U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Subject "triterpenoids" Remove constraint Subject: "triterpenoids"
Start Over

Search

4,214  Search Results

« Previous | 1 - 20 of 4,214 |
Number of results to display per page

Search Results

1. A novel pentacyclic triterpene from the canes of Uncaria sessilifructus (Rubiaceae)

Author:
Qingfei Fan; Zhi Na; Kailong Ji; Pianchou Gongpan; Lan Zhou; Wenqian He; Fengmei Huang; Huabin Hu; Qishi Song
Source:
Natural product research 2022 v.36 no.2 pp. 668-673
ISSN:
1478-6427
Subject:
triterpenoids,   etc   ; Uncaria; macrophages; research; spectroscopy;     Show all 5 Subjects
Abstract:
... One novel pentacyclic triterpene, 24-dimethoxymethyl-3β,6β,19α- trihydroxy −12-en-28-oic acid (1), along with six known compounds 2–7, were isolated from the canes of Uncaria sessilifructus Roxb. Their structures were determined according to spectroscopic and spectrometric analysis. The anti-inflammatory activities of the isolated compounds (1–7) were scanned against NO production in LPS-activated ...
DOI:
10.1080/14786419.2020.1795856

2. Ergostane triterpenoids from the cultures of basidiomycete Favolaschia calocera BCC 36684 and stereochemical elucidation of favolon

Author:
Somporn Palasarn; Kamolphan Intereya; Thitiya Boonpratuang; Chawanee Thongpanchang; Masahiko Isaka
Source:
Phytochemistry letters 2022 v.47 pp. 168-173
ISSN:
1874-3900
Subject:
triterpenoids,   etc   ; Favolaschia; plant biochemistry; stereochemistry;     Show all 4 Subjects
Abstract:
... A bis-epoxide ergostane triterpenoid (favolon), its undescribed derivative (favolon C), and a biogenetically related norergostane (laschiatrion) were isolated from the cultures of basidiomycete Favolaschia calocera BCC 36684. The stereochemistry of favolon was also determined for the first time. Additionally, we propose the revision of the C-24 configuration of laschiatrion to 24R. ...
DOI:
10.1016/j.phytol.2022.01.002

3. Chemical constituents and dereplication study of Lessingianthus brevifolius (Less.) H.Rob. (Asteraceae) by UHPLC-HRMS and molecular networking

Author:
Drielli Rhiane P. Colhado Arêas; Márcia R. P. Cabral; Anderson V. G. Ramos; Juliana L. B. Peixoto; Marta R. Barrotto do Carmo; Debora C. Baldoqui; Carla Porto; Maria Helena Sarragiotto
Source:
Natural product research 2022 v.36 no.7 pp. 1889-1892
ISSN:
1478-6427
Subject:
triterpenoids,   etc   ; Asteraceae; flavonoids; research; sesquiterpenoid lactones;     Show all 5 Subjects
Abstract:
... Chemical investigation of Lessingianthus brevifolius (Less.) H.Rob. aerial parts resulted in the isolation of the hirsutinolide-type sesquiterpene lactones piptocarphol, spicatolide D, piptocarphin D and 8α-acetoxy-10α-hydroxy-13-O-methylhirsutinolide, and also of a cadinanolide identified as 13-O-methylvernojalcanolide 8-O-acetate. Flavonoids, triterpenes and chlorogenic acids were also isolated. ...
DOI:
10.1080/14786419.2020.1813132

4. Triterpenoids and lignans from Schisandra chinensis and their inhibition activities of Cdc25A/B phosphatases

Author:
Qian-Qian Zhao; Wen-Jun Wei; Ya Li; Kun Gao
Source:
Natural product research 2022 v.36 no.3 pp. 754-759
ISSN:
1478-6427
Subject:
triterpenoids,   etc   ; Schisandra chinensis; lignans; research; spectroscopy;     Show all 5 Subjects
Abstract:
... Three new highly modified lanostane triterpenoids schisanchinlactone A-C (1–3), together with six known compounds (4–9) were isolated from the stems and leaves of Schisandra chinensis. Their structures were established by extensive spectroscopic analyses. Compounds 7 and 8 showed significant inhibition of Cdc25A phosphatase with inhibitory rates of 85.5% and 98.1%, respectively, at the concentrati ...
DOI:
10.1080/14786419.2020.1802268

