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1. Monitoring of porcine circovirus type 2 infection through air and surface samples in vaccinated and unvaccinated fattening farms

Author:
Gonzalo López‐Lorenzo; Cynthia López‐Novo; Alberto Prieto; Pablo Díaz; Rosario Panadero; Víctor Rodríguez‐Vega; Patrocinio Morrondo; Gonzalo Fernández; José Manuel Díaz‐Cao
Source:
Transboundary and emerging diseases 2022 v.69 no.3 pp. 1108-1117
ISSN:
1865-1674
Subject:
viremia,   etc   ; Porcine circovirus-2; air; blood; health status; herds; swine; viral load; viruses;     Show all 9 Subjects
Abstract:
... Air and surfaces of swine farms are the two alternative samples to obtain information about the health status of the herd. The aim of this study was to assess air and surface sampling for the detection of porcine circovirus type 2 (PCV2) in vaccinated and unvaccinated fattening farms, studying the relationship between the viral load in these samples with the viremia at herd level. Three swine fatt ...
DOI:
10.1111/tbed.14069

2. Recurrent parvovirus B19 viremia resulting in two episodes of hemophagocytic lymphohistiocytosis

Author:
Hans Martin Orth; Andre Fuchs; Nadine Lübke; Björn-Erik Ole Jensen; Tom Luedde
Source:
Virology journal 2022 v.19 no.1 pp. 107
ISSN:
1743-422X
Subject:
viremia,   etc   ; Protoparvovirus; adrenal cortex hormones; females; fever; immunity; immunoglobulins; intravenous injection; macrophages; patients; virology;     Show all 11 Subjects
Abstract:
... BACKGROUND: Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory condition with uncontrolled activation of lymphocytes and macrophages. Besides a primary (genetic) form, HLH can also be triggered by malignant, autoimmune and infectious diseases. HLH recurrences are rarely described, usually only in primary HLH. Parvovirus B19 (PVB19) Infection is one of the rare and rather benign causes ...
DOI:
10.1186/s12985-022-01841-y

3. Low-level viraemia and virologic failure among people living with HIV who received maintenance therapy with co-formulated bictegravir, emtricitabine and tenofovir alafenamide versus dolutegravir-based regimens

Author:
Guan-Jhou Chen; Hsin-Yun Sun; Ling-Ya Chen; Szu-Min Hsieh; Wang-Hui Sheng; Wang-Da Liu; Yu-Chung Chuang; Yu-Shan Huang; Kuan-Yin Lin; Pei-Ying Wu; Hsi-Yen Chang; Yu-Zhen Luo; Yi-Ching Su; Wen-Chun Liu; Sui-Fang Chang; Sui-Yuan Chang; Chien-Ching Hung
Source:
International journal of antimicrobial agents 2022 pp. 106631
ISSN:
0924-8579
Subject:
viremia,   etc   ; RNA; antiretroviral agents; cohort studies; confidence interval; integrases; multivariate analysis; nucleosides; people; therapeutics;     Show all 10 Subjects
Abstract:
... Real-world experience with low-level viraemia (LLV) and its impact remain less reported among people living with HIV (PLWH) who receive antiretroviral therapy (ART) containing second-generation integrase strand transferase inhibitors, including dolutegravir and bictegravir. This retrospective cohort study included virally suppressed PLWH who achieved plasma HIV-RNA viral load (PVL) <50 copies/mL f ...
DOI:
10.1016/j.ijantimicag.2022.106631

4. Heterologous Challenge with PRRSV-1 MLV in Pregnant Vaccinated Gilts: Potential Risk on Health and Immunity of Piglets

