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1. Binding interaction and stability of alpha-lactalbumin and retinol: Effects of pre- or post-acidification

Author:
Wei Chen; Jinzhe Li; Yue Ma; Ruijie Shi; Haiying Yu; Munkh-Amgalan Gantumur; Akhunzada Bilawal; Zhanmei Jiang
Source:
Food hydrocolloids 2023 v.135 pp. 108140
ISSN:
0268-005X
Subject:
vitamin A,   etc   ; fluorescence; food matrix; hydrocolloids; hydrophobic bonding; hydrophobicity; lactalbumin; pH; storage quality; thermal degradation; thermodynamics;     Show all 11 Subjects
Abstract:
... The binding mechanisms of alpha-lactalbumin (ALa) with retinol (VA) and storage stability of their complex after pre-or post-acidification (pH 3.0) were investigated and compared by using multi-spectroscopic approaches. Fluorescence quenching results showed that combination of ALa with VA presented a typically static quenching mode at pH 3.0 with pre- or post-acidification. And the binding constan ...
DOI:
10.1016/j.foodhyd.2022.108140

2. Vitamins, minerals and heavy metals profiling of seaweeds from Mauritius and Rodrigues for food security

Author:
Devesh Bekah; Asho D. Thakoor; Avin Ramanjooloo; Itisha Chummun Phul; Sabine Botte; Prerna Roy; Preeti Oogarah; Sarvanen Curpen; Nowsheen Goonoo; John Bolton; Archana Bhaw-Luximon
Source:
Journal of food composition and analysis 2023 v.115 pp. 104909
ISSN:
0889-1575
Subject:
vitamin A,   etc   ; Udotea; X-radiation; ascorbic acid; food composition; food security; high performance liquid chromatography; macroalgae; silicon; spectroscopy; Indian Ocean; Mauritius;     Show all 12 Subjects
Abstract:
... Oceans cover more than 70 % the Earth’s surface and thus seaweeds and algae have the potential to become major sources of nutrients in the future for the expanding world population. The profiling of vitamins, minerals and heavy metals in aqueous green, red and brown seaweeds extracts from the Mascarene Islands Mauritius and Rodrigues in the Indian Ocean has been carried out for the first time. The ...
DOI:
10.1016/j.jfca.2022.104909

3. Light-induced algae retinal stress can deform fish spines

Author:
Yuelei Dong; Xiaoyu Zhou; Jianwei Zheng; Jingyi Cen; Yuzao Qi; Songhui Lu; Lei Cui
Source:
Aquaculture 2023 v.562 pp. 738758
ISSN:
0044-8486
Subject:
vitamin A,   etc   ; Artemia salina; Oryzias melastigma; Tetraselmis; Thalassiosira pseudonana; algae; algae culture; algal blooms; aquaculture industry; biomass; blue light; fish; food chain; live feeds; mariculture; metabolites; oxidoreductases; regulator genes; teratogenicity;     Show all 19 Subjects
Abstract:
... Algae are often used as live feed for aquatic animals and widely used in the aquaculture industry. Both algal cultivation and algal blooms can lead to algal cell aggregation. High-biomass algae will lead to the accumulation of toxic and harmful substances if they are present in algal cells, thus adversely affecting the environment or the food chain. Retinoids have been detected in algal cells, and ...
DOI:
10.1016/j.aquaculture.2022.738758

4. Diabetes Aggravates Photoreceptor Pathologies in a Mouse Model for Ocular Vitamin A Deficiency

Author:
Srinivasagan Ramkumar; Vipul M. Parmar; Jean Moon; Chieh Lee; Patricia R. Taylor; Johannes von Lintig
Source:
Antioxidants 2022 v.11 no.6 pp. -
ISSN:
2076-3921
Subject:
vitamin A; vitamin A deficiency,   etc   ; blood serum; diabetes; homeostasis; liver; mice; phenotype; photoreceptors;     Show all 9 Subjects
Abstract:
... Emerging evidence indicates that diabetes disturbs photoreceptor function and vitamin A homeostasis. However, the biochemical basis of this phenotype is not well established. Here, we compared the effects of streptozotocin-induced diabetes in wild-type (WT) mice and Stra6⁻/⁻ mice, a mouse model for ocular vitamin A deficiency. After 8 weeks, diabetes increased serum retinyl esters in mice of both ...
DOI:
10.3390/antiox11061142