5. Two new dammarane-type triterpenoids from the green walnut husks of Juglans mandshurica Maxim

Author:
Yuan-Yuan Zhou; Hui-Rui Gao; Hong-Juan Song; Dan-Da Ma; Xiao-Juan Zhang; Yan-Ping Sun; Yan Liu; Xiao-Li Wang; Bing-You Yang; Hai-Xue Kuang
Source:
Natural product research 2022 v.36 no.7 pp. 1812-1819
ISSN:
1478-6427
Subject:
triterpenoids,   etc   ; Juglans mandshurica; cytotoxicity; research; spectroscopy; walnuts;     Show all 6 Subjects
Abstract:
... Two new dammarane-type triterpenoids, dammar-3α,12(R),20(S)-triol-12,32(R);20,32-diepoxy-25-methy-25-en-tridecacyclic ether (1) and (23E)-12β,20(R),25(S),26-tetrahydroxydammar-23-en-3-one (2) were isolated from the green walnut husks of Juglans mandshurica Maxim together with six known compounds. Their structures were elucidated through extensive spectroscopic analyses and by comparison with the l ...
DOI:
10.1080/14786419.2020.1818233

6. A comprehensive review of the chemical composition and epicuticular wax morphology of the cuticle in Sapindales

Author:
Lucas Paradizo Roma; Déborah Yara A. C. Santos
Source:
Revista brasileira de botânica 2022 v.45 no.1 pp. 5-14
ISSN:
1806-9959
Subject:
triterpenoids,   etc   ; Sapindales; chemical composition; epicuticular wax; hydrophobicity; transpiration;     Show all 6 Subjects
Abstract:
... Cuticular waxes play an important role in plant survival in terrestrial environments. They are part of the cuticle and form a hydrophobic barrier associated with a decline in water loss through cuticular transpiration. Data on the chemical and morphological composition of cuticular waxes in Sapindales have been collected for more than 5th years. The present review compiles the data published for t ...
DOI:
10.1007/s40415-021-00723-x

7. Lanostane triterpenoids from cultivated fruiting bodies of basidiomycete Ganoderma mbrekobenum

Author:
Arunrat Yangchum; Ryoma Fujii; Wilunda Choowong; Pranee Rachtawee; Maneerat Pobkwamsuk; Thitiya Boonpratuang; Seiji Mori; Masahiko Isaka
Source:
Phytochemistry 2022 v.196 pp. 113075
ISSN:
0031-9422
Subject:
triterpenoids,   etc   ; Ganoderma; antimalarials; derivatization; mass spectrometry; plant biochemistry;     Show all 6 Subjects
Abstract:
... In the quest for medicinally active compounds in mushrooms of the genus Ganoderma, eleven undescribed lanostane triterpenoids, including a novel chlorinated derivative, i.e., (20S,24E)-21-chloro-15β,20,29-trihydroxy-3,7,11-trioxolanosta-8,24-dien-26-oic acid, were isolated from artificially cultivated fruiting bodies of the basidiomycete Ganoderma mbrekobenum. The structures were elucidated on the ...
DOI:
10.1016/j.phytochem.2021.113075

8. Totaianes, a new type of triterpenes (Comments on the article “Antiproliferative activity and energy calculations of a new triterpene isolated from the palm tree Acrocomia totai”)

Author:
Fabiola A. López-Huerta; Guillermo Delgado
Source:
Natural product research 2022 v.36 no.2 pp. 601-604
ISSN:
1478-6427
Subject:
triterpenoids,   etc   ; Acrocomia aculeata; biochemical pathways; biosynthesis; energy; research; stereochemistry; sterols;     Show all 8 Subjects
Abstract:
... The new compound totaiol (isolated from Acrocomia totai) was misnamed as a hopane-type triterpene. Considering its biosynthesis, it could be considered as an intermediate of other triterpenes isolated from the same source (following a sterol folding of 2,3-squalene oxide). In contrast, hopane-type triterpenes follow a different biosynthetic route (non-sterol folding of 2,3-squalene oxide). The ste ...
DOI:
10.1080/14786419.2020.1793151

