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1. Retraction notice to “Mycoplasma synoviae vaccine modifies virus shedding and immune responses of avian influenza (H9N2) infection in commercial layers” [Poult. Sci. 96 (2017) 3086–3095]

Author:
Umar, Sajid; Tanweer, Muhammad; Iqbal, Mudassar; Shahzad, Asad; Hassan, Farooq; Usman, Muhammad; Sarwar, Fozia; Qadir, Hajra; Asif, Sajjad; Qamar, un-Nisa; Younus, Muhammad; Ali, Asif; Akbar, Mehboob; Towakal, Farhan; Shah, Muhammad Ali
Source:
Poultry science 2020 v.99 no.8 pp. R4102
ISSN:
0032-5791
Subject:
viral shedding,   etc   ; Mycoplasma synoviae; avian influenza; immune response; issues and policy; poults; vaccines;     Show all 7 Subjects
Abstract:
... This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).The authors retract the above paper due to: 1) conflict of interest among the authors; and 2) addition of co-author Dr. Muhammad Younus without his knowledge or permission. The authors apologize for these two grave mistakes. ...
DOI:
10.1016/j.psj.2020.07.002

2. Genetic and antigenic heterogeneity of GI-1/Massachusetts lineage infectious bronchitis virus variants recently isolated in China

Author:
Sheng, Jie; Ren, Mengting; Han, Zongxi; Sun, Junfeng; Zhao, Yan; Liu, Shengwang
Source:
Poultry science 2020 v.99 no.11 pp. 5440-5451
ISSN:
0032-5791
Subject:
viral shedding,   etc   ; Infectious bronchitis virus; amino acids; chickens; evolution; flocks; genome; live vaccines; mutation; neutralization tests; pathogenicity; reverse genetics; China;     Show all 13 Subjects
Abstract:
... Four GI-1/Massachusetts-type (GI-1/Mass-type) infectious bronchitis virus (IBV) strains were isolated and the complete genomes of these isolates, coupled with the Mass-type live-attenuated vaccine H120 and the Mass-type pathogenic M41 strains, were sequenced in the present study. Our results show that isolates LJL/140820 and I0306/17 may be derived from the Ma5 (another Mass-type live-attenuated v ...
DOI:
10.1016/j.psj.2020.08.037

3. SARS-CoV-2 RNA Persistence in Naso-Pharyngeal Swabs

Author:
Danzetta, Maria Luisa; Amato, Laura; Cito, Francesca; Di Giuseppe, Alessandra; Morelli, Daniela; Savini, Giovanni; Mercante, Maria Teresa; Lorusso, Alessio; Portanti, Ottavio; Puglia, Ilaria; Monaco, Federica; Casaccia, Claudia; Di Gennaro, Annapia; Testa, Lilia; Migliorati, Giacomo; D’Alterio, Nicola; Calistri, Paolo
Source:
Microorganisms 2020 v.8 no.8
ISSN:
2076-2607
Subject:
viral shedding,   etc   ; RNA; Severe acute respiratory syndrome coronavirus 2; health services; men; monitoring; pandemic; patients; viruses; Italy;     Show all 10 Subjects
Abstract:
... Since February 2020, Italy has been seriously affected by the SARS-CoV-2 pandemic. To support the National Health Care system, naso-pharyngeal/oropharyngeal swabs collected from suspected cases of Teramo province, Abruzzo region, are tested at Istituto Zooprofilattico Sperimentale dell’Abruzzo e del Molise G. Caporale, for the presence of SARS-CoV-2 RNA. Out of 12,446 tested individuals, 605 retur ...
DOI:
10.3390/microorganisms8081124

4. Conserved HA-peptides expressed along with flagellin in Trichoplusia ni larvae protects chicken against intranasal H7N1 HPAIV challenge

