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triterpenoids, etc ; Uncaria; macrophages; research; spectroscopy; Show all 5 Subjects
Abstract:
... One novel pentacyclic triterpene, 24-dimethoxymethyl-3β,6β,19α- trihydroxy −12-en-28-oic acid (1), along with six known compounds 2–7, were isolated from the canes of Uncaria sessilifructus Roxb. Their structures were determined according to spectroscopic and spectrometric analysis. The anti-inflammatory activities of the isolated compounds (1–7) were scanned against NO production in LPS-activated ...
triterpenoids, etc ; Favolaschia; plant biochemistry; stereochemistry; Show all 4 Subjects
Abstract:
... A bis-epoxide ergostane triterpenoid (favolon), its undescribed derivative (favolon C), and a biogenetically related norergostane (laschiatrion) were isolated from the cultures of basidiomycete Favolaschia calocera BCC 36684. The stereochemistry of favolon was also determined for the first time. Additionally, we propose the revision of the C-24 configuration of laschiatrion to 24R. ...
Drielli Rhiane P. Colhado Arêas; Márcia R. P. Cabral; Anderson V. G. Ramos; Juliana L. B. Peixoto; Marta R. Barrotto do Carmo; Debora C. Baldoqui; Carla Porto; Maria Helena Sarragiotto
triterpenoids, etc ; Asteraceae; flavonoids; research; sesquiterpenoid lactones; Show all 5 Subjects
Abstract:
... Chemical investigation of Lessingianthus brevifolius (Less.) H.Rob. aerial parts resulted in the isolation of the hirsutinolide-type sesquiterpene lactones piptocarphol, spicatolide D, piptocarphin D and 8α-acetoxy-10α-hydroxy-13-O-methylhirsutinolide, and also of a cadinanolide identified as 13-O-methylvernojalcanolide 8-O-acetate. Flavonoids, triterpenes and chlorogenic acids were also isolated. ...
triterpenoids, etc ; Schisandra chinensis; lignans; research; spectroscopy; Show all 5 Subjects
Abstract:
... Three new highly modified lanostane triterpenoids schisanchinlactone A-C (1–3), together with six known compounds (4–9) were isolated from the stems and leaves of Schisandra chinensis. Their structures were established by extensive spectroscopic analyses. Compounds 7 and 8 showed significant inhibition of Cdc25A phosphatase with inhibitory rates of 85.5% and 98.1%, respectively, at the concentrati ...
triterpenoids, etc ; Juglans mandshurica; cytotoxicity; research; spectroscopy; walnuts; Show all 6 Subjects
Abstract:
... Two new dammarane-type triterpenoids, dammar-3α,12(R),20(S)-triol-12,32(R);20,32-diepoxy-25-methy-25-en-tridecacyclic ether (1) and (23E)-12β,20(R),25(S),26-tetrahydroxydammar-23-en-3-one (2) were isolated from the green walnut husks of Juglans mandshurica Maxim together with six known compounds. Their structures were elucidated through extensive spectroscopic analyses and by comparison with the l ...
triterpenoids, etc ; Sapindales; chemical composition; epicuticular wax; hydrophobicity; transpiration; Show all 6 Subjects
Abstract:
... Cuticular waxes play an important role in plant survival in terrestrial environments. They are part of the cuticle and form a hydrophobic barrier associated with a decline in water loss through cuticular transpiration. Data on the chemical and morphological composition of cuticular waxes in Sapindales have been collected for more than 5th years. The present review compiles the data published for t ...
triterpenoids, etc ; Ganoderma; antimalarials; derivatization; mass spectrometry; plant biochemistry; Show all 6 Subjects
Abstract:
... In the quest for medicinally active compounds in mushrooms of the genus Ganoderma, eleven undescribed lanostane triterpenoids, including a novel chlorinated derivative, i.e., (20S,24E)-21-chloro-15β,20,29-trihydroxy-3,7,11-trioxolanosta-8,24-dien-26-oic acid, were isolated from artificially cultivated fruiting bodies of the basidiomycete Ganoderma mbrekobenum. The structures were elucidated on the ...
triterpenoids, etc ; Acrocomia aculeata; biochemical pathways; biosynthesis; energy; research; stereochemistry; sterols; Show all 8 Subjects
Abstract:
... The new compound totaiol (isolated from Acrocomia totai) was misnamed as a hopane-type triterpene. Considering its biosynthesis, it could be considered as an intermediate of other triterpenes isolated from the same source (following a sterol folding of 2,3-squalene oxide). In contrast, hopane-type triterpenes follow a different biosynthetic route (non-sterol folding of 2,3-squalene oxide). The ste ...
triterpenoids, etc ; Daphniphyllum; X-ray diffraction; lignans; plant biochemistry; spectral analysis; China; Show all 7 Subjects
Abstract:
... The fruits, twigs and leaves of Daphniphyllum oldhamii (Hemsl.) K. Rosenthal, collected from Longshan County, Hunan Province, China, were chemically investigated. Three undescribed daphniphyllum alkaloids, namely longshanoldhamines A‒C, and six known related ones have been isolated from the fruits, whereas two undescribed triterpenoids and one undescribed lignan, along with six known triterpenoids ...
triterpenoids, etc ; Irpex lacteus; fungi; probability; research; sesquiterpenoids; solid state fermentation; spectral analysis; Show all 8 Subjects
Abstract:
... A new tremulane sesquiterpene, lactedine (1), along with seven known tremulane sesquiterpenes (2–8) and one known triterpene (9) were isolated from the fungus Irpex lacteus. Their structures were established on the basis of extensive spectroscopic data and DP4+ probability analyses. ...