9. Chemical and biological studies of Daphniphyllum oldhamii from Hunan Province, China

Author:
Yi Chen; Shou-Mao Shen; Min Yang; Ming-Zhi Su; Xiao-Ming Wang; Yue-Wei Guo
Source:
Phytochemistry 2022 v.199 pp. 113170
ISSN:
0031-9422
Subject:
triterpenoids,   etc   ; Daphniphyllum; X-ray diffraction; lignans; plant biochemistry; spectral analysis; China;     Show all 7 Subjects
Abstract:
... The fruits, twigs and leaves of Daphniphyllum oldhamii (Hemsl.) K. Rosenthal, collected from Longshan County, Hunan Province, China, were chemically investigated. Three undescribed daphniphyllum alkaloids, namely longshanoldhamines A‒C, and six known related ones have been isolated from the fruits, whereas two undescribed triterpenoids and one undescribed lignan, along with six known triterpenoids ...
DOI:
10.1016/j.phytochem.2022.113170

10. A new tremulane sesquiterpene from Irpex lacteus by solid-state fermentation

Author:
Cheng-Tong Sun; Jia-Peng Wang; Yan Shu; Xue-Yun Cai; Jun-Tao Hu; Sheng-Qi Zhang; Le Cai; Zhong-Tao Ding
Source:
Natural product research 2022 v.36 no.3 pp. 862-867
ISSN:
1478-6427
Subject:
triterpenoids,   etc   ; Irpex lacteus; fungi; probability; research; sesquiterpenoids; solid state fermentation; spectral analysis;     Show all 8 Subjects
Abstract:
... A new tremulane sesquiterpene, lactedine (1), along with seven known tremulane sesquiterpenes (2–8) and one known triterpene (9) were isolated from the fungus Irpex lacteus. Their structures were established on the basis of extensive spectroscopic data and DP4+ probability analyses. ...
DOI:
10.1080/14786419.2020.1806272

11. Chemical constituents from Dracocephalum moldavica L. and their chemotaxonomic significance

Author:
Jiaming Wang; Jinfeng Sun; Mengjie Wang; Huiqiong Cui; Wei Zhou; Gao Li
Source:
Biochemical systematics and ecology 2022 v.102 pp. 104422
ISSN:
0305-1978
Subject:
triterpenoids,   etc   ; Dracocephalum moldavica; chemotaxonomy; ecology; glycosides; lignans; monoterpenoids; norisoprenoids; phytochemicals; spectral analysis;     Show all 10 Subjects
Abstract:
... A phytochemical investigation of the aerial parts of Dracocephalum moldavica L. (Lamiaceae) led to the isolation and characterization of 30 compounds, including eight lignans (1–8), seven phenols (9–15), five triterpenoids (16–20), four monoterpenoids (21–24), four glycosides (25–28) and two megastigmanes (29 and 30). The structures of these compounds were determined by spectroscopic data analysis ...
DOI:
10.1016/j.bse.2022.104422

12. Cucurbitacin E Triggers Cellular Senescence in Colon Cancer Cells via Regulating the miR-371b-5p/TFAP4 Signaling Pathway

Author:
Peng Yang; Qing Lian; Rong Fu; Guo-bin Ding; Sajid Amin; Zongwei Li; Zhuoyu Li
Source:
Journal of agricultural and food chemistry 2022 v.70 no.9 pp. 2936-2947
ISSN:
1520-5118
Subject:
triterpenoids,   etc   ; cell senescence; colorectal neoplasms; food chemistry; neoplasm progression; therapeutics; transcription factors;     Show all 7 Subjects
Abstract:
... The induction of cellular senescence is considered as a potent strategy to suppress cancer progression. Cucurbitacin E (CE) belongs to the triterpenoids and has received substantial attention for its antineoplastic property. However, the function of CE on cellular senescence remained elusive. Herein, we revealed that CE significantly induced cellular senescence in colorectal cancer (CRC) cells. Th ...
DOI:
10.1021/acs.jafc.1c07952