Author:
Georgios Papakonstantinou; Eleftherios Meletis; Georgios Christodoulopoulos; Eleni D. Tzika; Polychronis Kostoulas; Vasileios G. Papatsiros
Source:
Animals 2022 v.12 no.4 pp. -
ISSN:
2076-2615
Subject:
viremia,   etc   ; Betaarterivirus suid 1; farms; health status; immunity; markets; phylogeny; pregnancy; risk; vaccination; vaccines; viruses;     Show all 12 Subjects
Abstract:
... The objective of the present study was to evaluate the potential risks of the four commercial PRRS-1 MLV vaccines in pregnant vaccinated gilts at the last stage of gestation under field conditions. The study was conducted at four pig farms, including 25 gilts from each farm (25 × 4 = 100 gilts), which were equally allocated to five different study groups. A PRRS-1 MLV vaccination was applied on th ...
DOI:
10.3390/ani12040450

5. Comparative efficacy evaluation of different CSF vaccines in pigs with CSF maternally derived antibodies

Author:
Ning Chen; Qin Wang; Yulong Hu; Yanyong Sun; Junping Li; Huawei Wu; Lu Xu; Huanhuan Liu; Chenghuai Yang; Xiaochun Chen; Yong Deng; Yingju Xia; Qianyi Zhang; Shi Cheng; Aihua Fan; Guanghua Chen
Source:
Veterinary microbiology 2022 pp. 109541
ISSN:
0378-1135
Subject:
viremia,   etc   ; antibodies; death; fever; hog cholera; immunity; microbiology; monitoring; secondary immunization; swine; vaccination; vaccines; China;     Show all 13 Subjects
Abstract:
... Classical swine fever (CSF) is a highly contagious and important swine disease in China. Sporadic outbreaks with mild clinical signs are still being reported despite massive vaccination with the CSF C-strain vaccine. One possible reason for vaccine failure could be interference from maternally derived antibodies (MDAs) during vaccination in the field. The aim of this study was to evaluate the effi ...
DOI:
10.1016/j.vetmic.2022.109541

6. Isolation, identification and pathogenicity of a ALV-K strain from Chinese indigenous chicken breed

Author:
Hao Chen; Youjiang Diao; Xiaolong Sun; Yixin Wang
Source:
Poultry science 2022 pp. 102116
ISSN:
0032-5791
Subject:
viremia,   etc   ; Avian leukosis virus; chickens; genes; growth retardation; immune response; nucleotide sequences; pathogenicity; yolk sac; China;     Show all 10 Subjects
Abstract:
... Subgroup K avian leukosis virus (ALV-K) is a new subgroup of avian leukosis virus (ALV) first identified in Chinese indigenous chickens in recent years. In this study, an ALV-K strain was isolated from Luhua chicken in Shandong province, China, and designated SD20LH01. The full-length genomic sequence of SD20LH01 was 7491 bp, which had the highest homology with ALV-K reference strains GDFX0601, GD ...
DOI:
10.1016/j.psj.2022.102116

7. Persistence and shedding of senecavirus A in naturally infected boars

Author:
Matthew J. Sturos; Deborah Murray; Levi Johnson; Guilherme Preis; Cesar A. Corzo; Stephanie Rossow; Fabio A. Vannucci
Source:
Journal of veterinary diagnostic investigation 2022 v.34 no.3 pp. 474-481
ISSN:
1943-4936
Subject:
viremia,   etc   ; Senecavirus A; adults; atrophy; boars; epithelium; farms; feces; fibrosis; histiocytes; orchitis; semen; tonsils; viruses; Indiana; Minnesota;     Show all 16 Subjects
Abstract:
... Senecavirus A (SVA) infection in pigs causes vesicular disease and results in a short viremia and transient shedding of the virus, mainly in oral fluids and feces. Here we describe the consistent prolonged shedding of SVA in the semen of 2 boars, and persistence of SVA within the tonsils and testes of 3 adult boars. Two SVA-infected boars that were identified on a Minnesota sow farm in 2017 shed S ...
DOI:
10.1177/10406387221084054

8. Previous biological therapy and impairment of the IFN-γ/IL-10 axis are associated with low immune response to 17DD-YF vaccination in patients with spondyloarthritis

