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1. Special Issue “Viral Shedding and Transmission in Zoonotic Diseases”

Author:
Kateri Bertran; Martí Cortey; Miriã F. Criado
Source:
Viruses 2022 v.14 no.6 pp. -
ISSN:
1999-4915
Subject:
viral shedding,   etc   ; hosts; infectious diseases; virus transmission; viruses; zoonoses;     Show all 6 Subjects
Abstract:
... The papers published in this Special Issue represent only a glimpse of the vast diversity of viral infectious diseases, and the complexity of their interactions with the host, that have an impact on human and animal health [...] ...
DOI:
10.3390/v14061190

2. Retraction notice to “Mycoplasma synoviae vaccine modifies virus shedding and immune responses of avian influenza (H9N2) infection in commercial layers” [Poult. Sci. 96 (2017) 3086–3095]

Author:
Sajid Umar; Muhammad Tanweer; Mudassar Iqbal; Asad Shahzad; Farooq Hassan; Muhammad Usman; Fozia Sarwar; Hajra Qadir; Sajjad Asif; un-Nisa Qamar; Muhammad Younus; Asif Ali; Mehboob Akbar; Farhan Towakal; Muhammad Ali Shah
Source:
Poultry science 2020 v.99 no.8 pp. R4102
ISSN:
0032-5791
Subject:
viral shedding,   etc   ; Mycoplasma synoviae; avian influenza; immune response; issues and policy; poults; vaccines;     Show all 7 Subjects
Abstract:
... This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).The authors retract the above paper due to: 1) conflict of interest among the authors; and 2) addition of co-author Dr. Muhammad Younus without his knowledge or permission. The authors apologize for these two grave mistakes. ...
DOI:
10.1016/j.psj.2020.07.002

3. Infection dynamics and shedding kinetics of nervous necrosis virus in juvenile seven band grouper using an intraperitoneal infection-cohabitation model

Author:
Rahul Krishnan; Syed Shariq Nazir Qadiri; Jae-Ok Kim; Myung-Joo Oh
Source:
Aquaculture 2021 v.530 pp. 735957
ISSN:
0044-8486
Subject:
viral shedding,   etc   ; Betanodavirus; Hyporthodus septemfasciatus; decision making; farmed fish; fish diseases; grouper; juveniles; models; mortality; viral load;     Show all 11 Subjects
Abstract:
... Nervous necrosis virus (NNV) affects more than 177 species of cultured fish including seven band grouper. The present study evaluated the shedding and transmission kinetics of NNV in seven band groupers using a cohabitation challenge model. Initial infection studied by intraperitoneal (IP) injection showed shedding of NNV was acute and peaked within 3–5 days after exposure. This was followed by a ...
DOI:
10.1016/j.aquaculture.2020.735957

4. Field-based method for assessing duration of infectivity for influenza A viruses in the environment

Author:
Andrew B. Reeves; Andrew M. Ramey; Joshua C. Koch; Rebecca L. Poulson; David E. Stallknecht
Source:
Journal of virological methods 2020 v.277 pp. 113818
ISSN:
0166-0934
Subject:
viral shedding,   etc   ; Influenza A virus; autumn; feces; pH; pathogen survival; pathogenicity; ponds; water temperature; waterfowl; wetlands; winter; Alaska;     Show all 13 Subjects
Abstract:
... Understanding influenza A virus (IAV) persistence in wetlands is limited by a paucity of field studies relating to the maintenance of infectivity over time. The duration of IAV infectivity in water has been assessed under variable laboratory conditions, but results are difficult to translate to more complex field conditions. We tested a field-based method to assess the viability of IAVs in an Alas ...
DOI:
10.1016/j.jviromet.2020.113818

5. A class Ⅰ lentogenic newcastle disease virus strain confers effective protection against the prevalent strains

Author:
Shu-yun Li; Guo-jin You; Ji-teng Du; Jing Xia; Yi-ping Wen; Xiao-bo Huang; Qing Zhao; Xin-feng Han; Qi-gui Yan; Rui Wu; San-jie Cao; Yong Huang
Source:
Biologicals 2020 v.63 pp. 74-80
ISSN:
1045-1056
Subject:
viral shedding,   etc   ; Avian orthoavulavirus 1; antiserum; chickens; genotype; humoral immunity; serotypes; signs and symptoms (animals and humans); vaccines;     Show all 9 Subjects
Abstract:
... The traditional vaccine strains, such as LaSota, do not completely prevent the shedding of NDV. An ideal vaccine which could not only prevent the clinical signs, but significantly reduce the shedding of NDV is urgently needed for the eradication of ND. In this study, an NDV isolate APMV-1/Chicken/China (SC)/PT3/2016 (hereafter referred as PT3) was identified as a class Ⅰ NDV and a lentogenic strai ...
DOI:
10.1016/j.biologicals.2019.11.001