Author:
Sisteré-Oró, Marta; Martínez-Pulgarín, Susana; Solanes, David; Veljkovic, Veljko; López-Serrano, Sergi; Córdoba, Lorena; Cordón, Ivan; Escribano, José M.; Darji, Ayub
Source:
Vaccine 2020 v.38 no.3 pp. 416-422
ISSN:
0264-410X
Subject:
viral shedding,   etc   ; Baculoviridae; Orthomyxoviridae; Trichoplusia ni; chickens; epitopes; flagellin; immune response; immunization; signs and symptoms (animals and humans); vaccines; zoonoses;     Show all 12 Subjects
Abstract:
... The immunization of poultry where H5 and H7 influenza viruses (IVs) are endemic is one of the strategies to prevent unexpected zoonoses. Our group has been focused on conserved HA-epitopes as potential vaccine candidates to obtain multivalent immune responses against distinct IV subtypes. In this study, two conserved epitopes (NG-34 and CS-17) fused to flagellin were produced in a Baculovirus plat ...
DOI:
10.1016/j.vaccine.2019.11.006

5. A class Ⅰ lentogenic newcastle disease virus strain confers effective protection against the prevalent strains

Author:
Li, Shu-yun; You, Guo-jin; Du, Ji-teng; Xia, Jing; Wen, Yi-ping; Huang, Xiao-bo; Zhao, Qing; Han, Xin-feng; Yan, Qi-gui; Wu, Rui; Cao, San-jie; Huang, Yong
Source:
Biologicals 2020 v.63 pp. 74-80
ISSN:
1045-1056
Subject:
viral shedding,   etc   ; Avian orthoavulavirus 1; antiserum; chickens; genotype; humoral immunity; serotypes; signs and symptoms (animals and humans); vaccines;     Show all 9 Subjects
Abstract:
... The traditional vaccine strains, such as LaSota, do not completely prevent the shedding of NDV. An ideal vaccine which could not only prevent the clinical signs, but significantly reduce the shedding of NDV is urgently needed for the eradication of ND. In this study, an NDV isolate APMV-1/Chicken/China (SC)/PT3/2016 (hereafter referred as PT3) was identified as a class Ⅰ NDV and a lentogenic strai ...
DOI:
10.1016/j.biologicals.2019.11.001

6. Horizontal transmission of foot‐and‐mouth disease virus O/JPN/2010 among different animal species by direct contact

Author:
Fukai, Katsuhiko; Nishi, Tatsuya; Morioka, Kazuki; Yamada, Manabu; Yoshida, Kazuo; Yamakawa, Makoto
Source:
Transboundary and emerging diseases 2020 v.67 no.1 pp. 223-233
ISSN:
1865-1674
Subject:
viral shedding,   etc   ; Foot-and-mouth disease virus; cows; disease transmission; emerging diseases; farms; foot-and-mouth disease; goats; swine;     Show all 9 Subjects
Abstract:
... Foot‐and‐mouth disease (FMD) is highly contagious and easily transmitted among species of cloven‐hoofed animals. To investigate the transmission of FMD virus (FMDV) among different animal species, experimental infections using the O/JPN/2010 strain were performed in cows, goats and pigs. One cow or two goats/pigs were housed with a different species of inoculated animals, and clinical observations ...
DOI:
10.1111/tbed.13344

7. Fecal viral shedding in COVID-19 patients: Clinical significance, viral load dynamics and survival analysis

Author:
Wang, Xiaoming; Zheng, Jingwei; Guo, Lei; Yao, Hao; Wang, Lingya; Xia, XiaoDong; Zhang, Weixi
Source:
Virus research 2020 v.289 pp. 198147
ISSN:
0168-1702
Subject:
viral shedding,   etc   ; C-reactive protein; COVID-19 infection; RNA; Severe acute respiratory syndrome coronavirus 2; chest; feces; fibrinogen; image analysis; patients; viral load;     Show all 11 Subjects
Abstract:
... To investigate the clinical significance, viral shedding duration and viral load dynamics of positive fecal SARS-CoV-2 signals in COVID-19.COVID-19 patients were included. SARS-CoV-2 RNA was tested in stool and respiratory specimens until two sequential negative results were obtained. Clinical, laboratory and imaging data were recorded.Of the 69 COVID-19 patients, 20 (28.99 %) had positive fecal v ...
DOI:
10.1016/j.virusres.2020.198147

