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1. The science of vaccine safety: Summary of meeting at Wellcome Trust

Author:
Plotkin, Stanley A.; Offit, Paul A.; DeStefano, Frank; Larson, Heidi J.; Arora, Narendra Kumar; Zuber, Patrick L.F.; Fombonne, Eric; Sejvar, James; Lambert, Paul Henri; Hviid, Anders; Halsey, Neal; Garçon, Nathalie; Peden, Keith; Pollard, Andrew J.; Markowitz, Lauri E.; Glanz, Jason
Source:
Vaccine 2020 v.38 no.8 pp. 1869-1880
ISSN:
0264-410X
Subject:
vaccination,   etc   ; Papillomaviridae; experts; vaccines;     Show all 4 Subjects
Abstract:
... Vaccines are everywhere hugely successful but are also under attack. The reason for the latter is the perception by some people that vaccines are unsafe. However that may be, vaccine safety, life any other scientific subject, must be constantly studied. It was from this point of view that a meeting was organized at the Wellcome Trust in London in May 2019 to assess some aspects of vaccine safety a ...
DOI:
10.1016/j.vaccine.2020.01.024

2. Human papillomavirus vaccine coverage in Rwanda: A population-level analysis by birth cohort

Author:
Sayinzoga, Felix; Umulisa, M. Chantal; Sibomana, Hassan; Tenet, Vanessa; Baussano, Iacopo; Clifford, Gary M.
Source:
Vaccine 2020 v.38 no.24 pp. 4001-4005
ISSN:
0264-410X
Subject:
vaccination,   etc   ; Alphapapillomavirus; adolescents; girls; Rwanda;     Show all 5 Subjects
Abstract:
... In 2011, Rwanda became the first African nation to implement a national human papillomavirus (HPV) vaccination program, conceived to protect girls aged <15 years (i.e. born ≥1997). After an initial school-grade-targeted catch-up campaign, there was a transition to routine vaccination of 12 year-olds only. We aimed to produce population-level vaccine coverage estimates.The Rwandan Expanded Program ...
DOI:
10.1016/j.vaccine.2020.04.021
PubMed:
32336599
PubMed Central:
PMC7221340

3. Vaccine hesitancy and perceived behavioral control: A meta-analysis

Author:
Xiao, Xizhu; Wong, Rachel Min
Source:
Vaccine 2020
ISSN:
0264-410X
Subject:
vaccination,   etc   ; databases; meta-analysis; public health; vaccines;     Show all 5 Subjects
Abstract:
... The World Health Organization recognizes that vaccine hesitancy is a top threat to the public health. To address vaccine hesitancy, much research guided by behavioral theories attempted to examine factors that contribute to vaccination intentions. The current study synthesizes the summary effects of attitude, norms and perceived behavioral control on vaccination intentions.We searched five databas ...
DOI:
10.1016/j.vaccine.2020.04.076

4. Japanese encephalitis in the Western Pacific Region: Implication from the Republic of Korea

Author:
Choe, Young June; Jee, Youngmee; Takashima, Yoshihiro; Lee, Jong-koo
Source:
Vaccine 2020 v.38 no.13 pp. 2760-2763
ISSN:
0264-410X
Subject:
vaccination,   etc   ; encephalitis; immunity; monitoring; vaccines; South Korea;     Show all 6 Subjects
Abstract:
... Japanese encephalitis (JE) is endemic in the Western Pacific Region. We aim to describe the regional status of control of JE, based on the World Health Organization (WHO) surveillance data, and to share the experience from the Republic of Korea. Substantial progress has been made in the region to date; however, epidemiologic changes have not been delineated. The vaccination coverage should be addr ...
DOI:
10.1016/j.vaccine.2020.02.061

5. Randomization inference with general interference and censoring

Author:
Loh, Wen Wei; Hudgens, Michael G.; Clemens, John D.; Ali, Mohammad; Emch, Michael E.
Source:
Biometrics 2020 v.76 no.1 pp. 235-245
ISSN:
0006-341X
Subject:
vaccination,   etc   ; biometry; biostatistics; cholera; computer software; Bangladesh;     Show all 6 Subjects
Abstract:
... Interference occurs between individuals when the treatment (or exposure) of one individual affects the outcome of another individual. Previous work on causal inference methods in the presence of interference has focused on the setting where it is a priori assumed that there is “partial interference,” in the sense that individuals can be partitioned into groups wherein there is no interference betw ...
DOI:
10.1111/biom.13125
PubMed:
31388990
PubMed Central:
PMC7004887