Author:
Thays Zanon Casagrande; Ismael Artur da Costa-Rocha; Maria Bernadete Renoldi de Oliveira Gavi; Samira Tatiyama Miyamoto; Priscila Costa Martins; Érica Vieira Serrano; Valquiria Garcia Dinis; Ketty Lysie Libardi Lira Machado; Sonia Alves Gouvea; Larissa Carvalho Caser; Ana Carolina Campi-Azevedo; Andréa Teixeira-Carvalho; Vanessa Peruhype-Magalhães; Maria de Fatima Bissoli; Maria da Penha Gomes Gouvea; Sheila Maria Barbosa de Lima; Emily Hime Miranda; Gisela Freitas Trindade; Danielle Grillo Pacheco Lyra; Ana Paula Neves Burian; Lauro Ferreira da Silva Pinto Neto; Licia Maria Henrique da Mota; Olindo Assis Martins-Filho; Valéria Valim
Source:
Vaccine 2022 v.40 no.32 pp. 4580-4593
ISSN:
0264-410X
Subject:
viremia,   etc   ; adults; biomarkers; blood serum; chemokines; immune response; immunogenicity; prospective studies; seroconversion; seroprevalence; vaccination; vaccines; yellow fever;     Show all 13 Subjects
Abstract:
... Yellow fever (YF) vaccination is known to induce a suboptimal response in patients with autoimmune diseases (AIDs). To date, few studies have focused on the performance of 17DD-YF vaccination in patients with spondyloarthritis (SpA). In general, patients with SpA are young and have less comorbidities than other patients with AIDs, and frequently receive biological disease-modifying antirheumatic d ...
DOI:
10.1016/j.vaccine.2022.05.071

9. Plasma Torquetenovirus (TTV) microRNAs and severity of COVID-19

Author:
Maria Alfreda Stincarelli; Andreina Baj; Bernardo Guidotti; Pietro Giorgio Spezia; Federica Novazzi; Ersilia Lucenteforte; Silvia Tillati; Daniele Focosi; Fabrizio Maggi; Simone Giannecchini
Source:
Virology journal 2022 v.19 no.1 pp. 79
ISSN:
1743-422X
Subject:
viremia,   etc   ; Anelloviridae; COVID-19 infection; DNA; Severe acute respiratory syndrome coronavirus 2; humans; immune evasion; immunocompetence; microRNA; virology;     Show all 10 Subjects
Abstract:
... BACKGROUND: Torquetenovirus (TTV), a widespread anellovirus recognized as the main component of the healthy human virome, displays viremia that is highly susceptible to variations in immune competence. TTV possesses microRNA (miRNA)-coding sequences that might be involved in viral immune evasion. Among TTV-encoded miRNAs, miRNA t1a, t3b, and tth8 have been found in biological fluids. Here, the pre ...
DOI:
10.1186/s12985-022-01812-3

10. Pathogenicity of Porcine Circovirus Type 2e in Experimentally Infected Pigs

Author:
Taehwan Oh; Jeongmin Suh; Chanhee Chae
Source:
Journal of comparative pathology 2022 v.195 pp. 19-27
ISSN:
0021-9975
Subject:
viremia,   etc   ; Mycoplasma hyopneumoniae; Porcine circovirus; blood; genotype; lymph; mixed infection; pathogenicity; pathogens; porcine reproductive and respiratory syndrome; swine; viruses;     Show all 12 Subjects
Abstract:
... A new porcine circovirus type 2e (PCV2e) genotype was recently isolated from diseased pigs. To investigate the pathogenicity of PCV2e, groups of conventional pigs were inoculated in one of three ways: with PCV2e only, with Mycoplasma hyopneumoniae and PCV2e, or with PCV2e and porcine reproductive and respiratory syndrome virus (PRRSV). Pigs were examined post mortem at 21 days post inoculation. Pi ...
DOI:
10.1016/j.jcpa.2022.05.001