6. Conserved HA-peptides expressed along with flagellin in Trichoplusia ni larvae protects chicken against intranasal H7N1 HPAIV challenge

Author:
Marta Sisteré-Oró; Susana Martínez-Pulgarín; David Solanes; Veljko Veljkovic; Sergi López-Serrano; Lorena Córdoba; Ivan Cordón; José M. Escribano; Ayub Darji
Source:
Vaccine 2020 v.38 no.3 pp. 416-422
ISSN:
0264-410X
Subject:
viral shedding,   etc   ; Baculoviridae; Orthomyxoviridae; Trichoplusia ni; chickens; epitopes; flagellin; immune response; immunization; signs and symptoms (animals and humans); vaccines; zoonoses;     Show all 12 Subjects
Abstract:
... The immunization of poultry where H5 and H7 influenza viruses (IVs) are endemic is one of the strategies to prevent unexpected zoonoses. Our group has been focused on conserved HA-epitopes as potential vaccine candidates to obtain multivalent immune responses against distinct IV subtypes. In this study, two conserved epitopes (NG-34 and CS-17) fused to flagellin were produced in a Baculovirus plat ...
DOI:
10.1016/j.vaccine.2019.11.006

7. Genetic and antigenic heterogeneity of GI-1/Massachusetts lineage infectious bronchitis virus variants recently isolated in China

Author:
Jie Sheng; Mengting Ren; Zongxi Han; Junfeng Sun; Yan Zhao; Shengwang Liu
Source:
Poultry science 2020 v.99 no.11 pp. 5440-5451
ISSN:
0032-5791
Subject:
viral shedding,   etc   ; Infectious bronchitis virus; amino acids; chickens; evolution; flocks; genome; live vaccines; mutation; neutralization tests; pathogenicity; reverse genetics; China;     Show all 13 Subjects
Abstract:
... Four GI-1/Massachusetts-type (GI-1/Mass-type) infectious bronchitis virus (IBV) strains were isolated and the complete genomes of these isolates, coupled with the Mass-type live-attenuated vaccine H120 and the Mass-type pathogenic M41 strains, were sequenced in the present study. Our results show that isolates LJL/140820 and I0306/17 may be derived from the Ma5 (another Mass-type live-attenuated v ...
DOI:
10.1016/j.psj.2020.08.037

8. Phylogenetic analysis of infectious bronchitis virus circulating in southern China in 2016–2017 and evaluation of an attenuated strain as a vaccine candidate

Author:
Libin Chen; Bin Xiang; Yanfen Hong; Qian Li; Haoyun Du; Qiuyan Lin; Ming Liao; Tao Ren; Chenggang Xu
Source:
Archives of virology 2021 v.166 no.1 pp. 73-81
ISSN:
0304-8608
Subject:
viral shedding,   etc   ; Infectious bronchitis virus; chicken eggs; chickens; farms; genotype; infection; infectious bronchitis; live vaccines; phylogeny; poultry industry; protective effect; respiratory tract diseases; safety testing; signs and symptoms (animals and humans); specific pathogen-free animals; strains; virology; China;     Show all 19 Subjects
Abstract:
... Avian infectious bronchitis (IB) is a highly contagious viral respiratory disease, caused by infectious bronchitis virus (IBV), that poses an important economic threat to the poultry industry. In recent years, genotypes GI-7, GI-13, and GI-19 have been the most prevalent IBV strains in China. However, in this study, we found that most IBV strains from southern China in 2016–2017 belonged to genoty ...
DOI:
10.1007/s00705-020-04851-9

9. Pediatric Enteroviral Central Nervous System Infections in Bialystok, Poland: Epidemiology, Viral Types, and Drivers of Seasonal Variation

