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1. Comparison of 4 commercial modified-live porcine reproductive and respiratory syndrome virus (PRRSV) vaccines against heterologous Korean PRRSV-1 and PRRSV-2 challenge

Author:
Oh, T.; Kim, H.; Park, K. H.; Yang, S.; Jeong, J.; Kim, S.; Kang, I.; Park, S. J.; Chae, C.
Source:
Canadian journal of veterinary research 2019 v.83 no.1 pp. 57-67
ISSN:
0830-9000
Subject:
viremia,   etc   ; Porcine reproductive and respiratory syndrome virus; lungs; swine; vaccination; vaccines; virology;     Show all 7 Subjects
Abstract:
... The efficacy of 4 commercial porcine reproductive and respiratory syndrome virus (PRRSV) modified-live vaccines (MLV), against PRRSV-1 and PRRSV-2 was evaluated and compared in growing pigs. Two of the vaccines were based on PRRSV-1 and two on PRRSV-2. There were no significant differences between each of the two PRRSV-1 MLV vaccines and the two PRRSV-2 MLV vaccines respectively based on virology, ...

2. Possible pathogenicity of Japanese encephalitis virus in newly hatched domestic ducklings

Author:
Xiao, Changguang; Wang, Xin; Cui, Guanghui; Pang, Linlin; Xu, Jinpeng; Li, Chenxi; Zhang, Junjie; Liu, Ke; Li, Beibei; Shao, Donghua; Qiu, Yafeng; Wei, Jianchao; Ma, Zhiyong
Source:
Veterinary microbiology 2018 v.227 pp. 8-11
ISSN:
0378-1135
Subject:
viremia,   etc   ; Culicidae; Japanese encephalitis virus; ducklings; hosts; mortality; pathogenicity;     Show all 7 Subjects
Abstract:
... Japanese encephalitis virus (JEV) is a zoonotic flavivirus that is transmitted by mosquitoes and vertebrate-amplifying hosts, including birds. Domestic ducks are susceptible to JEV infection and develop various levels of viremia. We tested the pathogenicities of seven JEV strains in newly hatched domestic ducklings. All inoculated ducklings showed stunted growth. Two JEV strains caused notable mor ...
DOI:
10.1016/j.vetmic.2018.10.016

3. Linking Bird and Mosquito Data to Assess Spatiotemporal West Nile Virus Risk in Humans

Author:
Talbot, Benoit; Caron-Lévesque, Merlin; Ardis, Mark; Kryuchkov, Roman; Kulkarni, Manisha A.
Source:
EcoHealth 2019 v.16 no.1 pp. 70-81
ISSN:
1612-9202
Subject:
viremia,   etc   ; Aedes; Culex; Ochlerotatus; West Nile virus; birds; hematophagy; host preferences; hosts; humans; insect vectors; risk; viruses; Canada;     Show all 14 Subjects
Abstract:
... West Nile virus (WNV; family Flaviviridae) causes a disease in humans that may develop into a deadly neuroinvasive disease. In North America, several peridomestic bird species can develop sufficient viremia to infect blood-feeding mosquito vectors without succumbing to the virus. Mosquito species from the genus Culex, Aedes and Ochlerotatus display variable host preferences, ranging between birds ...
DOI:
10.1007/s10393-019-01393-8

4. Equine hepacivirus persistent infection in a horse with chronic wasting

Author:
Elia, G.; Lanave, G.; Lorusso, E.; Parisi, A.; Trotta, A.; Buono, R.; Martella, V.; Decaro, N.; Buonavoglia, C.
Source:
Transboundary and emerging diseases 2017 v.64 no.5 pp. 1354-1358
ISSN:
1865-1674
Subject:
viremia,   etc   ; Hepatitis C virus; chronic diseases; horses;     Show all 4 Subjects
Abstract:
... Equine hepacivirus is the closest homologue of hepatitis C virus. Limited data on the clinical features of this infection are available. We report the identification of a horse with high‐titre viremia by equine hepacivirus. Over a 15‐month follow‐up, the clinical signs and the viremic status persisted, suggesting a chronic evolution. ...
DOI:
10.1111/tbed.12679