13. Determination of Cultivation Regions and Quality Parameters of Poria cocos by Near-Infrared Spectroscopy and Chemometrics

Author:
Jing Xie; Jianhua Huang; Guangxi Ren; Jian Jin; Lin Chen; Can Zhong; Yuan Cai; Hao Liu; Rongrong Zhou; Yuhui Qin; Shuihan Zhang
Source:
Foods 2022 v.11 no.6 pp. -
ISSN:
2304-8158
Subject:
triterpenoids,   etc   ; Poria; chemometrics; fungi; least squares; near-infrared spectroscopy; polysaccharides; water solubility;     Show all 8 Subjects
Abstract:
... Poria cocos (PC) is an important fungus with high medicinal and nutritional values. However, the quality of PC is heavily dependent on multiple factors in the cultivation regions. Traditional methods are not able to perform quality evaluation for this fungus in a short time, and a new method is needed for rapid quality assessment. Here, we used near-infrared (NIR) spectroscopy combined with chemom ...
DOI:
10.3390/foods11060892

14. Phytochemical investigation of the fruits of Xanthium strumarium and their cytotoxic activity

Author:
Xiang-Wei Xu; Yi-Yuan Xi; Jun Chen; Feng Zhang; Ju-Jia Zheng; Peng-Hai Zhang
Source:
Natural medicines 2022 v.76 no.2 pp. 468-475
ISSN:
1340-3443
Subject:
triterpenoids,   etc   ; Xanthium strumarium; cell cycle checkpoints; cytotoxicity; death; interphase; phytochemicals; spectral analysis;     Show all 8 Subjects
Abstract:
... Eight pentacyclic triterpenoids including two new ones (1, 2) were isolated from the fruits of Xanthium strumarium. Their structures were elucidated by extensive spectroscopic analysis. All isolates were evaluated for in vitro cytotoxic activity on HepG2, A549, HCT116 and SW480 cancer cells. Among them, the new compound 2 was found to exhibit significant cytotoxic activity on A549, HCT116 and SW48 ...
DOI:
10.1007/s11418-021-01588-w

15. Phytochemicals from Calophyllum macrocarpum Hook.f. and its cytotoxic activities

Author:
Thiruventhan Karunakaran; Noor Syarafana Firouz; Rameshkumar Santhanam; Vivien Yi Mian Jong
Source:
Natural product research 2022 v.36 no.2 pp. 654-659
ISSN:
1478-6427
Subject:
triterpenoids,   etc   ; Calophyllum; coumarins; cytotoxicity; hepatocytes; human cell lines; liver; research; stigmasterol; xanthones;     Show all 10 Subjects
Abstract:
... Species from the Genus Calophyllum are rich source for bioactive phenolic compounds such as coumarins and xanthones. Phytochemical study carried out on the plant, Calophyllum macrocarpum has led to the isolation of three known prenylated xanthones, ananixanthone (1), trapezifolixanthone (2) and 8-deoxygartanin (3) with two common triterpenoids, stigmasterol (4), and friedelin (5). The structures o ...
DOI:
10.1080/14786419.2020.1795658

16. Antidiabetic triterpenoids from the leaves of Paeonia suffruticosa and Paeonia delavayi

Author:
Qian Huang; Yang Pan; Sheng-Li Wu; Xiao-Yan Huang; Jing Hu; Yun-Bao Ma; Xue-Mei Zhang; Chang-An Geng
Source:
Phytochemistry letters 2022 v.48 pp. 87-93
ISSN:
1874-3900
Subject:
triterpenoids,   etc   ; Paeonia delavayi; Paeonia suffruticosa; glucagon-like peptide 1; hydrogen; hydrophobicity; plant biochemistry;     Show all 7 Subjects
Abstract:
... Three new nor-oleanane triterpenoids, paeonenoides I-K (1-3), together with 13 known triterpenoids including nor-oleanane, oleanane, ursane, and cycloartane types, were isolated from the leaves of Paeonia suffruticosa and P. delavayi. The structures of the new compounds were elucidated with the aid of HRESIMS, 1D and 2D NMR, IR, and [α]D spectroscopic methods. Nine compounds (5-6, 8-11, 13-14 and ...
DOI:
10.1016/j.phytol.2022.02.009