Author:
Kacper Toczylowski; Magdalena Wieczorek; Ewa Bojkiewicz; Magdalena Wietlicka-Piszcz; Beata Gad; Artur Sulik
Source:
Viruses 2020 v.12 no.8 pp. -
ISSN:
1999-4915
Subject:
viral shedding,   etc   ; Enterovirus; air temperature; autumn; central nervous system; children; epidemiology; monitoring; mutation rate; phylogeny; seasonal variation; summer; temperate zones; vaccines; Poland;     Show all 15 Subjects
Abstract:
... Enteroviruses are common causes of infections of the central nervous system (CNS) that in temperate climates tend to peak in the summer. The aim of the study was to describe epidemiology, drivers of seasonality, and types of enteroviruses causing infections of the CNS in children in Northeastern Poland. We prospectively collected data on children hospitalized with infection of the CNS attributed t ...
DOI:
10.3390/v12080893

10. Improved foot-and-mouth disease vaccine with O PanAsia-2 strain protect pigs against O/Jincheon/SKR/2014 originated from South Korea

Author:
Mi-Kyeong Ko; Hye-Eun Jo; Joo-Hyung Choi; Su-Hwa You; Sung Ho Shin; Hyundong Jo; Min Ja Lee; Su-Mi Kim; Byounghan Kim; Jong-Hyeon Park
Source:
Vaccine 2020 v.38 no.5 pp. 1120-1128
ISSN:
0264-410X
Subject:
viral shedding,   etc   ; antibody formation; cattle; foot-and-mouth disease; neutralization; neutralizing antibodies; swine; swine diseases; vaccination; vaccine development; vaccines; viruses; South Korea;     Show all 13 Subjects
Abstract:
... Efforts are required to develop foot-and-mouth disease (FMD) vaccines in Asia that can respond to the type O outbreaks that have continued with the devastating damage since 2010. It is necessary to develop vaccine strains that can provide protection against the ME-SA topotype, which has tended to spread into neighboring areas, and the frequent SEA topotype outbreaks. To this end, this study aimed ...
DOI:
10.1016/j.vaccine.2019.11.029

11. Novel goose-origin astrovirus infection in geese: the effect of age at infection

Author:
Da An; Ji Zhang; Jing Yang; Yi Tang; Youxiang Diao
Source:
Poultry science 2020 v.99 no.9 pp. 4323-4333
ISSN:
0032-5791
Subject:
viral shedding,   etc   ; RNA; cytokines; death; goslings; gout; histopathology; infectious diseases; kidneys; liver; pathogens; poultry diseases; signs and symptoms (animals and humans); China;     Show all 14 Subjects
Abstract:
... Since 2017, a serious infectious disease characterized by visceral gout has emerged in China's main goose-producing regions. The disease has caused huge economic losses to China's goose industry. In our previous study, we determined that the pathogen causing gout in goslings is a novel goose-origin astrovirus, designated as AStV/SDPY/Goose/1116/17 (AStV-SDPY) strain. To investigate the effect of h ...
DOI:
10.1016/j.psj.2020.05.041

12. Fecal viral shedding in COVID-19 patients: Clinical significance, viral load dynamics and survival analysis

Author:
Xiaoming Wang; Jingwei Zheng; Lei Guo; Hao Yao; Lingya Wang; XiaoDong Xia; Weixi Zhang
Source:
Virus research 2020 v.289 pp. 198147
ISSN:
0168-1702
Subject:
viral shedding,   etc   ; C-reactive protein; COVID-19 infection; RNA; Severe acute respiratory syndrome coronavirus 2; chest; feces; fibrinogen; image analysis; patients; viral load;     Show all 11 Subjects
Abstract:
... To investigate the clinical significance, viral shedding duration and viral load dynamics of positive fecal SARS-CoV-2 signals in COVID-19.COVID-19 patients were included. SARS-CoV-2 RNA was tested in stool and respiratory specimens until two sequential negative results were obtained. Clinical, laboratory and imaging data were recorded.Of the 69 COVID-19 patients, 20 (28.99 %) had positive fecal v ...
DOI:
10.1016/j.virusres.2020.198147

13. Shedding of oral pentavalent bovine-human reassortant rotavirus vaccine indicates high uptake rate of vaccine and prominence of G-type G1