5. Effect of freeze-dried Carica papaya leaf juice on inflammatory cytokines production during dengue virus infection in AG129 mice

Author:
Norahmad, Nor Azrina; Mohd Abd Razak, Mohd Ridzuan; Mohmad Misnan, Norazlan; Md Jelas, Nur Hana; Sastu, Umi Rubiah; Muhammad, Amirrudin; Ho, Tiffiny Chau Dee; Jusoh, Bazilah; Zolkifli, Nor Azlina; Thayan, Ravindran; Mat Ripen, Adiratna; Zainol, Murizal; Syed Mohamed, Ami Fazlin
Source:
BMC complementary and alternative medicine 2019 v.19 no.1 pp. 44
ISSN:
1472-6882
Subject:
viremia,   etc   ; Carica papaya; Dengue virus; alternative medicine; cytokines; dengue; disease models; freeze drying; gene expression; gene expression regulation; genes; immunoassays; immunomodulators; juices; leaves; liver; mice; polymerase chain reaction;     Show all 18 Subjects
Abstract:
... BACKGROUND: Carica papaya leaves have been used for traditional treatment of dengue fever and have been reported to exhibit an immunomodulatory activity by affecting the level of cytokine production in vitro and in vivo. Due to the lack of adequate in vivo evidence in dengue disease model, the present study was initiated to screen and identify the cytokines affected by freeze-dried C. papaya leaf ...
DOI:
10.1186/s12906-019-2438-3

6. Maternally-derived neutralizing antibodies reduce vaccine efficacy against porcine reproductive and respiratory syndrome virus infection

Author:
Renson, Patricia; Fablet, Christelle; Andraud, Mathieu; Normand, Valérie; Lebret, Arnaud; Paboeuf, Frédéric; Rose, Nicolas; Bourry, Olivier
Source:
Vaccine 2019 v.37 no.31 pp. 4318-4324
ISSN:
0264-410X
Subject:
viremia,   etc   ; Porcine reproductive and respiratory syndrome virus; herds; neutralizing antibodies; piglets; porcine reproductive and respiratory syndrome; vaccination; vaccines; virus transmission; viruses;     Show all 10 Subjects
Abstract:
... Modified live virus (MLV) vaccines are commonly used to reduce the impact of porcine reproductive and respiratory syndrome (PRRS) but limited efficacy is achieved in field conditions. Here, we evaluated the impact of maternally-derived neutralizing antibodies (MDNAs) on vaccine efficacy after PRRS virus (PRRSV) challenge. Piglets with low (A−) or high (A+) MDNA levels derived from a commercial pig ...
DOI:
10.1016/j.vaccine.2019.06.045

7. Evidence of reduced viremia, pathogenicity and vector competence in a re‐emerging European strain of bluetongue virus serotype 8 in sheep

Author:
Flannery, John; Sanz‐Bernardo, Beatriz; Ashby, Martin; Brown, Hannah; Carpenter, Simon; Cooke, Lyndsay; Corla, Amanda; Frost, Lorraine; Gubbins, Simon; Hicks, Hayley; Qureshi, Mehnaz; Rajko‐Nenow, Paulina; Sanders, Christopher; Tully, Matthew; Bréard, Emmanuel; Sailleau, Corinne; Zientara, Stephan; Darpel, Karin; Batten, Carrie
Source:
Transboundary and emerging diseases 2019 v.66 no.3 pp. 1177-1185
ISSN:
1865-1674
Subject:
viremia,   etc   ; Bluetongue virus; Culicoides sonorensis; RNA; antibodies; emerging diseases; genome; lameness; livestock and meat industry; pathogenicity; serotypes; sheep; vector competence; viruses; France; United Kingdom;     Show all 16 Subjects
Abstract:
... The outbreak of bluetongue virus (BTV) serotype 8 (BTV‐8) during 2006–2009 in Europe was the most costly epidemic of the virus in recorded history. In 2015, a BTV‐8 strain re‐emerged in France which has continued to circulate since then. To examine anecdotal reports of reduced pathogenicity and transmission efficiency, we investigated the infection kinetics of a 2007 UK BTV‐8 strain alongside the ...
DOI:
10.1111/tbed.13131

