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1. Updates on immunologic correlates of vaccine-induced protection

Author:
Plotkin, Stanley A.
Source:
Vaccine 2020 v.38 no.9 pp. 2250-2257
ISSN:
0264-410X
Subject:
vaccine development; vaccines,   etc   ; immune response; vaccination;     Show all 4 Subjects
Abstract:
... Correlates of protection (CoPs) are increasingly important in the development and licensure of vaccines. Although the study of CoPs was initially directed at identifying a single immune function that could explain vaccine efficacy, it has become increasingly clear that there are often multiple functions responsible for efficacy. This review is meant to supplement prior articles on the subject, ill ...
DOI:
10.1016/j.vaccine.2019.10.046

2. Global vaccine action plan lessons learned I: Recommendations for the next decade

Author:
MacDonald, Noni; Mohsni, Ezzeddine; Al-Mazrou, Yagob; Kim Andrus, Jon; Arora, Narendra; Elden, Susan; Madrid, Marie-Yvette; Martin, Rebecca; Mahmoud Mustafa, Amani; Rees, Helen; Salisbury, David; Zhao, Qinjian; Jones, Ian; Steffen, Christoph A.; Hombach, Joachim; O'Brien, Katherine L.; Cravioto, Alejandro
Source:
Vaccine 2020 v.38 no.33 pp. 5364-5371
ISSN:
0264-410X
Subject:
vaccines,   etc   ; experts; immunization; monitoring;     Show all 4 Subjects
Abstract:
... The Global Vaccine Action Plan 2011–2020 (GVAP) was developed to realize the ambitions of the Decade of Vaccines – that all individuals and communities enjoy lives free from vaccine-preventable diseases. It included a comprehensive monitoring and evaluation/accountability framework to assess progress towards global targets with recommendations for corrective actions. While many of the GVAP targets ...
DOI:
10.1016/j.vaccine.2020.05.003

3. The science of vaccine safety: Summary of meeting at Wellcome Trust

Author:
Plotkin, Stanley A.; Offit, Paul A.; DeStefano, Frank; Larson, Heidi J.; Arora, Narendra Kumar; Zuber, Patrick L.F.; Fombonne, Eric; Sejvar, James; Lambert, Paul Henri; Hviid, Anders; Halsey, Neal; Garçon, Nathalie; Peden, Keith; Pollard, Andrew J.; Markowitz, Lauri E.; Glanz, Jason
Source:
Vaccine 2020 v.38 no.8 pp. 1869-1880
ISSN:
0264-410X
Subject:
vaccines,   etc   ; Papillomaviridae; experts; vaccination;     Show all 4 Subjects
Abstract:
... Vaccines are everywhere hugely successful but are also under attack. The reason for the latter is the perception by some people that vaccines are unsafe. However that may be, vaccine safety, life any other scientific subject, must be constantly studied. It was from this point of view that a meeting was organized at the Wellcome Trust in London in May 2019 to assess some aspects of vaccine safety a ...
DOI:
10.1016/j.vaccine.2020.01.024

4. Renewing the Fight Against TB with an Old Vaccine

Author:
Scriba, Thomas J.; Mizrahi, Valerie
Source:
Cell 2020 v.180 no.5 pp. 829-831
ISSN:
0092-8674
Subject:
vaccine development; vaccines,   etc   ; Primates; intravenous injection; tuberculosis; vaccination;     Show all 6 Subjects
Abstract:
... Prevention of pulmonary tuberculosis by vaccination has proven an elusive goal. In a recent study, Darrah et al. show that prevention of infection and disease can be achieved in non-human primates by intravenous administration of the century-old vaccine BCG. This finding heralds a step-change in the approach to TB vaccine development. ...
DOI:
10.1016/j.cell.2020.02.024

5. Global harmonization of vaccine testing requirements: Making elimination of the ATT and TABST a concrete global achievement

Author:
Viviani, Laura; Halder, Marlies; Gruber, Marion; Bruckner, Lukas; Cussler, Klaus; Sanyal, Gautam; Srinivas, Geetha; Goel, Sunil; Kaashoek, Marianne; Litthauer, Derek; Lopes da Silva, Arthur Leonardo; Sakanyan, Elena; Aprea, Patricia; Jin, Hongtao; Vandeputte, Joris; Seidle, Troy; Yakunin, Dimitriy
Source:
Biologicals 2020 v.63 pp. 101-105
ISSN:
1045-1056
Subject:
vaccine development; vaccines,   etc   ; experts; humans; laboratory animals; toxicity testing; China;     Show all 7 Subjects
Abstract:
... This one-day symposium organized by Humane Society International (HSI) brought together 18 international experts from Argentina, Brazil, China, Europe, India, Russia, South Africa and the United States to discuss the elimination of the abnormal toxicity test (ATT) from the testing requirements for human vaccines as well as the target animal batch safety test (TABST) and the laboratory animal batch ...
DOI:
10.1016/j.biologicals.2019.10.007