Author:
Jukka Markkula; Maria Hemming-Harlo; Timo Vesikari
Source:
Vaccine 2020 v.38 no.6 pp. 1378-1383
ISSN:
0264-410X
Subject:
viral shedding,   etc   ; Rotavirus; feces; genotype; humans; immunity; infants; parents; reverse transcriptase polymerase chain reaction; signs and symptoms (animals and humans); vaccination; vaccines; virion; viruses;     Show all 14 Subjects
Abstract:
... Live oral pentavalent bovine-human reassortant rotavirus (RV) vaccine, RotaTeq®, contains bovine rotaviruses reassorted with human G-types G1, G2, G3 and G4, and P-type P[8]. Shedding of RotaTeq® vaccine, as studied by RT-PCR, has been shown to be more common than initially reported, and may include formation of vaccine-derived double-reassortant G1P[8] RVs. We studied the extent and duration of R ...
DOI:
10.1016/j.vaccine.2019.12.007

14. Maternally Derived Antibody Levels Influence on Vaccine Protection against PCV2d Challenge

Author:
István Kiss; Krisztina Szigeti; Zalán G. Homonnay; Vivien Tamás; Han Smits; Roman Krejci
Source:
Animals 2021 v.11 no.8 pp. -
ISSN:
2076-2615
Subject:
viral shedding,   etc   ; Porcine circovirus-2; humoral immunity; immune response; maternal immunity; piglets; subunit vaccines; vaccination; viral antibodies; viral antigens; viral load; viral vaccines; viremia;     Show all 13 Subjects
Abstract:
... Piglets from a porcine circovirus type 2 (PCV2) stable farm of low and high levels of maternally derived antibodies (MDA) against PCV2 were vaccinated either with a whole virus type or a PCV2 ORF2 antigen-based commercial subunit vaccine at three weeks of age. Two non-vaccinated groups served as low and high MDA positive controls. At four weeks post vaccination, all piglets were challenged with a ...
DOI:
10.3390/ani11082231

15. High-Resolution Composition Analysis of an Inactivated Polyvalent Foot-and-Mouth Disease Vaccine

Author:
Leonie F. Forth; Dirk Höper; Martin Beer; Michael Eschbaumer
Source:
Pathogens 2020 v.9 no.1 pp. -
ISSN:
2076-0817
Subject:
viral shedding,   etc   ; cross immunity; decision making; foot-and-mouth disease; genome; genome assembly; high-throughput nucleotide sequencing; nucleotide sequences; pathogens; serotypes; testing; vaccination; vaccines;     Show all 13 Subjects
Abstract:
... Appropriate vaccine selection is crucial in the control of foot-and-mouth disease (FMD). Vaccination can prevent clinical disease and reduces viral shedding, but there is a lack of cross-protection between the seven serotypes and their sublineages, making the selection of an adequately protective vaccine difficult. Since the exact composition of their vaccines is not consistently disclosed by all ...
DOI:
10.3390/pathogens9010063

16. Oral Mutian®X stopped faecal feline coronavirus shedding by naturally infected cats

Author:
Diane D. Addie; Sheryl Curran; Flora Bellini; Ben Crowe; Emily Sheehan; Lesya Ukrainchuk; Nicola Decaro
Source:
Research in veterinary science 2020 v.130 pp. 222-229
ISSN:
0034-5288
Subject:
viral shedding,   etc   ; animal viruses; cats; feces; feline infectious peritonitis; guidelines; households; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; reverse transcription; virus transmission; viruses;     Show all 12 Subjects
Abstract:
... Feline coronavirus (FCoV) is common among cats living indoors in groups. In about 10% of infected cats, a potentially lethal disease, feline infectious peritonitis (FIP) occurs. Virus transmission is faecal-oral. Mutian® Xraphconn (Mutian X) is a product marketed to treat cats with FIP but is also being used to stop virus shedding, although no clear guidelines exist for its use for this purpose. T ...
DOI:
10.1016/j.rvsc.2020.02.012
PubMed:
32220667
PubMed Central:
PMC7102653