8. Comparative pathogenicity of two closely related Newcastle disease virus isolates from chicken and pigeon respectively

Author:
Zhan, Tiansong; Hu, Shunlin; Chen, Yu; Lu, Xiaolong; Liao, Tianxing; Guo, Lili; Gao, Xiaomin; Xu, Xiaoting; Hu, Zenglei; Liu, Xiaowen; Wang, Xiaoquan; Liu, Xiufan
Source:
Virus research 2020 v.286 pp. 198091
ISSN:
0168-1702
Subject:
viral shedding,   etc   ; Avian orthoavulavirus 1; Newcastle disease; Respirovirus; chick embryos; chickens; chicks; death; morbidity; mortality; phylogeny; pigeons; signs and symptoms (animals and humans); virulence; viruses; Kuwait;     Show all 16 Subjects
Abstract:
... Newcastle disease (ND), caused by virulent Newcastle disease virus (NDV), is a highly contagious disease that has led to tremendous economic losses worldwide. Pigeon paramyxovirus type 1 (PPMV-1) is an antigenic and host variant of NDV. However, limited in-depth studies are available concerning side-by-side comparison of pathogenicity of PPMV-1 and its phylogenetically close NDV both in chickens a ...
DOI:
10.1016/j.virusres.2020.198091

9. Novel goose-origin astrovirus infection in geese: the effect of age at infection

Author:
An, Da; Zhang, Ji; Yang, Jing; Tang, Yi; Diao, Youxiang
Source:
Poultry science 2020 v.99 no.9 pp. 4323-4333
ISSN:
0032-5791
Subject:
viral shedding,   etc   ; RNA; cytokines; death; goslings; gout; histopathology; infectious diseases; kidneys; liver; pathogens; poultry diseases; signs and symptoms (animals and humans); China;     Show all 14 Subjects
Abstract:
... Since 2017, a serious infectious disease characterized by visceral gout has emerged in China's main goose-producing regions. The disease has caused huge economic losses to China's goose industry. In our previous study, we determined that the pathogen causing gout in goslings is a novel goose-origin astrovirus, designated as AStV/SDPY/Goose/1116/17 (AStV-SDPY) strain. To investigate the effect of h ...
DOI:
10.1016/j.psj.2020.05.041

10. Characterization, pathogenicity and protective efficacy of a cell culture-derived porcine deltacoronavirus

Author:
Gao, Xiang; Zhao, Donghong; Zhou, Peng; Zhang, Liping; Li, Mingxia; Li, Weiyan; Zhang, Yongguang; Wang, Yonglu; Liu, Xinsheng
Source:
Virus research 2020 v.282 pp. 197955
ISSN:
0168-1702
Subject:
viral shedding,   etc   ; Coronavirinae; adjuvants; animal viruses; diarrhea; financial economics; genes; humoral immunity; inactivated vaccines; mutation; pathogenicity; piglets; protective effect; suckling; swine diseases; China; United States;     Show all 17 Subjects
Abstract:
... Porcine deltacoronavirus (PDCoV) is a novel swine enteropathogenic coronavirus that causes acute diarrhea, vomiting, dehydration and mortality in neonatal piglets, resulting in significant economic losses to the pig industry. However, there is currently little information on vaccine studies and commercially available vaccines for PDCoV. Hence, herein, a PDCoV strain, CH/XJYN/2016, was successfully ...
DOI:
10.1016/j.virusres.2020.197955
PubMed:
32247757
PubMed Central:
PMC7125813