11. Distribution of equine coronavirus RNA in the intestinal and respiratory tracts of experimentally infected horses

Author:
Yoshinori Kambayashi; Daiki Kishi; Takanori Ueno; Minoru Ohta; Hiroshi Bannai; Koji Tsujimura; Yuta Kinoshita; Manabu Nemoto
Source:
Archives of virology 2022 v.167 no.8 pp. 1611-1618
ISSN:
0304-8608
Subject:
viremia,   etc   ; Orthocoronavirinae; RNA; anorexia; diarrhea; feces; fever; horses; hybridization; intestines; lungs; nose; reverse transcriptase polymerase chain reaction; virology; viruses;     Show all 15 Subjects
Abstract:
... Equine coronavirus (ECoV) causes pyrexia, anorexia, lethargy, and sometimes diarrhoea. Infected horses excrete the virus in their faeces, and ECoV is also detected in nasal samples from febrile horses. However, details about ECoV infection sites in the intestinal and respiratory tracts are lacking. To identify the ECoV infection sites in the intestinal and respiratory tracts, we performed an exper ...
DOI:
10.1007/s00705-022-05488-6

12. SARS-CoV-2, Placental Histopathology, Gravity of Infection and Immunopathology: Is There an Association?

Author:
Leonardo Resta; Antonella Vimercati; Gerardo Cazzato; Margherita Fanelli; Sara Vincenza Scarcella; Giuseppe Ingravallo; Anna Colagrande; Sara Sablone; Mary Stolfa; Francesca Arezzo; Teresa Lettini; Roberta Rossi
Source:
Viruses 2022 v.14 no.6 pp. -
ISSN:
1999-4915
Subject:
viremia,   etc   ; Severe acute respiratory syndrome coronavirus 2; blood vessels; gravity; histopathology; immunohistochemistry; immunopathology; macrophages; pandemic; placenta; premature birth; thrombosis;     Show all 12 Subjects
Abstract:
... (1) Background: As the pandemic months progress, more and more evidence shows that the placenta acts as a “barrier” to SARS-CoV-2, although rare cases of vertical transmission have been described. (2) Methods: In an attempt to investigate whether the symptoms’ severity was related to different placental histological characteristics and the immune microenvironment, we subdivided 29 placentas from 2 ...
DOI:
10.3390/v14061330

13. Development of a Singleplex Real-Time Reverse Transcriptase PCR Assay for Pan-Dengue Virus Detection and Quantification

Author:
Adisak Songjaeng; Somchai Thiemmeca; Dumrong Mairiang; Nuntaya Punyadee; Kessiri Kongmanas; Prachya Hansuealueang; Nattaya Tangthawornchaikul; Thaneeya Duangchinda; Juthathip Mongkolsapaya; Kanokwan Sriruksa; Wannee Limpitikul; Prida Malasit; Panisadee Avirutnan
Source:
Viruses 2022 v.14 no.6 pp. -
ISSN:
1999-4915
Subject:
viremia,   etc   ; Dengue virus; RNA; cross reaction; decline; early diagnosis; patients; reverse transcriptase polymerase chain reaction; serotypes; therapeutics; viral genome; viruses;     Show all 12 Subjects
Abstract:
... Dengue virus (DENV) infection is a significant global health problem. There are no specific therapeutics or widely available vaccines. Early diagnosis is critical for patient management. Viral RNA detection by multiplex RT-PCR using multiple pairs of primers/probes allowing the simultaneous detection of all four DENV serotypes is commonly used. However, increasing the number of primers in the RT-P ...
DOI:
10.3390/v14061271

14. Susceptibility of common family Anatidae bird species to clade 2.3.4.4e H5N6 high pathogenicity avian influenza virus: an experimental infection study