17. SARS-CoV-2-specific ELISA development

Author:
Vicky Roy; Stephanie Fischinger; Caroline Atyeo; Matthew Slein; Carolin Loos; Alejandro Balazs; Corinne Luedemann; Michael Gerino Astudillo; Diane Yang; Duane R. Wesemann; Richelle Charles; A. John Lafrate; Jared Feldman; Blake Hauser; Tim Caradonna; Tyler E. Miller; Mandakolathur R. Murali; Lindsey Baden; Eric Nilles; Edward Ryan; Douglas Lauffenburger; Wilfredo Garcia Beltran; Galit Alter
Source:
Journal of immunological methods 2020 v.484-485 pp. 112832
ISSN:
0022-1759
Subject:
viral shedding,   etc   ; COVID-19 infection; RNA; Severe acute respiratory syndrome coronavirus 2; adaptive immunity; antibodies; enzyme-linked immunosorbent assay; genomics; respiratory system; virus replication; viruses;     Show all 11 Subjects
Abstract:
... Critical to managing the spread of COVID-19 is the ability to diagnose infection and define the acquired immune response across the population. While genomic tests for the novel Several Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) detect the presence of viral RNA for a limited time frame, when the virus is shed in the upper respiratory tract, tests able to define exposure and infection be ...
DOI:
10.1016/j.jim.2020.112832

18. Detection of Human Papillomaviruses in the Nasopharynx of Breastfed Infants: New Findings and Meta-Analysis

Author:
Luisa Dassi; Clorinda Annunziata; Chiara Botti; Alberto Micillo; Andrea Cerasuolo; Noemy Starita; Franco M. Buonaguro; Maria Lina Tornesello
Source:
Viruses 2020 v.12 no.10 pp. -
ISSN:
1999-4915
Subject:
viral shedding,   etc   ; animal viruses; breast feeding; breast milk; breasts; children; epithelium; genotype; meta-analysis; nasopharynx; neonates; oligodeoxyribonucleotides; papilloma; polymerase chain reaction; respiratory tract diseases; sequence analysis;     Show all 16 Subjects
Abstract:
... Vertical transmission of human papillomaviruses (HPVs) from mother to infant is known to occur during labor, delivery or breastfeeding. Infection with mucosal HPV 6 and 11 may cause recurrent respiratory papillomatosis in children, which is a rare and severe respiratory disease. The cutaneous HPV genotypes have also been described to be transmitted from mother to newborn through skin-to-skin conta ...
DOI:
10.3390/v12101119

19. A vaccine containing highly purified virus particles in adjuvant provides high level protection against genital infection and disease in guinea pigs challenged intravaginally with homologous and heterologous strains of herpes simplex virus type 2

Author:
David I. Bernstein; Christopher S. Morello; Rhonda D. Cardin; Fernando J. Bravo; Kimberly A. Kraynyak; Deborah H. Spector
Source:
Vaccine 2020 v.38 no.1 pp. 79-89
ISSN:
0264-410X
Subject:
viral shedding,   etc   ; DNA; Human alphaherpesvirus 2; Human immunodeficiency virus; adjuvants; animal diseases; ganglia; glycoproteins; guinea pigs; herpes simplex; humans; lipid A; models; vaccination; vaccines; virion; viruses;     Show all 17 Subjects
Abstract:
... Infection with Herpes Simplex Viruses (HSVs) represents a significant health burden worldwide with HSV-1 and HSV-2 causing genital disease and HSV-2 contributing to human immunodeficiency virus acquisition. Despite great need, there is currently no licensed vaccine against HSV. In this report, we evaluated the protective efficacy of a vaccine containing highly purified, inactivated HSV-2 particles ...
DOI:
10.1016/j.vaccine.2019.09.090

20. Evaluation of the safety and protection efficacy of an attenuated genotype vii newcastle disease virus strain as a candidate vaccine

Author:
Xiaohong Xu; Jindou Li; Jiaxin Ding; Mingxi Yang; Cong Xue; Jianzhong Wang; Yanlong Cong; Renfu Yin; Jing Qian; Ningyi Jin; Zhuang Ding
Source:
Microbial pathogenesis 2020 v.139 pp. 103831
ISSN:
0882-4010
Subject:
viral shedding,   etc   ; Avian orthoavulavirus 1; Newcastle disease; antibodies; blood serum; chicken eggs; chickens; financial economics; genetic distance; genotype; signs and symptoms (animals and humans); vaccination; vaccines; virulence;     Show all 14 Subjects
Abstract:
... Newcastle disease (ND) is a serious avian infectious disease, causing severe economic loss worldwide. Its prevention depends on comprehensive vaccination scheme against Newcastle disease virus (NDV). However, current vaccine strains are of different genotypes with prevalent circulating strains (genotype VII), with significant genetic distance. Our team previously generated a genotype matched atten ...
DOI:
10.1016/j.micpath.2019.103831