11. Identification and pathogenicity of a novel genotype avian hepatitis E virus from silkie fowl (gallus gallus)

Author:
Liu, Baoyuan; Chen, Yiyang; Zhao, Liang; Zhang, Meimei; Ren, Xiaolei; Zhang, Yuan; Zhang, Beibei; Fan, Mengnan; Zhao, Qin; Zhou, En-Min
Source:
Veterinary microbiology 2020 v.245 pp. 108688
ISSN:
0378-1135
Subject:
viral shedding,   etc   ; Gallus gallus; Orthohepevirus A; Orthohepevirus B; alanine transaminase; amino acids; chickens; endoplasmic reticulum; genetic variation; genome; genotype; hosts; liver; mitochondria; pathogenicity; public health; seroconversion; viremia; zoonoses;     Show all 19 Subjects
Abstract:
... Hepatitis E virus (HEV) is a public health concern because of its zoonotic potential; however, the host species spectrum and the genetic diversity of HEV in many birds are unknown. In the present study, a novel genotype avian HEV was isolated from a bird, silkie fowl, and designated CHN-GS-aHEV (GenBank No. MN562265). The genome of CHN-GS-aHEV was analyzed in comparison with other avian HEVs’ and ...
DOI:
10.1016/j.vetmic.2020.108688

12. Oral Mutian®X stopped faecal feline coronavirus shedding by naturally infected cats

Author:
Addie, Diane D.; Curran, Sheryl; Bellini, Flora; Crowe, Ben; Sheehan, Emily; Ukrainchuk, Lesya; Decaro, Nicola
Source:
Research in veterinary science 2020 v.130 pp. 222-229
ISSN:
0034-5288
Subject:
viral shedding,   etc   ; animal viruses; cats; feces; feline infectious peritonitis; guidelines; households; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; reverse transcription; virus transmission; viruses;     Show all 12 Subjects
Abstract:
... Feline coronavirus (FCoV) is common among cats living indoors in groups. In about 10% of infected cats, a potentially lethal disease, feline infectious peritonitis (FIP) occurs. Virus transmission is faecal-oral. Mutian® Xraphconn (Mutian X) is a product marketed to treat cats with FIP but is also being used to stop virus shedding, although no clear guidelines exist for its use for this purpose. T ...
DOI:
10.1016/j.rvsc.2020.02.012
PubMed:
32220667
PubMed Central:
PMC7102653

13. Process development for quantitation and vaccine efficacy assessment of recombinant hemagglutinin-neuraminidase

Author:
Lye, Ping Ying; Noor, Suriani Mohd; Shohaimi, Syamsiah Aini; Junoh, Niny Fariza; Tan, Soo Choon; Iwamoto, Shinichi; Kotani, Eiji; Norazmi, Mohd Nor; Nagamine, Toshihiro; Mori, Hajime; Liew, Mervyn W.O.
Source:
Process biochemistry 2020 v.90 pp. 204-214
ISSN:
1359-5113
Subject:
viral shedding,   etc   ; Avian orthoavulavirus 1; antibodies; antibody formation; cell culture; chickens; chromatography; detergents; enzyme-linked immunosorbent assay; enzymes; hemagglutination; herd immunity; insects; manufacturing; reference standards; subunit vaccines;     Show all 16 Subjects
Abstract:
... Recombinant hemagglutinin-neuraminidase (HN) based subunit vaccine, which is non-infectious and can be produced using insect cell-culture systems, is a potential alternative to conventional live and inactivated Newcastle disease virus (NDV) vaccines. However, process development for manufacture and efficacy assessment of HN subunit vaccines has been hampered by the absence of reference standards, ...
DOI:
10.1016/j.procbio.2019.11.018

14. Protection of chickens against hepatitis-hydropericardium syndrome and Newcastle disease with a recombinant Newcastle disease virus vaccine expressing the fowl adenovirus serotype 4 fiber-2 protein