6. Oral cholera vaccination coverage in an acute emergency setting in Somalia, 2017

Author:
Lubogo, Mutaawe; Mohamed, Ahmed M.; Ali, Abdullahi H.; Ali, Aden H.; Popal, Ghulam R.; Kiongo, David; Bile, Khalif Mohamud; Malik, Mamunur; Abubakar, Abdinasir
Source:
Vaccine 2020 v.38 pp. A141
ISSN:
0264-410X
Subject:
vaccination,   etc   ; cholera; households; sanitation; surveys; vaccines; Somalia;     Show all 7 Subjects
Abstract:
... The first oral cholera vaccination (OCV) campaign in Somalia was implemented between March and October 2017. It was the first time the Ministry of Health had introduced and used OCV as part of the cholera prevention and control strategies. The Ministry of Health aimed to cover 1.1 million people ≥ 1 year with 2 doses of the OCV in 11 high-risk districts. Overall, 2-dose administrative OCV coverage ...
DOI:
10.1016/j.vaccine.2020.01.015

7. Updates on immunologic correlates of vaccine-induced protection

Author:
Plotkin, Stanley A.
Source:
Vaccine 2020 v.38 no.9 pp. 2250-2257
ISSN:
0264-410X
Subject:
vaccination,   etc   ; immune response; vaccine development; vaccines;     Show all 4 Subjects
Abstract:
... Correlates of protection (CoPs) are increasingly important in the development and licensure of vaccines. Although the study of CoPs was initially directed at identifying a single immune function that could explain vaccine efficacy, it has become increasingly clear that there are often multiple functions responsible for efficacy. This review is meant to supplement prior articles on the subject, ill ...
DOI:
10.1016/j.vaccine.2019.10.046

8. The echo in flu-vaccination echo chambers: Selective attention trumps social influence

Author:
Giese, Helge; Neth, Hansjörg; Moussaïd, Mehdi; Betsch, Cornelia; Gaissmaier, Wolfgang
Source:
Vaccine 2020 v.38 no.8 pp. 2070-2076
ISSN:
0264-410X
Subject:
vaccination,   etc   ; attitudes and opinions; influenza; risk; vaccines;     Show all 5 Subjects
Abstract:
... Online discussions may impact the willingness to get vaccinated. This experiment tests how groups of individuals with consistent and inconsistent attitudes towards flu vaccination attend to and convey information online, and how they alter their corresponding risk perceptions.Out of 1859 MTurkers, we pre-selected 208 people with negative and 221 people with positive attitudes towards flu vaccinati ...
DOI:
10.1016/j.vaccine.2019.11.038

9. Resilience of HPV vaccine uptake in Denmark: Decline and recovery

Author:
Hansen, Peter R.; Schmidtblaicher, Matthias; Brewer, Noel T.
Source:
Vaccine 2020 v.38 no.7 pp. 1842-1848
ISSN:
0264-410X
Subject:
vaccination,   etc   ; cohort studies; girls; vaccines; Denmark;     Show all 5 Subjects
Abstract:
... Immunization programs’ resilience to shocks is central to their success, but little empirical evidence documents resilience in action. We sought to characterize the decline of HPV vaccination in Denmark after negative media coverage and recovery during a national information campaign.We conducted a population-based retrospective cohort study of all girls born in Denmark from 1997 to 2006 (N = 328, ...
DOI:
10.1016/j.vaccine.2019.12.019

10. Strengthening vaccination frameworks: Findings of a study on the legal foundations of National Immunization Technical Advisory Groups (NITAGs)

Author:
Harmon, Shawn H.E.; Faour, David; MacDonald, Noni E.; Graham, Janice; Steffen, Christoph; Henaff, Louise; Shendale, Stephanie
Source:
Vaccine 2020 v.38 no.4 pp. 840-846
ISSN:
0264-410X
Subject:
vaccination,   etc   ; experts; laws and regulations; models; vaccines;     Show all 5 Subjects
Abstract:
... In 2017, the Strategic Advisory Group of Experts on Immunization’s Assessment Report of the Global Vaccine Action Plan noted the need to “better document the ways in which legislation and regulations have been used to promote or undermine immunization at the national level”. Despite National Immunization Technical Advisory Groups (NITAGs) now existing in over 134 countries worldwide, there has bee ...
DOI:
10.1016/j.vaccine.2019.10.085

11. Seeking the optimal schedule for chickenpox vaccination in Canada: Using an agent-based model to explore the impact of dose timing, coverage and waning of immunity on disease outcomes