8. A comparative study of the efficacy of a porcine reproductive and respiratory syndrome subunit and a modified-live virus vaccine against respiratory diseases in endemic farms

Author:
Oh, T.; Kim, H.; Park, K. H.; Jeong, J.; Yang, S.; Kang, I.; Park, S. J.; Chae, C.
Source:
Canadian journal of veterinary research 2019 v.83 no.2 pp. 110-121
ISSN:
0830-9000
Subject:
viremia,   etc   ; T-lymphocytes; farms; growth performance; mixed infection; neutralization; neutralizing antibodies; porcine reproductive and respiratory syndrome; respiratory tract diseases; subunit vaccines; swine; vaccination; veterinary medicine; viruses;     Show all 14 Subjects
Abstract:
... The efficacy of a porcine reproductive and respiratory syndrome (PRRS) subunit vaccine was evaluated and compared with a modified-live virus (MLV) vaccine under field conditions. Three farms were selected based on their history of respiratory diseases caused by co-infection with both PRRSV-1 and PRRSV-2. In each farm, 60 pigs were randomly allocated to 2 vaccinated and 1 unvaccinated groups (20 pi ...

9. Comparison of four commercial PRRSV MLV vaccines in herds with co-circulation of PRRSV-1 and PRRSV-2

Author:
Oh, Taehwan; Kim, Hanjin; Park, Kee Hwan; Jeong, Jiwoon; Yang, Siyeon; Kang, Ikjae; Chae, Chanhee
Source:
Comparative immunology, microbiology, and infectious diseases 2019 v.63 pp. 66-73
ISSN:
0147-9571
Subject:
viremia,   etc   ; Porcine reproductive and respiratory syndrome virus; farms; herds; livestock and meat industry; mixed infection; respiratory tract diseases; swine; vaccination; vaccines; viruses;     Show all 11 Subjects
Abstract:
... The efficacy of four commercial porcine reproductive and respiratory syndrome virus (PRRSV) modified-live virus (MLV) vaccines against respiratory disease was evaluated and compared in pig farms suffering from co-infection with PRRSV-1 and PRRSV-2. All vaccinated groups on average exhibited improved growth rate compared to the unvaccinated pigs. Interestingly, the two groups vaccinated with either ...
DOI:
10.1016/j.cimid.2018.12.010

10. Experimental infection of rabbit with swine-derived hepatitis E virus genotype 4

Author:
Liu, Baoyuan; Chen, Yiyang; Sun, Yani; Nan, Yuchen; Li, Huixia; Du, Taofeng; Hiscox, Julian A.; Zhao, Qin; Zhou, En-Min
Source:
Veterinary microbiology 2019 v.229 pp. 168-175
ISSN:
0378-1135
Subject:
viremia,   etc   ; Avian hepatitis E virus; Hepatitis E virus; RNA; alanine transaminase; animal models; diarrhea; genotype; liver; pathogenicity; rabbits; seroconversion; spleen; swine; virus replication; viruses; China;     Show all 17 Subjects
Abstract:
... Hepatitis E virus (HEV) is a zoonotic virus that is capable of causing cross-species infection. Rabbits can be experimentally infected with human- and swine-derived HEV-4 in the species Orthohepevirus A, and avian-derived HEV-3 in the species Orthohepevirus B suggesting rabbits can serve as an animal model for zoonotic HEV infection study. However, these studies show that the infectivity of swine ...
DOI:
10.1016/j.vetmic.2019.01.001