Author:
Kosuke Soda; Yukiko Tomioka; Chiharu Hidaka; Mayu Matsushita; Tatsufumi Usui; Tsuyoshi Yamaguchi
Source:
BMC veterinary research 2022 v.18 no.1 pp. 127
ISSN:
1746-6148
Subject:
viremia,   etc   ; Anas acuta; Anas penelope; Influenza A virus; Japan; avian influenza; cloaca; ducks; eggs; pancreas; pathogenicity; veterinary medicine; viruses; winter;     Show all 14 Subjects
Abstract:
... BACKGROUND: There were large outbreaks of high pathogenicity avian influenza (HPAI) caused by clade 2.3.4.4e H5N6 viruses in the winter of 2016–2017 in Japan, which caused large numbers of deaths among several endangered bird species including cranes, raptors, and birds in Family Anatidae. In this study, susceptibility of common Anatidae to a clade 2.3.4.4e H5N6 HPAI virus was assessed to evaluate ...
DOI:
10.1186/s12917-022-03222-7

15. Polyomavirus BK Genome Comparison Shows High Genetic Diversity in Kidney Transplant Recipients Three Months after Transplantation

Author:
Olga Mineeva-Sangwo; Joan Martí-Carreras; Evert Cleenders; Dirk Kuypers; Piet Maes; Graciela Andrei; Maarten Naesens; Robert Snoeck
Source:
Viruses 2022 v.14 no.7 pp. -
ISSN:
1999-4915
Subject:
viremia,   etc   ; DNA; Human polyomavirus 1; amino acids; genetic variation; genome; humans; kidney diseases; kidney transplant; kidneys; pathogenicity; risk; viral load;     Show all 13 Subjects
Abstract:
... BK polyomavirus (BKPyV) is a human DNA virus generally divided into twelve subgroups based on the genetic diversity of Viral Protein 1 (VP1). BKPyV can cause polyomavirus-associated nephropathy (PVAN) after kidney transplantation. Detection of BKPyV DNA in blood (viremia) is a source of concern and increase in plasma viral load is associated with a higher risk of developing PVAN. In this work, we ...
DOI:
10.3390/v14071533

16. Analysis of HIV quasispecies and virological outcome of an HIV D+/R+ kidney–liver transplantation

Author:
Gabriella Rozera; Ubaldo Visco-Comandini; Emanuela Giombini; Francesco Santini; Federica Forbici; Giulia Berno; Cesare Gruber; Paolo De Paolis; Roberto Colonnelli; Gianpiero D’Offizi; Giuseppe Maria Ettorre; Paolo Grossi; Maria Rosaria Capobianchi; Giuseppe Ippolito; Isabella Abbate
Source:
Virology journal 2022 v.19 no.1 pp. 4
ISSN:
1743-422X
Subject:
viremia,   etc   ; CD4-positive T-lymphocytes; DNA; RNA; drug resistance; evolution; genetic heterogeneity; genotype; genotyping; immunosuppression; kidneys; liver; superinfection; therapeutics; virology; women;     Show all 16 Subjects
Abstract:
... INTRODUCTION: Transplantation among HIV positive patients may be a valuable therapeutic intervention. This study involves an HIV D+/R+ kidney–liver transplantation, where PBMC-associated HIV quasispecies were analyzed in donor and transplant recipients (TR) prior to transplantation and thereafter, together with standard viral monitoring. METHODS: The donor was a 54 year of age HIV infected woman: ...
DOI:
10.1186/s12985-021-01730-w

17. Molecular characteristics and pathogenicity of an equid alphaherpesvirus 1 strain isolated in China

Author:
Yue Hu; Qinrui Jia; Jianhua Liu; Wencheng Sun; Zilei Bao; Chuanzhong Che; Guiling Wu; Bin Fan; Jarhen; Duoliang Ran
Source:
Virus genes 2022 v.58 no.4 pp. 284-293
ISSN:
0920-8569
Subject:
viremia,   etc   ; Equid alphaherpesvirus 1; amino acids; fetus; genotype; hindlimbs; horses; industry; lameness; lungs; nucleotide sequences; pathogenicity; phylogeny; viruses; China; United Kingdom;     Show all 16 Subjects
Abstract:
... Equid alphaherpesvirus 1 (EHV-1) is prevalent in China, and causes notable economic damage to the equine industry. However, there is no information regarding the molecular characteristics and pathogenicity of the Chinese strains. Therefore, an EHV-1 strain, named YM2019, was isolated from the lung tissue of an aborted horse fetus in Xinjiang, China, and its genome and pathogenicity were analyzed. ...
DOI:
10.1007/s11262-022-01910-y