Author:
Rafferty, Ellen R.S.; McDonald, Wade; Osgood, Nathaniel D.; Qian, Weicheng; Doroshenko, Alexander
Source:
Vaccine 2020 v.38 no.3 pp. 521-529
ISSN:
0264-410X
Subject:
vaccination,   etc   ; antigens; immunity; models; risk; vaccines; Alberta;     Show all 7 Subjects
Abstract:
... Many countries continue to consider implementing a universal chickenpox vaccine program; however, there is no consensus on the most appropriate and effective timing between vaccine doses. The chickenpox vaccine schedule debate is highlighted in Canada, where there are currently eight different vaccine schedules across the country. The objective of this study was to test the overall effectiveness o ...
DOI:
10.1016/j.vaccine.2019.10.065

12. Vaccination-associated acute disseminated encephalomyelitis

Author:
Torisu, Hiroyuki; Okada, Kenji
Source:
Vaccine 2019 v.37 no.8 pp. 1126-1129
ISSN:
0264-410X
Subject:
vaccination,   etc   ; encephalitis; vaccines;     Show all 3 Subjects
Abstract:
... While the basic definition of vaccination-associated acute disseminated encephalomyelitis (ADEM) is relatively clear and easily understandable, it is often difficult to diagnose ADEM based on clinical findings alone. ADEM is actually a heterogeneous clinical syndrome that can be approximately characterized by encephalomyelitis with multiple inflammatory demyelination, autoimmune causes, and relati ...
DOI:
10.1016/j.vaccine.2019.01.021

13. Lessons on causality assessment and communications from the 2019 South-East Asia Regional (SEAR) workshop on inter-country expert review of selected Adverse Events Following Immunization (AEFI) cases

Author:
MacDonald, Noni E.; Guichard, Stephane; Arora, Narendra; Menning, Lisa; Wilhelm, Elisabeth
Source:
Vaccine 2020 v.38 no.32 pp. 4924-4932
ISSN:
0264-410X
Subject:
vaccination,   etc   ; experts; monitoring; planning; vaccines; South East Asia;     Show all 6 Subjects
Abstract:
... Surveillance of AEFI is fundamental for improving safety and maintaining public support for vaccination. In SEAR, billions of doses of vaccine are given annually. The objective of the 2019 SEAR AEFI training workshop was to further strengthen in-country vaccine safety, assess capacity compared to 2014 and to better integrate communication into the AEFI causality assessment program.A 3 ½ day worksh ...
DOI:
10.1016/j.vaccine.2019.09.109

14. Are vaccinated measles cases protected against severe disease?

Author:
Bonneton, M.; Antona, D.; Danis, K.; Aït-Belghiti, F.; Levy-Bruhl, D.
Source:
Vaccine 2020 v.38 no.29 pp. 4516-4519
ISSN:
0264-410X
Subject:
vaccination,   etc   ; compliance; disease severity; measles; relative risk; vaccines; France;     Show all 7 Subjects
Abstract:
... We aimed to estimate vaccine effectiveness against severe measles based on the number of vaccine doses administered and the time since last vaccination.We included measles cases aged at least 2 years and born since 1980 who were notified in France between 2006 and mid-2019. We considered two severity levels (moderate, severe) and calculated adjusted relative risks (aRR) using multinomial logistic ...
DOI:
10.1016/j.vaccine.2020.05.005

15. From bad to worse: The representation of the HPV vaccine Facebook

Author:
Luisi, Monique L.R.
Source:
Vaccine 2020 v.38 no.29 pp. 4564-4573
ISSN:
0264-410X
Subject:
vaccination,   etc   ; health beliefs; models; social networks; stakeholders; vaccines;     Show all 6 Subjects
Abstract:
... Anti-HPV vaccination social media messages may increase vaccine hesitancy and avoidance. This study analyzed (1) the first decade of public, HPV-vaccine related Facebook posts’ characteristics, engagement, and health belief messages; (2) relationships between variables; (3) how those variables changed over time; and (4) identified and analyzed the posts with the most engagement.The data sample con ...
DOI:
10.1016/j.vaccine.2020.05.016

16. Immunogenicity and safety of a quadrivalent inactivated influenza vaccine in healthy subjects aged 3 to 17 years old: A phase III, open label, single-arm study