Author:
Tian, Kai-yue; Guo, Hui-Fang; Li, Ning; Zhang, Yu-han; Wang, Zeng; Wang, Baiyu; Yang, Xia; Li, Yong-tao; Zhao, Jun
Source:
Vaccine 2020 v.38 no.8 pp. 1989-1997
ISSN:
0264-410X
Subject:
viral shedding,   etc   ; Adenoviridae; Avian orthoavulavirus 1; Newcastle disease; White Leghorn; chickens; chicks; drinking water; economic impact; eggs; genes; inactivated vaccines; poultry industry; reverse genetics; serotypes; vaccination; virulence; viruses;     Show all 18 Subjects
Abstract:
... Newcastle disease (ND) is one of the most important and devastating avian diseases with considerable threat to the global poultry industry. Hepatitis-hydropericardium syndrome (HHS), caused by virulent fowl adenovirus serotype 4 (FAdV-4), is another highly infectious disease in chickens with severe economic impact. The effective way to combat ND and HHS is by vaccinating the poultry. In the presen ...
DOI:
10.1016/j.vaccine.2020.01.006

15. Shedding of oral pentavalent bovine-human reassortant rotavirus vaccine indicates high uptake rate of vaccine and prominence of G-type G1

Author:
Markkula, Jukka; Hemming-Harlo, Maria; Vesikari, Timo
Source:
Vaccine 2020 v.38 no.6 pp. 1378-1383
ISSN:
0264-410X
Subject:
viral shedding,   etc   ; Rotavirus; feces; genotype; humans; immunity; infants; parents; reverse transcriptase polymerase chain reaction; signs and symptoms (animals and humans); vaccination; vaccines; virion; viruses;     Show all 14 Subjects
Abstract:
... Live oral pentavalent bovine-human reassortant rotavirus (RV) vaccine, RotaTeq®, contains bovine rotaviruses reassorted with human G-types G1, G2, G3 and G4, and P-type P[8]. Shedding of RotaTeq® vaccine, as studied by RT-PCR, has been shown to be more common than initially reported, and may include formation of vaccine-derived double-reassortant G1P[8] RVs. We studied the extent and duration of R ...
DOI:
10.1016/j.vaccine.2019.12.007

16. Evaluation of the safety and protection efficacy of an attenuated genotype vii newcastle disease virus strain as a candidate vaccine

Author:
Xu, Xiaohong; Li, Jindou; Ding, Jiaxin; Yang, Mingxi; Xue, Cong; Wang, Jianzhong; Cong, Yanlong; Yin, Renfu; Qian, Jing; Jin, Ningyi; Ding, Zhuang
Source:
Microbial pathogenesis 2020 v.139 pp. 103831
ISSN:
0882-4010
Subject:
viral shedding,   etc   ; Avian orthoavulavirus 1; Newcastle disease; antibodies; blood serum; chicken eggs; chickens; financial economics; genetic distance; genotype; signs and symptoms (animals and humans); vaccination; vaccines; virulence;     Show all 14 Subjects
Abstract:
... Newcastle disease (ND) is a serious avian infectious disease, causing severe economic loss worldwide. Its prevention depends on comprehensive vaccination scheme against Newcastle disease virus (NDV). However, current vaccine strains are of different genotypes with prevalent circulating strains (genotype VII), with significant genetic distance. Our team previously generated a genotype matched atten ...
DOI:
10.1016/j.micpath.2019.103831

17. Improved foot-and-mouth disease vaccine with O PanAsia-2 strain protect pigs against O/Jincheon/SKR/2014 originated from South Korea

Author:
Ko, Mi-Kyeong; Jo, Hye-Eun; Choi, Joo-Hyung; You, Su-Hwa; Shin, Sung Ho; Jo, Hyundong; Lee, Min Ja; Kim, Su-Mi; Kim, Byounghan; Park, Jong-Hyeon
Source:
Vaccine 2020 v.38 no.5 pp. 1120-1128
ISSN:
0264-410X
Subject:
viral shedding,   etc   ; antibody formation; cattle; foot-and-mouth disease; neutralization; neutralizing antibodies; swine; swine diseases; vaccination; vaccine development; vaccines; viruses; South Korea;     Show all 13 Subjects
Abstract:
... Efforts are required to develop foot-and-mouth disease (FMD) vaccines in Asia that can respond to the type O outbreaks that have continued with the devastating damage since 2010. It is necessary to develop vaccine strains that can provide protection against the ME-SA topotype, which has tended to spread into neighboring areas, and the frequent SEA topotype outbreaks. To this end, this study aimed ...
DOI:
10.1016/j.vaccine.2019.11.029