5. Breast Milk Retinol Levels after Vitamin A Supplementation at Different Postpartum Amounts and Intervals

Author:
Danielle S. Bezerra; Andressa T. A. de Melo; Kátia C. de A. N. de Oliveira; Karoline Q. M. A. de Araújo; Monalisa S. M. de F. Medeiros; Flávia A. P. S. dos Santos; Jeane F. P. Medeiros; Mayara S. R. Lima; Ana Gabriella C. L. da Silva; Karla Danielly da S. Ribeiro; Roberto Dimenstein; Mônica M. Osório
Source:
Nutrients 2022 v.14 no.17 pp. -
ISSN:
2072-6643
Subject:
vitamin A; vitamin A deficiency,   etc   ; breast milk; colostrum; equations; high performance liquid chromatography; risk;     Show all 7 Subjects
Abstract:
... Maternal vitamin A (VA) supplementation in risk areas for Vitamin A deficiency (VAD) was launched to improve the level of this nutrient in nursing mothers and in their breast milk. This longitudinal and randomized study aimed to evaluate the levels of retinol in breast milk after supplementation with VA in varying amounts (200,000 IU or 400,000 IU) and different postpartum intervals. Women were di ...
DOI:
10.3390/nu14173570

6. Cod Liver Oil, but Not Retinoic Acid, Treatment Restores Bone Thickness in a Vitamin A-Deficient Rat

Author:
Richard C. Baybutt; Joseph T. Standard; Daniel Dim; Tim Quinn; Hana Hamdan; Dingbo Lin; Kyle Kunz; Zachary S. Bomstein; Benjamin J. Estorge; Betty Herndon; Hamid Zia; Ahmad Mansour; Manesha Lankachandra; Agostino Molteni
Source:
Nutrients 2022 v.14 no.3 pp. -
ISSN:
2072-6643
Subject:
vitamin A; vitamin A deficiency,   etc   ; cod liver oil; diet; metabolites; osteoblasts; osteoclasts; rats; retinoic acid; weanlings;     Show all 10 Subjects
Abstract:
... Vitamin A plays a prominent role for maintaining optimal bone status, but its impact upon the bone in response to vitamin A deficiency is not well defined. The purpose of this study was to evaluate how replenishing vitamin A by either whole food cod liver oil (COD) or the active metabolite of vitamin A, retinoic acid (RA), altered bone thickness of vitamin A-deficient (VAD) rats. Weanling rats wer ...
DOI:
10.3390/nu14030486

7. Flaviviruses hijack the host microbiota to facilitate their transmission

Author:
Lejla Gul; Tamas Korcsmaros; Neil Hall
Source:
Cell 2022 v.185 no.14 pp. 2395-2397
ISSN:
0092-8674
Subject:
vitamin A,   etc   ; dengue; microbiome; viruses;     Show all 4 Subjects
Abstract:
... Flaviviruses, such as Dengue and Zika viruses, infect millions of people worldwide using mosquitos as vectors. In this issue of Cell, Zhang et al. reveal how these viruses manipulate the skin microbiome of infected hosts in a way that increases vector recruitment and viral spread. They propose vitamin A as a way to counteract the virus and decrease transmission. ...
DOI:
10.1016/j.cell.2022.06.019