Author:
Chang, Chia-Yuan; Cho, Ching-Yi; Lai, Chou-Cheng; Lu, Chun-Yi; Chang, Luan-Yin; Hung, Miao-Chiu; Huang, Li-Min; Wu, Keh-Gong
Source:
Vaccine 2020 v.38 no.22 pp. 3839-3846
ISSN:
0264-410X
Subject:
vaccination,   etc   ; children; hemagglutination; humans; immunogenicity; influenza; influenza vaccines; seroconversion; Taiwan;     Show all 9 Subjects
Abstract:
... Quadrivalent influenza vaccines are particularly valuable during seasons in which a mismatch occurs between the predicted influenza B lineage for the trivalent influenza vaccine and the circulating strain. This study evaluated the immunogenicity and safety of a quadrivalent inactivated influenza vaccine AdimFlu-S manufactured in Taiwan for the 2016–2017 influenza season in healthy children.A total ...
DOI:
10.1016/j.vaccine.2020.03.048

17. Use of tetanus-diphtheria (Td) vaccine in children 4–7 years of age: World Health Organization consultation of experts

Author:
Desai, Shalini; Scobie, Heather M.; Cherian, Thomas; Goodman, Tracey
Source:
Vaccine 2020 v.38 no.21 pp. 3800-3807
ISSN:
0264-410X
Subject:
vaccination,   etc   ; children; diphtheria; experts; immune response; models; tetanus; vaccines;     Show all 8 Subjects
Abstract:
... For lifetime protection against diphtheria and tetanus, the World Health Organization (WHO) recommends six doses of diphtheria and tetanus containing vaccines. Td (reduced diphtheria toxoid, ≥2–5 IU) vaccines are currently licensed for ages 7 years and older, but use of Td vaccine for ages 4 years and older would have advantages for immunization programs in many low- and middle-income countries. F ...
DOI:
10.1016/j.vaccine.2020.01.018

18. Impact of a 2-dose voluntary vaccination strategy on varicella epidemiology in Beijing, 2011–2017

Author:
Suo, Luodan; Lu, Li; Zhao, Dan; Pang, Xinghuo
Source:
Vaccine 2020 v.38 no.20 pp. 3690-3696
ISSN:
0264-410X
Subject:
vaccination,   etc   ; adolescents; adults; children; epidemiology; monitoring; screening; vaccines; China;     Show all 9 Subjects
Abstract:
... One-dose voluntary varicella vaccination for children was introduced in Beijing since 1998. In Oct 2012, a second dose varicella vaccine (VarV) was recommended to further decrease varicella disease and the outbreaks. We describe the impact of the 2-dose voluntary vaccination strategy on varicella epidemiology in Beijing, China.Varicella incidence rates and outbreak characteristics in 2011–2017 was ...
DOI:
10.1016/j.vaccine.2020.01.087

19. Normal human lymph node T follicular helper cells and germinal center B cells accessed via fine needle aspirations

Author:
Havenar-Daughton, Colin; Newton, Isabel G.; Zare, Somaye Y.; Reiss, Samantha M.; Schwan, Brittany; Suh, Min Ji; Hasteh, Farnaz; Levi, Gina; Crotty, Shane
Source:
Journal of immunological methods 2020 v.479 pp. 112746
ISSN:
0022-1759
Subject:
vaccination,   etc   ; B-lymphocytes; autoimmune diseases; humans; hypersensitivity; lymph nodes; pathogens;     Show all 7 Subjects
Abstract:
... Germinal centers (GC) are critically important for maturation of the antibody response and generation of memory B cells, processes that form the basis for long-term protection from pathogens. GCs only occur in lymphoid tissue, such as lymph nodes, and are not present in blood. Therefore, GC B cells and GC T follicular helper (TFH) cells are not well-studied in humans under normal healthy condition ...
DOI:
10.1016/j.jim.2020.112746
PubMed:
31958451
PubMed Central:
PMC7200018

20. School-based vaccination programmes: An evaluation of school immunisation delivery models in England in 2015/16

Author:
Tiley, K.; Tessier, E.; White, J.M.; Andrews, N.; Saliba, V.; Ramsay, M.; Edelstein, M.
Source:
Vaccine 2020 v.38 no.15 pp. 3149-3156
ISSN:
0264-410X
Subject:
vaccination,   etc   ; Papillomaviridae; adolescents; diphtheria; models; schools; tetanus; vaccines; England;     Show all 9 Subjects
Abstract:
... Schools are increasingly being used to deliver vaccines. In 2015/16 three school-based vaccination programmes were delivered to adolescents in England: human papillomavirus (HPV), meningococcal groups A, C, W and Y disease (MenACWY) and tetanus, diphtheria and polio (Td/IPV). We assessed how school delivery models impact vaccine coverage and how a delivery model for one programme may impact anothe ...
DOI:
10.1016/j.vaccine.2020.01.031