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1. High enrichment and near real-time quantification of airborne viruses using a wet-paper-based electrochemical immunosensor under an electrostatic field

Author:
Jyoti Bhardwaj; Nhan Dinh Ngo; Jaegil Lee; Jaesung Jang
Source:
Journal of hazardous materials 2023 v.442 pp. 130006
ISSN:
0304-3894
Subject:
virion,   etc   ; antigen-antibody reactions; electrochemistry; electrodes; electrolytes; gels; immunosensors; liquids; viruses;     Show all 9 Subjects
Abstract:
... Conventional airborne virus measurement usually requires appreciable sampling and detection times. Viral aerosols should also be collected or prepared in a liquid medium whose volume typically ranges from milliliters to tens of milliliters; hence, many sampling and detection steps need to be taken with the unit horizontal or immobile. Moreover, viral aerosols need to be sufficiently enriched, whic ...
DOI:
10.1016/j.jhazmat.2022.130006

2. Impact of needle-point bipolar ionization system in the reduction of bioaerosols in collective transport

Author:
Marta Baselga; Juan J. Alba; Alberto J. Schuhmacher
Source:
Science of the total environment 2023 v.855 pp. 158965
ISSN:
0048-9697
Subject:
virion,   etc   ; Severe acute respiratory syndrome coronavirus 2; air; bioaerosols; environment; equipment; filtration; ionization; risk;     Show all 9 Subjects
Abstract:
... The transmission rate of SARS-CoV-2 is higher in collective transport than in other public environments. Transport companies require preventive strategies to mitigate airborne risk of contagion which not imply responsible use at the individual level. Air purification systems, such as UV-C or needle-tip bipolar ionization, are attractive alternatives. However, only a few studies addressing the vali ...
DOI:
10.1016/j.scitotenv.2022.158965

3. Embedding of HIV Egress within Cortical F-Actin

Author:
Anupriya Aggarwal; Alberto Ospina Stella; Catherine C. Henry; Kedar Narayan; Stuart G. Turville
Source:
Pathogens 2022 v.11 no.1 pp. -
ISSN:
2076-0817
Subject:
virion,   etc   ; actin; genes; microfilaments; mutagenesis; proteomics;     Show all 6 Subjects
Abstract:
... F-Actin remodeling is important for the spread of HIV via cell–cell contacts; however, the mechanisms by which HIV corrupts the actin cytoskeleton are poorly understood. Through live cell imaging and focused ion beam scanning electron microscopy (FIB-SEM), we observed F-Actin structures that exhibit strong positive curvature to be enriched for HIV buds. Virion proteomics, gene silencing, and viral ...
DOI:
10.3390/pathogens11010056

4. Relationship between HIV-1 Gag Multimerization and Membrane Binding

Author:
Christopher Sumner; Akira Ono
Source:
Viruses 2022 v.14 no.3 pp. -
ISSN:
1999-4915
Subject:
virion,   etc   ; phospholipids; plasma membrane; polyproteins; virus assembly;     Show all 5 Subjects
Abstract:
... HIV-1 viral particle assembly occurs specifically at the plasma membrane and is driven primarily by the viral polyprotein Gag. Selective association of Gag with the plasma membrane is a key step in the viral assembly pathway, which is traditionally attributed to the MA domain. MA regulates specific plasma membrane binding through two primary mechanisms including: (1) specific interaction of the MA ...
DOI:
10.3390/v14030622

5. Increasing the frequency of omicron variant mutations boosts the immune response and may reduce the virus virulence

Author:
Ali Adel Dawood
Source:
Microbial pathogenesis 2022 v.164 pp. 105400
ISSN:
0882-4010
Subject:
virion,   etc   ; Orthocoronavirinae; immune response; pathogenesis; virulence; viruses; South Africa;     Show all 7 Subjects
Abstract:
... The coronavirus has posed a serious threat to the world since its discovery in Wuhan in 2019. Beta, gamma, delta, and the final omicron variants have emerged as a result of several mutations in the virion structure. The Australian Omicron S protein variant contains 37 mutations out of a total of 67 mutations. According to preliminary data from South Africa, Omicron variant infection is not associa ...
DOI:
10.1016/j.micpath.2022.105400

6. Structural Assembly of Qβ Virion and Its Diverse Forms of Virus-like Particles

Author:
Jeng-Yih Chang; Karl V. Gorzelnik; Jirapat Thongchol; Junjie Zhang
Source:
Viruses 2022 v.14 no.2 pp. -
ISSN:
1999-4915
Subject:
virion,   etc   ; Leviviridae; RNA; biotechnology; capsid; fimbriae; genomics; models; nucleotides;     Show all 9 Subjects
Abstract:
... The coat proteins (CPs) of single-stranded RNA bacteriophages (ssRNA phages) directly assemble around the genomic RNA (gRNA) to form a near-icosahedral capsid with a single maturation protein (Mat) that binds the gRNA and interacts with the retractile pilus during infection of the host. Understanding the assembly of ssRNA phages is essential for their use in biotechnology, such as RNA protection a ...
DOI:
10.3390/v14020225