6. Immunization stress-related response – Redefining immunization anxiety-related reaction as an adverse event following immunization

Author:
Gold, Michael S.; MacDonald, Noni E.; McMurtry, C. Meghan; Balakrishnan, Madhava Ram; Heininger, Ulrich; Menning, Lisa; Benes, Oleg; Pless, Robert; Zuber, Patrick L.F.
Source:
Vaccine 2020 v.38 no.14 pp. 3015-3020
ISSN:
0264-410X
Subject:
vaccines,   etc   ; immunization; medical sciences; terminology;     Show all 4 Subjects
Abstract:
... The Council for the International Organizations of Medical Sciences (CIOMS) and WHO working group on pharmacovigilance defines five cause specific AEFI which includes an immunization anxiety-related reaction. Historically this term has been used to describe a range of symptoms and signs that may arise after immunization that are related to “anxiety” about the immunization. However, the term “anxie ...
DOI:
10.1016/j.vaccine.2020.02.046

7. Biomimic strategies for modulating the interaction between particle adjuvants and antigen-presenting cells

Author:
Wu, Jie; Ma, Guanghui
Source:
Biomaterials science 2020 v.8 no.9 pp. 2366-2375
ISSN:
2047-4849
Subject:
vaccine adjuvants; vaccine development; vaccines,   etc   ; antigen-presenting cells; antigens; biomimetics; immune response; pathogens; physicochemical properties;     Show all 9 Subjects
Abstract:
... Developing effective adjuvants is becoming increasingly important for the research of vaccine formulations. The addition of adjuvants could enhance the immune response, reduce the antigen dosage and prolong the protection time. In recent years, biomimetic strategies have been adopted in the design of vaccine adjuvants to achieve better immune protection efficiency. Particularly those particle adju ...
DOI:
10.1039/c9bm02098e

8. Imitation of nature: Bionic design in the study of particle adjuvants

Author:
Wu, Jie; Ma, Guanghui
Source:
Journal of controlled release 2019 v.303 pp. 101-108
ISSN:
0168-3659
Subject:
vaccine adjuvants; vaccine development; vaccines,   etc   ; pathogens;     Show all 4 Subject
Abstract:
... Vaccine adjuvants play an increasingly important role in the development of modern vaccines. Among of them, particle adjuvants have received wide attention due to their unique properties. In order to develop effective particle adjuvants, mimicking natural pathogens is one of the important strategies. By adopting different materials, preparation methods and design ideas, the researchers obtained va ...
DOI:
10.1016/j.jconrel.2019.04.004

9. Review of pediatric encephalitis and encephalopathy cases following immunization reported to the Canadian Immunization Monitoring Program Active (IMPACT) from 1992 to 2012

Author:
Tam, Jennifer; Tran, Dat; Bettinger, Julie A.; Moore, Dorothy; Sauvé, Laura; Jadavji, Taj; Tan, Ben; Vaudry, Wendy; Halperin, Scott A.; Top, Karina A.
Source:
Vaccine 2020 v.38 no.28 pp. 4457-4463
ISSN:
0264-410X
Subject:
inactivated vaccines; influenza vaccines; live vaccines,   etc   ; consciousness; encephalitis; encephalopathy; etiology; influenza; measles; monitoring; patients; seizures; tetanus; vaccination;     Show all 14 Subjects
Abstract:
... Neurological adverse events following immunization (AEFI) remain poorly characterized. Our objective was to describe pediatric acute and chronic encephalopathy and encephalitis cases following immunization reported via active sentinel surveillance from 1992 to 2012.This case series provides a descriptive analysis of encephalopathy/encephalitis admissions reported to the Canadian Immunization Monit ...
DOI:
10.1016/j.vaccine.2020.04.035