triterpenoids, etc ; Dracocephalum moldavica; chemotaxonomy; ecology; glycosides; lignans; monoterpenoids; norisoprenoids; phytochemicals; spectral analysis; Show all 10 Subjects
Abstract:
... A phytochemical investigation of the aerial parts of Dracocephalum moldavica L. (Lamiaceae) led to the isolation and characterization of 30 compounds, including eight lignans (1–8), seven phenols (9–15), five triterpenoids (16–20), four monoterpenoids (21–24), four glycosides (25–28) and two megastigmanes (29 and 30). The structures of these compounds were determined by spectroscopic data analysis ...
triterpenoids, etc ; cell senescence; colorectal neoplasms; food chemistry; neoplasm progression; therapeutics; transcription factors; Show all 7 Subjects
Abstract:
... The induction of cellular senescence is considered as a potent strategy to suppress cancer progression. Cucurbitacin E (CE) belongs to the triterpenoids and has received substantial attention for its antineoplastic property. However, the function of CE on cellular senescence remained elusive. Herein, we revealed that CE significantly induced cellular senescence in colorectal cancer (CRC) cells. Th ...
triterpenoids, etc ; Poria; chemometrics; fungi; least squares; near-infrared spectroscopy; polysaccharides; water solubility; Show all 8 Subjects
Abstract:
... Poria cocos (PC) is an important fungus with high medicinal and nutritional values. However, the quality of PC is heavily dependent on multiple factors in the cultivation regions. Traditional methods are not able to perform quality evaluation for this fungus in a short time, and a new method is needed for rapid quality assessment. Here, we used near-infrared (NIR) spectroscopy combined with chemom ...
triterpenoids, etc ; Xanthium strumarium; cell cycle checkpoints; cytotoxicity; death; interphase; phytochemicals; spectral analysis; Show all 8 Subjects
Abstract:
... Eight pentacyclic triterpenoids including two new ones (1, 2) were isolated from the fruits of Xanthium strumarium. Their structures were elucidated by extensive spectroscopic analysis. All isolates were evaluated for in vitro cytotoxic activity on HepG2, A549, HCT116 and SW480 cancer cells. Among them, the new compound 2 was found to exhibit significant cytotoxic activity on A549, HCT116 and SW48 ...
triterpenoids, etc ; Calophyllum; coumarins; cytotoxicity; hepatocytes; human cell lines; liver; research; stigmasterol; xanthones; Show all 10 Subjects
Abstract:
... Species from the Genus Calophyllum are rich source for bioactive phenolic compounds such as coumarins and xanthones. Phytochemical study carried out on the plant, Calophyllum macrocarpum has led to the isolation of three known prenylated xanthones, ananixanthone (1), trapezifolixanthone (2) and 8-deoxygartanin (3) with two common triterpenoids, stigmasterol (4), and friedelin (5). The structures o ...
triterpenoids, etc ; Paeonia delavayi; Paeonia suffruticosa; glucagon-like peptide 1; hydrogen; hydrophobicity; plant biochemistry; Show all 7 Subjects
Abstract:
... Three new nor-oleanane triterpenoids, paeonenoides I-K (1-3), together with 13 known triterpenoids including nor-oleanane, oleanane, ursane, and cycloartane types, were isolated from the leaves of Paeonia suffruticosa and P. delavayi. The structures of the new compounds were elucidated with the aid of HRESIMS, 1D and 2D NMR, IR, and [α]D spectroscopic methods. Nine compounds (5-6, 8-11, 13-14 and ...
triterpenoids, etc ; antioxidants; coumarins; cytotoxicity; diterpenoids; endophytes; meroterpenoids; monoterpenoids; plant biochemistry; polyketides; quinones; sesquiterpenoids; Show all 12 Subjects
Abstract:
... Plant endophytes have been considered as novel sources of naturally occurring compounds with various biological activities, including cytotoxic, antimicrobial, anti-inflammatory, anticancer, herbicides, antileishmanial and antioxidant. A variety of specialised products, comprising terpenoids, alkaloids, polyketides, phenolic compounds, coumarins, and quinone derivatives have been reported from var ...
triterpenoids, etc ; chemical composition; cold storage; epicuticular wax; fruits; gene expression; genes; kumquats; stigmasterol; Show all 9 Subjects
Abstract:
... The aim of this paper was to identify changes in the crystal morphology, chemical composition and key gene expression of 'Suichuan' kumquat cuticular waxes after hot water dipping treatment (HWD), before and after cold storage, as well as the relationship of cuticular waxes with storage performance improvement. Scanning electron microscopy (SEM) showed a rearrangement of epicuticular wax layers af ...
triterpenoids, etc ; Asteroidea; Holothuria; cytotoxicity; glycosides; humans; melanoma; metabolites; mice; neoplastic cell transformation; sugars; Show all 11 Subjects
Abstract:
... Sea stars or starfish (class Asteroidea) and holothurians or sea cucumbers (class Holothuroidea), belonging to the phylum Echinodermata (echinoderms), are characterized by different sets of glycosidic metabolites: the steroid type in starfish and the triterpene type in holothurians. However, herein we report the isolation of eight new triterpene glycosides, pacificusosides D–K (1–3, 5–9) along wit ...
triterpenoids, etc ; Cynomorium; cell death; functional foods; spectral analysis; structure-activity relationships; traditional medicine; Show all 7 Subjects
Abstract:
... Cynomorium coccineum subsp. songaricum (Rupr.) J. Leonard has been widely used as a Chinese herbal remedy or a functional food for treating symptoms of aging or neurodegenerative diseases. A further investigation on the finding of active constituents led to the isolation and identification of four previously undescribed triterpenoids, together with 20 known compounds. Their structures were elucida ...