11. Serum Concentrations of Vascular Endothelial Growth Factor, Stromal Cell-Derived Factor, Nitric Oxide and Endothelial DNA Proliferation in Development of Microvascular Pathology in Acute African Swine Fever

Author:
Tatoyan, M.R.; Ter-Pogossyan, Z.R.; Semerjyan, A.B.; Gevorgyan, V.S.; Karalyan, N. Yu; Sahakyan, C.T.; Mkrtchyan, G.L.; Gazaryan, H.K.; Avagyan, H.R.; Karalyan, Z.A.
Source:
Journal of comparative pathology 2019 v.167 pp. 50-59
ISSN:
0021-9975
Subject:
viremia,   etc   ; African swine fever; DNA; blood cells; blood serum; cell cycle; chemokine CXCL12; endothelial cells; hemorrhage; macrophages; nitric oxide; permeability; tissues; vascular endothelial growth factors; viruses;     Show all 15 Subjects
Abstract:
... There is significant evidence that pathology of the microcirculation occurs in African swine fever (ASF); however, the mechanisms by which it develops are largely unknown. In the present experimental infection study, we show that an increase in vascular permeability in the initial stages of acute ASF is dependent on viraemia and elevation of the concentration of serum nitric oxide (NO). Macrophage ...
DOI:
10.1016/j.jcpa.2018.12.004

12. Survival of African swine fever virus (ASFV) in various traditional Italian dry-cured meat products

Author:
Petrini, Stefano; Feliziani, Francesco; Casciari, Cristina; Giammarioli, Monica; Torresi, Claudia; De Mia, Gian Mario
Source:
Preventive veterinary medicine 2019 v.162 pp. 126-130
ISSN:
0167-5877
Subject:
viremia,   etc   ; African swine fever; African swine fever virus; cured meats; exports; in vivo studies; industry; loins (meat cut); planning; pork bellies; risk; salami; swine; viral load; viruses; Italy;     Show all 16 Subjects
Abstract:
... A number of animal diseases can be transmitted to pigs via pork meat and pork products imported from infected areas. Therefore, feeding of swill to pigs is regulated or prohibited in many swine-rearing countries. African swine fever is one of the major porcine diseases recognized as significant in this transmission pathway. Assessment of disease risks associated with pork products requires knowled ...
DOI:
10.1016/j.prevetmed.2018.11.013

13. Dual Immunity Concomitantly Suppresses HIV-1 Progression

Author:
Qureshi, Huma; Bhattacharya, Jayanta
Source:
Trends in microbiology 2017 v.25 no.5 pp. 334-335
ISSN:
0966-842X
Subject:
viremia,   etc   ; Human immunodeficiency virus 1; T-lymphocytes; immunity; neutralizing antibodies;     Show all 5 Subjects
Abstract:
... Broadly neutralizing antibodies (bnAbs) elicited in HIV-1⁺ elite neutralizers typically are unable to reduce viremia in the same individuals from whom they are isolated. A recent study reports the development of bnAbs in an elite controller that, along with the help of T cells, were associated with restricting HIV-1 progression. ...
DOI:
10.1016/j.tim.2017.02.011

14. Efficacy of different DNA and MVA prime-boost vaccination regimens against a Rift Valley fever virus (RVFV) challenge in sheep 12 weeks following vaccination

Author:
Lorenzo, Gema; López-Gil, Elena; Ortego, Javier; Brun, Alejandro
Source:
Veterinary research 2018 v.49 no.1 pp. 21
ISSN:
1297-9716
Subject:
viremia,   etc   ; DNA; Rift Valley fever virus; adults; animal models; glycoproteins; immune response; neutralizing antibodies; sheep; vaccination; vaccines; veterinary medicine;     Show all 12 Subjects
Abstract:
... The aim of this work was to evaluate the immunogenicity and efficacy of DNA and MVA vaccines encoding the RVFV glycoproteins Gn and Gc in an ovine model of RVFV infection. Adult sheep of both sexes were challenged 12 weeks after the last immunization and clinical, virological, biochemical and immunological consequences, were analyzed. Strategies based on immunization with homologous DNA or heterol ...
DOI:
10.1186/s13567-018-0516-z
PubMed:
29467018
PubMed Central:
PMC5822472