10. A DIVA vaccine strain lacking RpoS and the secondary messenger c-di-GMP for protection against salmonellosis in pigs

Author:
Gil, Carmen; Latasa, Cristina; García-Ona, Enrique; Lázaro, Isidro; Labairu, Javier; Echeverz, Maite; Burgui, Saioa; García, Begoña; Lasa, Iñigo; Solano, Cristina
Source:
Veterinary research 2020 v.51 no.1 pp. 3
ISSN:
1297-9716
Subject:
vaccines,   etc   ; immunologic techniques; salmonellosis; second messengers; swine;     Show all 5 Subjects
Abstract:
... Salmonellosis is the second most common food-borne zoonosis in the European Union, with pigs being a major reservoir of this pathogen. Salmonella control in pig production requires multiple measures amongst which vaccination may be used to reduce subclinical carriage and shedding of prevalent serovars, such as Salmonella enterica serovar Typhimurium. Live attenuated vaccine strains offer advantage ...
DOI:
10.1186/s13567-019-0730-3
PubMed:
31924274
PubMed Central:
PMC6954585

11. Vaccine hesitancy and perceived behavioral control: A meta-analysis

Author:
Xiao, Xizhu; Wong, Rachel Min
Source:
Vaccine 2020 v.38 no.33 pp. 5131-5138
ISSN:
0264-410X
Subject:
vaccines,   etc   ; databases; meta-analysis; public health; vaccination;     Show all 5 Subjects
Abstract:
... The World Health Organization recognizes that vaccine hesitancy is a top threat to the public health. To address vaccine hesitancy, much research guided by behavioral theories attempted to examine factors that contribute to vaccination intentions. The current study synthesizes the summary effects of attitude, norms and perceived behavioral control on vaccination intentions.We searched five databas ...
DOI:
10.1016/j.vaccine.2020.04.076

12. Assessment of the long-term efficacy of a dengue vaccine against symptomatic, virologically-confirmed dengue disease by baseline dengue serostatus

Author:
Dayan, Gustavo H.; Langevin, Edith; Gilbert, Peter B.; Wu, Yukun; Moodie, Zoe; Forrat, Rémi; Price, Brenda; Frago, Carina; Bouckenooghe, Alain; Cortes, Margarita; Noriega, Fernando; DiazGranados, Carlos A.
Source:
Vaccine 2020 v.38 no.19 pp. 3531-3536
ISSN:
0264-410X
Subject:
vaccines,   etc   ; dengue; monitoring; seroprevalence; Latin America;     Show all 5 Subjects
Abstract:
... CYD-TDV is a live, attenuated, tetravalent dengue vaccine licensed in 21 countries. We undertook a post-hoc analysis of the long-term efficacy of CYD-TDV during the surveillance expansion phase (SEP) of two Phase III studies (CYD14 in the Asia-Pacific region; CYD15 in Latin America). The SEP included approximately Year 5 and the entire Year 6 of follow-up after the first study injection. Vaccine e ...
DOI:
10.1016/j.vaccine.2020.03.029

13. A Vaccine against Ebola Virus

Author:
Ollmann Saphire, Erica
Source:
Cell 2020 v.181 no.1 pp. 6
ISSN:
0092-8674
Subject:
vaccines,   etc   ; Ebolavirus; humans; public health; Canada;     Show all 5 Subjects
Abstract:
... Ervebo is the first licensed vaccine for prevention of Ebola virus disease. The vaccine, originally developed by the Public Health Agency of Canada, is delivered in a single 1 mL dose and has been delivered to >200,000 people in an ongoing 2018–2020 outbreak of disease. To view this Bench to Bedside, open or download the PDF. ...
DOI:
10.1016/j.cell.2020.03.011

14. Japanese encephalitis in the Western Pacific Region: Implication from the Republic of Korea

Author:
Choe, Young June; Jee, Youngmee; Takashima, Yoshihiro; Lee, Jong-koo
Source:
Vaccine 2020 v.38 no.13 pp. 2760-2763
ISSN:
0264-410X
Subject:
vaccines,   etc   ; encephalitis; immunity; monitoring; vaccination; South Korea;     Show all 6 Subjects
Abstract:
... Japanese encephalitis (JE) is endemic in the Western Pacific Region. We aim to describe the regional status of control of JE, based on the World Health Organization (WHO) surveillance data, and to share the experience from the Republic of Korea. Substantial progress has been made in the region to date; however, epidemiologic changes have not been delineated. The vaccination coverage should be addr ...
DOI:
10.1016/j.vaccine.2020.02.061

15. Oral cholera vaccination coverage in an acute emergency setting in Somalia, 2017

Author:
Lubogo, Mutaawe; Mohamed, Ahmed M.; Ali, Abdullahi H.; Ali, Aden H.; Popal, Ghulam R.; Kiongo, David; Bile, Khalif Mohamud; Malik, Mamunur; Abubakar, Abdinasir
Source:
Vaccine 2020 v.38 pp. A141
ISSN:
0264-410X
Subject:
vaccines,   etc   ; cholera; households; sanitation; surveys; vaccination; Somalia;     Show all 7 Subjects
Abstract:
... The first oral cholera vaccination (OCV) campaign in Somalia was implemented between March and October 2017. It was the first time the Ministry of Health had introduced and used OCV as part of the cholera prevention and control strategies. The Ministry of Health aimed to cover 1.1 million people ≥ 1 year with 2 doses of the OCV in 11 high-risk districts. Overall, 2-dose administrative OCV coverage ...
DOI:
10.1016/j.vaccine.2020.01.015