8. Evidence to Underpin Vitamin A Requirements and Upper Limits in Children Aged 0 to 48 Months: A Scoping Review

Author:
Lee Hooper; Chizoba Esio-Bassey; Julii Brainard; Judith Fynn; Amy Jennings; Natalia Jones; Bhavesh V. Tailor; Asmaa Abdelhamid; Calvin Coe; Latife Esgunoglu; Ciara Fallon; Ernestina Gyamfi; Claire Hill; Stephanie Howard Wilsher; Nithin Narayanan; Titilopemi Oladosu; Ellice Parkinson; Emma Prentice; Meysoon Qurashi; Luke Read; Harriet Getley; Fujian Song; Ailsa A. Welch; Peter Aggett; Georg Lietz
Source:
Nutrients 2022 v.14 no.3 pp. -
ISSN:
2072-6643
Subject:
vitamin A; vitamin A deficiency,   etc   ; biofortification; cassava; corn; databases; food fortification; isotope labeling; risk; staple foods; systematic review;     Show all 11 Subjects
Abstract:
... Vitamin A deficiency is a major health risk for infants and children in low- and middle-income countries. This scoping review identified, quantified, and mapped research for use in updating nutrient requirements and upper limits for vitamin A in children aged 0 to 48 months, using health-based or modelling-based approaches. Structured searches were run on Medline, EMBASE, and Cochrane Central, fro ...
DOI:
10.3390/nu14030407

9. Potential of pumpkin to combat vitamin A deficiency during complementary feeding in low and middle income countries: variety, provitamin A carotenoid content and retention, and dietary reference intakes

Author:
Edward Buzigi; Kirthee Pillay; Muthulisi Siwela
Source:
Critical reviews in food science and nutrition 2022 v.62 no.22 pp. 6103-6112
ISSN:
1549-7852
Subject:
vitamin A; vitamin A deficiency,   etc   ; Adequate Intakes; biofortification; children; complementary feeding; complementary foods; food crops; income; pumpkins; risk;     Show all 11 Subjects
Abstract:
... The risk of child vitamin A deficiency (VAD) in low and middle income countries (LMICs) begins during the age range of complementary feeding (6–24 months), when children are fed complementary foods (CFs) deficient in vitamin A. However, pumpkin, a source of provitamin A carotenoids (PVACs) is widely cultivated in LMICs, but underutilized as a complementary food. Moreover, when consumed by humans, ...
DOI:
10.1080/10408398.2021.1896472

10. Understanding the role of vitamin A and its precursors in the immune system

Author:
Murat Gürbüz; Şule Aktaç
Source:
Nutrition clinique et métabolisme 2022 v.36 no.2 pp. 89-98
ISSN:
0985-0562
Subject:
vitamin A; vitamin A deficiency,   etc   ; epithelium; humans; immune response; immune system; mucus; retinoic acid; retinoic acid receptors; secretion; vision;     Show all 11 Subjects
Abstract:
... Vitamin A is the first defined vitamin and is also known as an anti-inflammatory micronutrient. Although the primary biological function is preservation of epithelial tissue integrity, vision and growth, vitamin A also plays a role in immune system regulation. It is known that susceptibility to infections increases in developing countries due to vitamin A deficiency. Therefore, the purpose of this ...
DOI:
10.1016/j.nupar.2021.10.002

11. A review on the trends of maize biofortification in alleviating hidden hunger in sub-Sahara Africa

Author:
Selly D. Msungu; Arnold A. Mushongi; Pavithravani B. Venkataramana; Ernest R. Mbega
Source:
Scientia horticulturae 2022 v.299 pp. 111029
ISSN:
0304-4238
Subject:
vitamin A; vitamin A deficiency,   etc   ; biofortification; carotenes; corn; cost effectiveness; diet; food fortification; hunger; longevity; systematic review; Sub-Saharan Africa;     Show all 12 Subjects
Abstract:
... Micronutrient deficiency is a major problem affecting many people in developing countries who solely depend on maize as their single source of calories. Vitamin A deficiency is one of the health problems associated with micronutrient deficiency. It is caused by insufficient intake of food rich in vitamin A among vulnerable groups leading to impaired growth, reduced life span, and economic losses a ...
DOI:
10.1016/j.scienta.2022.111029