15. Cross-species infection of mice by rabbit hepatitis E virus

Author:
Sun, Yani; Lu, Qizhong; Liu, Baoyuan; Sheng, Yamin; Du, Taofeng; Hiscox, Julian A.; Zhou, En-Min; Zhao, Qin
Source:
Veterinary microbiology 2018 v.225 pp. 48-52
ISSN:
0378-1135
Subject:
viremia,   etc   ; Hepatitis E virus; antibodies; blood serum; humans; liver; mice; necrosis; pathogenesis; rabbits; seroconversion; swine; viral shedding;     Show all 13 Subjects
Abstract:
... Rabbits are recognized as a zoonotic reservoir of hepatitis E virus (HEV) for transmission to humans and other zoonotic reservoirs such as swine. The purpose of this study was to assess the ability of rabbit HEV to cross the species barrier to infect mice and also the usefulness of this animal to study HEV transmission and pathogenesis. In this study, uninfected BALB/c mice were experimentally ino ...
DOI:
10.1016/j.vetmic.2018.09.015

16. A modified‐live porcine reproductive and respiratory syndrome virus (PRRSV)‐1 vaccine protects late‐term pregnancy gilts against heterologous PRRSV‐1 but not PRRSV‐2 challenge

Author:
Jeong, J.; Kang, I.; Kim, S.; Park, S.‐J.; Park, K. H.; Oh, T.; Yang, S.; Chae, C.
Source:
Transboundary and emerging diseases 2018 v.65 no.5 pp. 1227-1234
ISSN:
1865-1674
Subject:
viremia,   etc   ; Porcine reproductive and respiratory syndrome virus; breeding; emerging diseases; gestation period; gilts; piglets; pregnancy; reproductive performance; vaccination; vaccines; viruses;     Show all 12 Subjects
Abstract:
... The objective of this study was to determine the efficacy of a commercially available porcine reproductive and respiratory syndrome virus (PRRSV)‐1 modified‐live virus (MLV) vaccine against PRRSV‐1 and PRRSV‐2 challenge in late‐term pregnancy gilts. Gilts were vaccinated with the PRRSV‐1 MLV vaccine at 4 weeks prior to breeding and then challenged intranasally with PRRSV‐1 or PRRSV‐2 at 93 days of ...
DOI:
10.1111/tbed.12862

17. Time spent with residual viraemia after virological suppression below 50 HIV-RNA copies/mL according to type of first-line antiretroviral regimen

Author:
Gianotti, Nicola; Galli, Laura; Galizzi, Nadia; Ripa, Marco; Andolina, Andrea; Nozza, Silvia; Spagnuolo, Vincenzo; Poli, Andrea; Lazzarin, Adriano; Castagna, Antonella
Source:
International journal of antimicrobial agents 2018
ISSN:
0924-8579
Subject:
viremia,   etc   ; HIV infections; RNA-directed DNA polymerase; antiretroviral agents; cohort studies; drugs; patients; polymerase chain reaction; proteinase inhibitors; therapeutics;     Show all 10 Subjects
Abstract:
... To investigate if the regimen used when starting antiretroviral therapy (ART) affects the time spent with residual viraemia (RV) after achieving <50 HIV-RNA copies/mL.Retrospective cohort study on patients infected with human immunodeficiency virus (HIV), followed prospectively, who started ART with a boosted protease inhibitor (PI/r)-, a non-nucleoside reverse transcriptase inhibitor (NNRTI)- or ...
DOI:
10.1016/j.ijantimicag.2018.07.001