18. A vaccine containing highly purified virus particles in adjuvant provides high level protection against genital infection and disease in guinea pigs challenged intravaginally with homologous and heterologous strains of herpes simplex virus type 2

Author:
Bernstein, David I.; Morello, Christopher S.; Cardin, Rhonda D.; Bravo, Fernando J.; Kraynyak, Kimberly A.; Spector, Deborah H.
Source:
Vaccine 2020 v.38 no.1 pp. 79-89
ISSN:
0264-410X
Subject:
viral shedding,   etc   ; DNA; Human alphaherpesvirus 2; Human immunodeficiency virus; adjuvants; animal diseases; ganglia; glycoproteins; guinea pigs; herpes simplex; humans; lipid A; models; vaccination; vaccines; virion; viruses;     Show all 17 Subjects
Abstract:
... Infection with Herpes Simplex Viruses (HSVs) represents a significant health burden worldwide with HSV-1 and HSV-2 causing genital disease and HSV-2 contributing to human immunodeficiency virus acquisition. Despite great need, there is currently no licensed vaccine against HSV. In this report, we evaluated the protective efficacy of a vaccine containing highly purified, inactivated HSV-2 particles ...
DOI:
10.1016/j.vaccine.2019.09.090

19. Genotypes II and VIId-based inactivated Newcastle disease vaccine reduces virus shedding

Author:
Mahmoud, Nehal K.; El-Deeb, Ayman H.; Emara, Mohammed M.; Abd El-Khaleck, M. A.; Hussein, Hussein A.
Source:
Virusdisease 2019 v.30 no.3 pp. 453-461
ISSN:
2347-3584
Subject:
viral shedding,   etc   ; Avian orthoavulavirus 1; Newcastle disease; chickens; chicks; flocks; genotype; hemagglutination; histopathology; neutralization; vaccines; Egypt;     Show all 12 Subjects
Abstract:
... In Egypt, recent outbreaks were reported in NDV-vaccinated flocks. The isolated strain was characterized as class II velogenic genotype VIId of Newcastle disease virus (NDV). In this study, three inactivated NDV vaccine formulations were prepared, the first one is LaSota (genotype II), the second one is genotype VIId and the third one is combined Lasota and genotype VIId at a proportion of 1:1. Th ...
DOI:
10.1007/s13337-019-00537-2
PubMed:
31803813
PubMed Central:
PMC6864008

20. Incorporation of a truncated form of flagellin (TFlg) into porcine circovirus type 2 virus-like particles enhances immune responses in mice

Author:
Liu, Xiangyu; Liu, Yangkun; Zhang, Yuanyuan; Zhang, Fan; Du, Enqi
Source:
BMC veterinary research 2020 v.16 no.1 pp. 45
ISSN:
1746-6148
Subject:
viral shedding,   etc   ; Escherichia coli; Porcine circovirus-2; Western blotting; adjuvants; cell-mediated immunity; coat proteins; disease control; flagellin; immune response; pathogens; pork industry; recombinant proteins; vaccination; vaccines; viral load; viremia; virus-like particles;     Show all 18 Subjects
Abstract:
... BACKGROUND: Porcine circovirus type 2 (PCV2) is an economically important pathogen in the swine industry worldwide. Vaccination remains the principal tool to control PCV2-associated diseases (PCVADs). Current vaccines do not eliminate viral shedding in the environment. To enhance the efficacy of PCV2 vaccines, recombinant virus-like particles (VLPs) of PCV2 were generated by fusing a truncated for ...
DOI:
10.1186/s12917-020-2253-6
PubMed:
32028949
PubMed Central:
PMC7006081