7. Numerical Simulation of Airborne Disease Spread in Cage-Free Hen Housing with Multiple Ventilation Options

Author:
Long Chen; Eileen E. Fabian-Wheeler; John M. Cimbala; Daniel Hofstetter; Paul Patterson
Source:
Animals 2022 v.12 no.12 pp. -
ISSN:
2076-2615
Subject:
virion,   etc   ; air; air flow; egg industry; evolution; hens; mathematical models; viruses;     Show all 8 Subjects
Abstract:
... The current ventilation designs of poultry barns have been present deficiencies with respect to the capacity to protect against disease exposure, especially during epidemic events. An evolution of ventilation options is needed in the egg industry to keep pace with the advancing transition to cage-free production. In this study, we analyzed the performances of four ventilation schemes for constrain ...
DOI:
10.3390/ani12121516

8. Soil pH influences the structure of virus communities at local and global scales

Author:
Sungeun Lee; Jackson W. Sorensen; Robin L. Walker; Joanne B. Emerson; Graeme W. Nicol; Christina Hazard
Source:
Soil biology & biochemistry 2022 v.166 pp. 108569
ISSN:
0038-0717
Subject:
virion,   etc   ; biochemistry; community structure; microbial communities; soil biology; soil pH; viruses;     Show all 7 Subjects
Abstract:
... The influence of biotic and abiotic factors on viral communities across environmental gradients in soil is relatively unknown. While soil pH strongly influences microbial community structure, it is unclear whether there is a similar influence on soil viruses. In this study, prokaryotic and viral communities were characterized in soils from a long-term pH-manipulated soil gradient (pH 4.5 and 7.5), ...
DOI:
10.1016/j.soilbio.2022.108569

9. The Bacillus phage SPβ and its relatives: a temperate phage model system reveals new strains, species, prophage integration loci, conserved proteins and lysogeny management components

Author:
Katharina Kohm; Valentina A. Floccari; Veronika T. Lutz; Birthe Nordmann; Carolin Mittelstädt; Anja Poehlein; Anna Dragoš; Fabian M. Commichau; Robert Hertel
Source:
Environmental microbiology 2022 v.24 no.4 pp. 2098-2118
ISSN:
1462-2912
Subject:
virion,   etc   ; bacteriophages; integrases; loci; lysogeny; mutants; new species; phenotype; proteome; transcriptome;     Show all 10 Subjects
Abstract:
... The Bacillus phage SPβ has been known for about 50 years, but only a few strains are available. We isolated four new wild‐type strains of the SPbeta species. Phage vB_BsuS‐Goe14 introduces its prophage into the spoVK locus, previously not observed to be used by SPβ‐like phages. Sequence data revealed the genome replication strategy and the genome packaging mode of SPβ‐like phages. We extracted 55 ...
DOI:
10.1111/1462-2920.15964

10. New method to quantify hydrophobicity of non-enveloped virions in aqueous media by capillary zone electrophoresis

Author:
Guillaume Bastin; Christophe Gantzer; Guillaume Sautrey
Source:
Virology 2022 v.568 pp. 23-30
ISSN:
0042-6822
Subject:
virion,   etc   ; capillary zone electrophoresis; capsid; human health; hydrophobicity; pH; sodium; virology;     Show all 8 Subjects
Abstract:
... The hydrophobicity of virions is a major physicochemical parameter regulating their dissemination in humans and the environment. But knowledge about potential factors modulating virion hydrophobicity is limited due to the lack of suitable quantifying methods. It has been recently shown that sodium dodecyl-sulfate (SDS) labels capsid hydrophobic domains in capillary zone electrophoresis of non-enve ...
DOI:
10.1016/j.virol.2022.01.004

11. The Genetic Stability, Replication Kinetics and Cytopathogenicity of Recombinant Avian Coronaviruses with a T16A or an A26F Mutation within the E Protein Is Cell-Type Dependent

