromium; ecosystems; formic acid; heavy metals; human health; pH; pollution; porosity; surface area; wastewater; water quality; China; Show all 15 Subjects
Abstract:
... Zr-based metal-organic frameworks (MOFs) have been developed in recent years to treat heavy metals, e.g. hexavalent chromium Cr⁶⁺ pollution, which damages the surrounding ecosystem and threaten human health. This kind of MOF is stable and convenient to prepare, but has the disadvantage of low adsorption capacity, limiting its wide application. To this end, a novel formic acid and amino modified MO ...
toxicity; toxicity testing, etc ; Vibrio fischeri; bioluminescence; cations; ecotoxicology; electrochemistry; lithium; pollution; research; Show all 10 Subjects
Abstract:
... The applicability of ionic liquids (ILs) has increased over the last years, and even new opportunities are becoming a reality, i.e. mixtures of pure IL and inorganic salt as electrolytes for smart electrochemical devices, yet the effects on the environment are almost unknown. In this work, the ecotoxicity of two pure protic ILs (Ethylammonium nitrate and Ethylimidazolium nitrate) and two pure apro ...
toxicity, etc ; DNA damage; Drosophila melanogaster; cell viability; dose response; eclosion; fat body; fecundity; genes; hemocytes; metallothionein; nanosilver; pupation; sequence analysis; China; Show all 15 Subjects
Abstract:
... The widely use of silver nanoparticles (AgNPs) as antimicrobial agents gives rise to potential environmental risks. AgNPs exposure have been reported to cause toxicity in animals. Nevertheless, the known mechanisms of AgNPs toxicity are still limited. In this study, we systematically investigated the toxicity of AgNPs exposure using Drosophila melanogaster. We show here that AgNPs significantly de ...
toxicity; toxicity testing, etc ; antidepressants; benzene; ecology; electrochemistry; environmental technology; human health; mineralization; oxidation; Show all 10 Subjects
Abstract:
... The presence of venlafaxine, one of the popular antidepressants, in environmental aquatic media has become a rising issue and potential threat to global ecology and human health. However, advanced technologies for efficient venlafaxine degradation remain underdeveloped. Herein, we propose to use chloride-mediated electrochemical degradation to efficiently remove venlafaxine in aqueous media. The d ...
... Vacuum ultraviolet (VUV) photolysis is recognized as an environmental-friendly treatment process. Nitrate (NO₃⁻) and natural organic matter (NOM) are widely present in water source. We investigated trichloronitromethane (TCNM) formation during chlorination after VUV photolysis, because TCNM is an unregulated highly toxic disinfection byproduct. In this study: (1) we found reactive nitrogen species ...
toxicity, etc ; Danio rerio; agonists; antagonists; bioassays; calcium; cardiomyocytes; cardiotoxicity; electron transport chain; gene expression; heart rate; human health; mepanipyrim; mitochondria; viticulture; China; Show all 16 Subjects
Abstract:
... The wide use of pesticides has seriously threatened human health and the survival of beneficial organisms. The fungicide mepanipyrim is widely used in viticulture practices. Studies of mepanipyrim-induced toxicity in organisms are still scarce, especially studies on cardiotoxicity. In this study, we aimed to investigate mepanipyrim-induced cardiotoxicity in zebrafish (Danio rerio) larvae. We found ...
... This study comprehensively investigated arsenic's enrichment, distribution, and characteristics in tailings. XRD and SEM-EDS characterized the phase and morphology of tailings from various smelting processes. At the same time, the embedding characteristics of arsenic in the ore phase were analyzed by EPMA. The differences between arsenic's leading ore phase carriers in different recovery processes ...
... Bacterial microcompartments (BMCs) are protein-encapsulated compartments found across at least 23 bacterial phyla. BMCs contain a variety of metabolic processes that share the commonality of toxic or volatile intermediates, oxygen-sensitive enzymes and cofactors, or increased substrate concentration for magnified reaction rates. These compartmentalized reactions have been computationally modeled t ...
... Natural products have complex chemical structures and exhibit diverse bioactivities. To harness these high-value natural compounds, robust approaches are required for their rapid and sustainable production. Recently, cell-free systems as one promising solution have been applied to produce natural products by reconstitution of their entire biosynthetic pathways in vitro. Here, we highlight recent a ...
... Irinotecan-loaded solid lipid nanoparticles (IRI-SLNs) was formulated and tested for its potential activity against colon cancer. IRI-SLNs were prepared by applying the principles of DoE. Nanoparticles were further surface modified using chitosan. Characterizations such as size, poly-dispersity, surface charge, morphology, entrapment, drug release pattern, cytotoxicity were conducted. In-vivo stud ...
... Propiconazole (PRO) is a triazole fungicide that is frequently detected in the water. In this study, we investigated the kinetics and degradation mechanism of PRO during the UV photolysis and UV/H₂O₂ processes. PRO was removed by the pseudo-first-order kinetics in both processes. The removal of PRO was enhanced by increasing H₂O₂ concentration in the UV/H₂O₂ process. The highest removal under neut ...
acute oral toxicity; toxicity testing, etc ; adverse effects; body weight; bromelains; histopathology; kidneys; liver; mortality; protein hydrolysates; Show all 10 Subjects
Abstract:
... Despite green peas protein hydrolysate benefits, very few studies have described the potential toxicity. The acute oral toxicity of green peas protein which hydrolyzed by bromelain at a single dose of 5000 mg/kg BW has been evaluated in Swiss Webster mice and did not produce treatment-related signs of toxicity or mortality in any of the animals tested during the 14-day observation period. The pres ...
toxicity, etc ; aziridines; catalysts; catalytic activity; Show all 4 Subjects
Abstract:
... Converting CS₂ into high-value products is an emerging and effective strategy for disposing of CS₂, which can avoid generating various toxic pollutants caused by the traditional method of incinerating CS₂. However, there are great challenges involved in searching for novel catalysts to obtain highly effective CS₂ conversion with aziridines under mild conditions. Herein, a novel MOF (1) assembled f ...
... A regioselective Pd-catalyzed hydrocarboxylation of terminal olefins with HCOOH is described. A wide variety of branched carboxylic acids can readily be obtained with high regioselectivities under mild reaction conditions. The reaction is operationally simple and requires no handling of toxic CO. The ligand and LiCl are important factors for reaction reactivity and selectivity. ...
toxicity, etc ; amides; biphenyl; cycloaddition reactions; Show all 4 Subjects
Abstract:
... Tetrazoles were effectively synthesized from amides using diphenyl phosphorazidate or bis(p-nitrophenyl) phosphorazidate in the presence of aromatic bases. Various amides underwent the proposed cycloaddition reaction to provide the corresponding tetrazoles. Studies on the racemization of chiral substrates were also performed. Overall, the proposed synthesis method enables the preparation of 1,5-di ...