16. Social mobilization for cholera prevention & control in India: Building on the existing framework

Author:
Gupta, Sanjukta Sen; Gupta, Satish Kumar
Source:
Vaccine 2020 v.38 pp. A181
ISSN:
0264-410X
Subject:
vaccines,   etc   ; cholera; disasters; guidelines; immunization; Haiti; India;     Show all 7 Subjects
Abstract:
... Social mobilization is an important component of the delivery of vaccines and has to be carried out at different levels. It plays a very critical role in success of a campaign, as was shown by the Polio eradication program in India that was supported by SMNet, a platform created for the purpose. Learnings from this has been used for other vaccine deployments in India as well. In addition, there is ...
DOI:
10.1016/j.vaccine.2019.07.047

17. The echo in flu-vaccination echo chambers: Selective attention trumps social influence

Author:
Giese, Helge; Neth, Hansjörg; Moussaïd, Mehdi; Betsch, Cornelia; Gaissmaier, Wolfgang
Source:
Vaccine 2020 v.38 no.8 pp. 2070-2076
ISSN:
0264-410X
Subject:
vaccines,   etc   ; attitudes and opinions; influenza; risk; vaccination;     Show all 5 Subjects
Abstract:
... Online discussions may impact the willingness to get vaccinated. This experiment tests how groups of individuals with consistent and inconsistent attitudes towards flu vaccination attend to and convey information online, and how they alter their corresponding risk perceptions.Out of 1859 MTurkers, we pre-selected 208 people with negative and 221 people with positive attitudes towards flu vaccinati ...
DOI:
10.1016/j.vaccine.2019.11.038

18. Resilience of HPV vaccine uptake in Denmark: Decline and recovery

Author:
Hansen, Peter R.; Schmidtblaicher, Matthias; Brewer, Noel T.
Source:
Vaccine 2020 v.38 no.7 pp. 1842-1848
ISSN:
0264-410X
Subject:
vaccines,   etc   ; cohort studies; girls; vaccination; Denmark;     Show all 5 Subjects
Abstract:
... Immunization programs’ resilience to shocks is central to their success, but little empirical evidence documents resilience in action. We sought to characterize the decline of HPV vaccination in Denmark after negative media coverage and recovery during a national information campaign.We conducted a population-based retrospective cohort study of all girls born in Denmark from 1997 to 2006 (N = 328, ...
DOI:
10.1016/j.vaccine.2019.12.019

19. Pertussis vaccines: The first hundred years

Author:
Guiso, Nicole; Meade, Bruce D.; Wirsing von König, Carl Heinz
Source:
Vaccine 2020 v.38 no.5 pp. 1271-1276
ISSN:
0264-410X
Subject:
vaccines,   etc   ; children; immunity; infants; morbidity; mortality;     Show all 6 Subjects
Abstract:
... Vaccines against pertussis have been used for more than a hundred years. This review describes the development of whole-cell (wP) and acellular pertussis (aP) vaccines, which, as DTP combination vaccines, have significantly reduced morbidity and mortality from pertussis, and which currently serve as the building blocks for a variety of vaccines used to immunize all infants worldwide. Two series of ...
DOI:
10.1016/j.vaccine.2019.11.022

20. Strengthening vaccination frameworks: Findings of a study on the legal foundations of National Immunization Technical Advisory Groups (NITAGs)

Author:
Harmon, Shawn H.E.; Faour, David; MacDonald, Noni E.; Graham, Janice; Steffen, Christoph; Henaff, Louise; Shendale, Stephanie
Source:
Vaccine 2020 v.38 no.4 pp. 840-846
ISSN:
0264-410X
Subject:
vaccines,   etc   ; experts; laws and regulations; models; vaccination;     Show all 5 Subjects
Abstract:
... In 2017, the Strategic Advisory Group of Experts on Immunization’s Assessment Report of the Global Vaccine Action Plan noted the need to “better document the ways in which legislation and regulations have been used to promote or undermine immunization at the national level”. Despite National Immunization Technical Advisory Groups (NITAGs) now existing in over 134 countries worldwide, there has bee ...
DOI:
10.1016/j.vaccine.2019.10.085