Author:
Isobel Webb; Sarah Keep; Kieran Littolff; Jamie Stuart; Graham Freimanis; Paul Britton; Andrew D. Davidson; Helena J. Maier; Erica Bickerton
Source:
Viruses 2022 v.14 no.8 pp. -
ISSN:
1999-4915
Subject:
virion,   etc   ; Infectious bronchitis virus; chickens; cytopathogenicity; genetic stability; ion channels; kidneys; mutation;     Show all 8 Subjects
Abstract:
... The envelope (E) protein of the avian coronavirus infectious bronchitis virus (IBV) is a small-membrane protein present in two forms during infection: a monomer and a pentameric ion channel. Each form has an independent role during replication; the monomer disrupts the secretory pathway, and the pentamer facilitates virion production. The presence of a T16A or A26F mutation within E exclusively ge ...
DOI:
10.3390/v14081784

12. Identifying bracovirus and ichnovirus genes involved in virion morphogenesis

Author:
Ange Lorenzi; Michael R Strand; Gaelen R Burke; Anne-Nathalie Volkoff
Source:
Current opinion in insect science 2022 v.49 pp. 63-70
ISSN:
2214-5745
Subject:
virion,   etc   ; Braconidae; Ichneumonidae; RNA interference; electron microscopy; genes; insects; morphogenesis; multiomics; parasitoids;     Show all 10 Subjects
Abstract:
... Bracoviruses (BVs) and ichnoviruses (IVs) evolved from different endogenized viruses but through convergence have been coopted by parasitoids in the families Braconidae and Ichneumonidae for similar functions in parasitizing hosts. Experimentally studying the role of endogenized viral genes in virion morphogenesis remains a key challenge in the study of BVs and IVs. Here we summarize how multiomic ...
DOI:
10.1016/j.cois.2021.11.006

13. Evolution of Phage Tail Sheath Protein

Author:
Peter Evseev; Mikhail Shneider; Konstantin Miroshnikov
Source:
Viruses 2022 v.14 no.6 pp. -
ISSN:
1999-4915
Subject:
virion,   etc   ; Archaea; adsorption; bacteriophages; computer software; phylogeny; type VI secretion system; viral proteins;     Show all 8 Subjects
Abstract:
... Sheath proteins comprise a part of the contractile molecular machinery present in bacteriophages with myoviral morphology, contractile injection systems, and the type VI secretion system (T6SS) found in many Gram-negative bacteria. Previous research on sheath proteins has demonstrated that they share common structural features, even though they vary in their size and primary sequence. In this stud ...
DOI:
10.3390/v14061148

14. Virus Hijacks Host Proteins and Machinery for Assembly and Budding, with HIV-1 as an Example

Author:
Chih-Yen Lin; Aspiro Nayim Urbina; Wen-Hung Wang; Arunee Thitithanyanont; Sheng-Fan Wang
Source:
Viruses 2022 v.14 no.7 pp. -
ISSN:
1999-4915
Subject:
virion,   etc   ; RNA; galectins; host-pathogen relationships; mutation; plasma membrane; polyproteins; virus assembly; viruses;     Show all 9 Subjects
Abstract:
... Viral assembly and budding are the final steps and key determinants of the virus life cycle and are regulated by virus–host interaction. Several viruses are known to use their late assembly (L) domains to hijack host machinery and cellular adaptors to be used for the requirement of virus replication. The L domains are highly conserved short sequences whose mutation or deletion may lead to the accu ...
DOI:
10.3390/v14071528

15. Pararetroviruses: Plant Infecting dsDNA Viruses

Author:
Noohi Nasim; Nrisingha Dey
Source:
Plant molecular biology reporter 2022 v.40 no.1 pp. 106-118
ISSN:
0735-9640
Subject:
virion,   etc   ; Caulimoviridae; DNA; gene expression; genome; geographical distribution; molecular biology; taxonomy; transcription (genetics); viruses;     Show all 10 Subjects
Abstract:
... Plant pararetroviruses (PRVs; family Caulimovirida) are non-enveloped double-stranded DNA viruses having either isometric or bacilliform virion. According to the current taxonomy, the family Caulimoviridae consists of ten genera with two newly added genera Dioscovirus and Vaccinivirus. PRVs have a genome size between 7 and 9 kilobase pairs and differ mainly based on the number of open reading fram ...
DOI:
10.1007/s11105-021-01294-7

16. Oseltamivir modified bovine serum albumin inhibits neuraminidase activity and accumulates virion particles to disturb influenza virus replication

Author:
Hai-Juan Qin; Shuang Li; Yu-Bo Zhu; Yan-Bin Bao; Qi Tang; Wen-Bin Liu; Ming Zhong; YueTao Zhao; Yang Yang
Source:
Carbohydrate research 2022 v.520 pp. 108631
ISSN:
0008-6215
Subject:
virion,   etc   ; Orthomyxoviridae; absorbents; bovine serum albumin; carbohydrates; chemical bonding; influenza; oseltamivir; research; sialidase; virus replication;     Show all 11 Subjects
Abstract:
... The preparation of oseltamivir-bovine serum albumin conjugate (OS-BSA) for use as a multivalent influenza neuraminidase (NA) inhibitor is reported. Briefly, the oseltamivir azidohexyl ester was synthesized and covalently bound via an orthogonal attachment to bicyclononyne-modified BSA using copper-free click chemistry. Primary antiviral assays on NA protein and cellular levels showed that the synt ...
DOI:
10.1016/j.carres.2022.108631