18. Field data implicating Culicoides stellifer and Culicoides venustus (Diptera: Ceratopogonidae) as vectors of epizootic hemorrhagic disease virus

Author:
McGregor, Bethany L.; Sloyer, Kristin E.; Sayler, Katherine A.; Goodfriend, Olivia; Krauer, Juan M. Campos; Acevedo, Carolina; Zhang, Xinmi; Mathias, Derrick; Wisely, Samantha M.; Burkett-Cadena, Nathan D.
Source:
Parasites & vectors 2019 v.12 no.1 pp. 258
ISSN:
1756-3305
Subject:
viremia,   etc   ; Cervus dama; Culicoides sonorensis; Epizootic hemorrhagic disease virus; Odocoileus virginianus; RNA; World Health Organization; blood meal; deer; elks; epizootic diseases; farms; hosts; midges; mixed infection; serotypes; virus transmission; Alabama; Florida;     Show all 19 Subjects
Abstract:
... BACKGROUND: Epizootic hemorrhagic disease virus (EHDV) is an Orbivirus of veterinary importance which is transmitted by biting midges of the genus Culicoides (Diptera: Ceratopogonidae) to ruminants. Culicoides sonorensis Wirth & Jones, the only confirmed vector of EHDV in the USA, is rare in the southeastern states where transmission persists, suggesting that other Culicoides species transmit EHDV ...
DOI:
10.1186/s13071-019-3514-8

19. The novel caprine parainfluenza virus type 3 showed pathogenicity in Guinea pigs

Author:
Hao, Fei; Wang, Zhongyu; Mao, Li; Yang, Leilei; Zhang, Wenwen; Li, Jizong; Wang, Xuyuan; Li, Wenliang; Jiang, Jieyuan
Source:
Microbial pathogenesis 2019 v.134 pp. 103569
ISSN:
0882-4010
Subject:
viremia,   etc   ; animal models; dead animals; goats; guinea pigs; hemagglutination; immunohistochemistry; laboratory animals; lungs; macrophages; necropsy; neutralizing antibodies; pathogenicity; pulmonary emphysema; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; signs and symptoms (animals and humans); staining; viral load; viruses;     Show all 20 Subjects
Abstract:
... Caprine parainfluenza virus type 3 (CPIV3) is one of the important viral respiratory tract agents in goats. The pathogenicity of CPIV3 has been examined in goats but it has not been explored in other laboratory animals. In the present study, an experimental infection of guinea pigs with CPIV3 was performed. The virus-inoculated guinea pigs displayed clinical signs related to the respiratory diseas ...
DOI:
10.1016/j.micpath.2019.103569

20. A comparably high virulence strain of porcine reproductive and respiratory syndrome virus isolated in Taiwan

Author:
Hou, Fu-Hsiang; Chia, Min-Yuan; Lee, Yi-Han; Liao, Jiunn-Wang; Lee, Wei-Cheng
Source:
Comparative immunology, microbiology, and infectious diseases 2019 v.65 pp. 96-102
ISSN:
0147-9571
Subject:
viremia,   etc   ; Porcine reproductive and respiratory syndrome virus; data collection; farms; fever; growth retardation; in vitro studies; in vivo studies; interleukin-10; monitoring; mortality; phylogeny; pneumonia; virulence; virulent strains; viruses; Taiwan;     Show all 17 Subjects
Abstract:
... Porcine reproductive and respiratory syndrome virus (PRRSV) has been endemic in Taiwan since 1991. This study aimed to present a highly virulent PRRSV in Taiwan based on farm data collection and both in vitro and in vivo evaluations in virus challenge studies. This virulent PRRSV strain was first noticed on Farm TSYM due to continuously high nursery mortality rate and severe PRRSV-associated pneum ...
DOI:
10.1016/j.cimid.2019.05.008