18. Minor and major envelope proteins of PRRSV play synergistic roles in inducing heterologous neutralizing antibodies and conferring cross protection

Author:
Jixiang Li; Shubin Li; Ming Qiu; Xinshuai Li; Chen Li; Binghui Feng; Hong Lin; Wanglong Zheng; Jianzhong Zhu; Nanhua Chen
Source:
Virus research 2022 v.315 pp. 198789
ISSN:
0168-1702
Subject:
viremia,   etc   ; Betaarterivirus suid 2; consensus sequence; cross immunity; fever; genetic variation; immunization; lungs; porcine reproductive and respiratory syndrome; research; virulence; viruses;     Show all 12 Subjects
Abstract:
... High genetic diversity of porcine reproductive and respiratory syndrome virus (PRRSV) isolates is a major obstacle for the development of effective PRRS vaccines. A chimeric highly pathogenic PRRSV2 (HP-PRRSV2) strain containing the consensus sequence of ORF2-6 genes was constructed in our previous study, which could induce broadly neutralizing antibodies (bnAbs) and confer satisfied cross protect ...
DOI:
10.1016/j.virusres.2022.198789

19. Essential oil nebulization in mild COVID-19(EONCO): Early phase exploratory clinical trial

Author:
Ramya Rathod; Ritin Mohindra; Akshay Vijayakumar; Roop Kishor Soni; Ramandeep Kaur; Ankit Kumar; Naveen Hegde; Aishwarya anand; Swati Sharma; Vikas Suri; Kapil goyal; Arnab Ghosh; Ashish Bhalla; Nanda Gamad; Amritpal Singh; Amol N. Patil
Source:
Journal of Ayurveda and integrative medicine 2022 pp. 100626
ISSN:
0975-9476
Subject:
viremia,   etc   ; Ayurvedic medicine; COVID-19 infection; antiviral properties; atomization; clinical trials; essential oils; placebos; reverse transcriptase polymerase chain reaction; taste disorders; therapeutics;     Show all 11 Subjects
Abstract:
... Medications studied for therapeutic benefits in coronavirus disease 2019 (COVID-19) have produced inconclusive efficacy results except for steroids. A prospective randomized open-label, parallel-arm Phase I/II clinical trial was planned to compare essential oil (EO) blend versus placebo nebulization in mild COVID-19. A Phase I safety evaluation was carried out in a single ascending and multiple as ...
DOI:
10.1016/j.jaim.2022.100626

20. Changes in serum cardiac troponin i in asian elephants (elephas maximus) with elephant endotheliotropic herpesvirus infection

Author:
Kailey B. Anderson; James C. Steeil; Erin Latimer; Victoria Hall; Lee-Ann C. Hayek; João Brandão
Source:
Journal of zoo and wildlife medicine 2022 v.53 no.2 pp. 249-258
ISSN:
1937-2825
Subject:
viremia,   etc   ; Elephantid betaherpesvirus 1; Elephas maximus; Herpesviridae infections; blood serum; cardiomyocytes; death; hemorrhage; medicine; mortality; quantitative polymerase chain reaction; troponin I; wildlife; zoos;     Show all 14 Subjects
Abstract:
... Elephant endotheliotropic herpesvirus (EEHV) is one of the most important causes of mortality in Asian elephants (Elephas maximus). The unusual tropism of EEHV for endothelial cells of capillaries can lead to catastrophic vascular dysfunction, hemorrhage, cardiac damage, and death. Cardiac troponin I (cTnI) is an intracellular protein of cardiomyocytes that is released into circulation in levels d ...
DOI:
10.1638/2021-0003