17. Bioactive terpenoids derived from plant endophytic fungi: An updated review (2011–2020)

Author:
Bahman Zamani Amirzakariya; Abolfazl Shakeri
Source:
Phytochemistry 2022 v.197 pp. 113130
ISSN:
0031-9422
Subject:
triterpenoids,   etc   ; antioxidants; coumarins; cytotoxicity; diterpenoids; endophytes; meroterpenoids; monoterpenoids; plant biochemistry; polyketides; quinones; sesquiterpenoids;     Show all 12 Subjects
Abstract:
... Plant endophytes have been considered as novel sources of naturally occurring compounds with various biological activities, including cytotoxic, antimicrobial, anti-inflammatory, anticancer, herbicides, antileishmanial and antioxidant. A variety of specialised products, comprising terpenoids, alkaloids, polyketides, phenolic compounds, coumarins, and quinone derivatives have been reported from var ...
DOI:
10.1016/j.phytochem.2022.113130

18. Changes in the crystal morphology, chemical composition and key gene expression of 'Suichuan' kumquat cuticular waxes after hot water dipping

Author:
Li Yang; Li Qiu; Dechun Liu; Liuqing Kuang; Wei Hu; Yong Liu
Source:
Scientia horticulturae 2022 v.293 pp. 110753
ISSN:
0304-4238
Subject:
triterpenoids,   etc   ; chemical composition; cold storage; epicuticular wax; fruits; gene expression; genes; kumquats; stigmasterol;     Show all 9 Subjects
Abstract:
... The aim of this paper was to identify changes in the crystal morphology, chemical composition and key gene expression of 'Suichuan' kumquat cuticular waxes after hot water dipping treatment (HWD), before and after cold storage, as well as the relationship of cuticular waxes with storage performance improvement. Scanning electron microscopy (SEM) showed a rearrangement of epicuticular wax layers af ...
DOI:
10.1016/j.scienta.2021.110753

19. In Vitro Anticancer and Cancer-Preventive Activity of New Triterpene Glycosides from the Far Eastern Starfish Solaster pacificus

Author:
Timofey V. Malyarenko; Olesya S. Malyarenko; Alla A. Kicha; Anatoly I. Kalinovsky; Pavel S. Dmitrenok; Natalia V. Ivanchina
Source:
Marine drugs 2022 v.20 no.3 pp. -
ISSN:
1660-3397
Subject:
triterpenoids,   etc   ; Asteroidea; Holothuria; cytotoxicity; glycosides; humans; melanoma; metabolites; mice; neoplastic cell transformation; sugars;     Show all 11 Subjects
Abstract:
... Sea stars or starfish (class Asteroidea) and holothurians or sea cucumbers (class Holothuroidea), belonging to the phylum Echinodermata (echinoderms), are characterized by different sets of glycosidic metabolites: the steroid type in starfish and the triterpene type in holothurians. However, herein we report the isolation of eight new triterpene glycosides, pacificusosides D–K (1–3, 5–9) along wit ...
DOI:
10.3390/md20030216

20. Structures and neuroprotective activities of triterpenoids from Cynomorium coccineum subsp. songaricum (Rupr.) J. Leonard

Author:
Bo Zhang; Sheng-Li Yang; Xin Li; Qian-Ru Zhang; Meng-Yin Tian; Xiao-Liang Wang; Su-Juan Wang
Source:
Phytochemistry 2022 v.198 pp. 113155
ISSN:
0031-9422
Subject:
triterpenoids,   etc   ; Cynomorium; cell death; functional foods; spectral analysis; structure-activity relationships; traditional medicine;     Show all 7 Subjects
Abstract:
... Cynomorium coccineum subsp. songaricum (Rupr.) J. Leonard has been widely used as a Chinese herbal remedy or a functional food for treating symptoms of aging or neurodegenerative diseases. A further investigation on the finding of active constituents led to the isolation and identification of four previously undescribed triterpenoids, together with 20 known compounds. Their structures were elucida ...
DOI:
10.1016/j.phytochem.2022.113155