17. Advanced infections by cucurbit yellow stunting disorder virus encourage whitefly vector colonization while discouraging non-vector aphid competitors

Author:
Quentin Chesnais; Penglin Sun; Kerry E. Mauck
Source:
Journal of pest science 2022 v.95 no.1 pp. 231-247
ISSN:
1612-4758
Subject:
virion,   etc   ; Aphis gossypii; Bemisia tabaci; Cucumis melo; leaves; metabolites; metabolomics; muskmelons; pests; phloem; progeny; viruses;     Show all 12 Subjects
Abstract:
... Plant viruses can change hosts in ways that increase vector contacts, virion acquisition, and subsequent vector dispersal to susceptible hosts. Based on this, researchers have proposed that virus-induced phenotypes are the product of adaptations to “manipulate” hosts in ways that increase transmission. Theoretical models of virus spread in crops support this proposition; “manipulative” viruses spr ...
DOI:
10.1007/s10340-021-01394-z

18. Development of a high-throughput RT-PCR based viral infectivity assay for monitoring the stability of a replicating recombinant Lymphocytic Choriomeningitis viral vector

Author:
Vineet Gupta; Lorena R. Antunez; Soraia Saleh-Birdjandi; Ozan S. Kumru; Richard Pospisil; Anders Lilja; Gerhard Fuhrmann; Lee Smith; David B. Volkin; Sangeeta B. Joshi
Source:
Journal of virological methods 2022 v.301 pp. 114440
ISSN:
0166-0934
Subject:
virion,   etc   ; Lymphocytic choriomeningitis mammarenavirus; freeze-thaw cycles; pathogenicity; reverse transcriptase polymerase chain reaction; titration; viruses;     Show all 7 Subjects
Abstract:
... Traditional virus infectivity titration methods for lymphocytic choriomeningitis virus (LCMV) are laborious, time-consuming, and low-throughput (e.g., focus forming unit (FFA) assay). In this report, we developed a high-throughput reverse transcription quantitative PCR (RT-qPCR)-based virus infectivity assay for relative quantitation of a live, recombinant replicating LCMV -based viral vector (TT1 ...
DOI:
10.1016/j.jviromet.2021.114440

19. Potential Proteins Interactions with Bombyx mori Nucleopolyhedrovirus Revealed by Co-Immunoprecipitation

Author:
Xiong Wang; Guangyu Ma; Feifei Ren; Mian Muhammad Awais; Jingchen Sun
Source:
Insects 2022 v.13 no.7 pp. -
ISSN:
2075-4450
Subject:
virion,   etc   ; Bombyx mori nucleopolyhedrovirus; bioinformatics; gene ontology; precipitin tests; sericulture; silkworms; virulence; virus replication; viruses;     Show all 10 Subjects
Abstract:
... Virus–host interactions are critical for virus replication, virulence, and pathogenicity. The Bombyx mori nucleopolyhedrovirus (BmNPV) is a typical model baculovirus, representing one of the most common and harmful pathogens in sericulture. Herein, we used co-immunoprecipitation to identify candidate proteins with potential interactions with BmNPV. First, a recombinant BV virus particle rBmBV-egfp ...
DOI:
10.3390/insects13070575

20. Rapid high-throughput compatible label-free virus particle quantification method based on time-resolved luminescence

Author:
Kari Kopra; Nazia Hassan; Emmiliisa Vuorinen; Salla Valtonen; Randa Mahran; Huda Habib; Pinja Jalkanen; Petri Susi; Vesa Hytönen; Minna Hankaniemi; Seppo Ylä-Herttuala; Laura Kakkola; Markus Peurla; Harri Härmä
Source:
Analytical and bioanalytical chemistry 2022 v.414 no.15 pp. 4509-4518
ISSN:
1618-2642
Subject:
virion,   etc   ; analytical chemistry; bioterrorism; cost effectiveness; diagnostic techniques; genome; instrumentation; luminescence; pathogenicity; vaccine development; viruses;     Show all 11 Subjects
Abstract:
... Viruses play a major role in modern society and create risks from global pandemics and bioterrorism to challenges in agriculture. Virus infectivity assays and genome copy number determination methods are often used to obtain information on virus preparations used in diagnostics and vaccine development. However, these methods do not provide information on virus particle count. Current methods to me ...
DOI:
10.1007/s00216-022-04104-5