12. Seasonal and Feeding System Effects on Qualitative Parameters of Bovine Milk Produced in the Abruzzo Region (Italy)

Author:
Marco Florio; Claudia Giannone; Andrea Ianni; Francesca Bennato; Lisa Grotta; Giuseppe Martino
Source:
Agriculture (Basel) 2022 v.12 no.7 pp. -
ISSN:
2077-0472
Subject:
vitamin A,   etc   ; agriculture; milk; spring; summer; Italy;     Show all 6 Subjects
Abstract:
... The aim of this study was to examine variations in cow milk composition as a function of breeding system and seasonality. This study was carried out in 16 dairy farms located in the Abruzzo region (Central Italy), equally distributed between farms that adopt grazing in the spring and summer months, and farms where the intensive system is exploited. Milk was sampled in all seasons in each of the fa ...
DOI:
10.3390/agriculture12070917

13. Prevalence of vitamin A deficiency and dietary inadequacy in Indian school-age children and adolescents

Author:
Geereddy Bhanuprakash Reddy; Tattari Shalini; Santu Ghosh; Raghu Pullakhandam; Boiroju Naveen Kumar; Bharati Kulkarni; Avula Laxmaiah; Umesh Kapil; Sila Deb; Rajkumar Hemalatha; Anura V. Kurpad; Harshpal S. Sachdev
Source:
European journal of nutrition 2022 v.61 no.1 pp. 197-209
ISSN:
1436-6207
Subject:
vitamin A; vitamin A deficiency,   etc   ; blood serum; hypervitaminosis A; inflammation; milk consumption; nutrition surveys; oils; risk; risk assessment; socioeconomic status; India;     Show all 12 Subjects
Abstract:
... PURPOSE: There are no representative estimates of vitamin A deficiency (VAD) and risk of vitamin A (VA) dietary inadequacy in Indian children and adolescents. To evaluate, from national surveys, the prevalence of VAD measured by serum retinol concentrations (< 0.7 µmol/L or < 20 µg/dL), and the risk of VA dietary inadequacy and excess intake beyond the tolerable upper limit (TUL). METHODS: Nationa ...
DOI:
10.1007/s00394-021-02636-7

14. Cis-trans retinol isomerisation: Influence of microorganisms during the production of pasta filata cheeses

Author:
Serena Niro; Alessandra Fratianni; Patrizio Tremonte; Silvia Jane Lombardi; Elena Sorrentino; Pamela Manzi; Gianfranco Panfili
Source:
International dairy journal 2022 v.133 pp. 105441
ISSN:
0958-6946
Subject:
vitamin A,   etc   ; isomerization; lactic acid; pasta filata cheese; saponification;     Show all 5 Subjects
Abstract:
... The isomerisation index, or degree of retinol isomerisation (DRI), i.e. the percentage ratio between 13-cis and all-trans retinol, could be used as process and product index in dairy products. To better investigate microbial influence on retinol isomerisation, retinol isomerisation and microbial levels have been monitored during the technological process and the storage of different “pasta filata” ...
DOI:
10.1016/j.idairyj.2022.105441

15. Mice Lacking the Systemic Vitamin A Receptor RBPR2 Show Decreased Ocular Retinoids and Loss of Visual Function

Author:
Rakesh Radhakrishnan; Matthias Leung; Heidi Roehrich; Stephen Walterhouse; Altaf A. Kondkar; Wayne Fitzgibbon; Manas R. Biswal; Glenn P. Lobo
Source:
Nutrients 2022 v.14 no.12 pp. -
ISSN:
2072-6643
Subject:
vitamin A; vitamin A deficiency,   etc   ; Danio rerio; blood; diet; electroretinography; homeostasis; intestines; knockout mutants; lipophilicity; liver; models; opsin; photoreceptors; phototransduction; retina; retinol-binding protein;     Show all 17 Subjects
Abstract:
... The systemic transport of dietary vitamin A/all-trans retinol bound to RBP4 into peripheral tissues for storage is an essential physiological process that continuously provides visual chromophore precursors to the retina under fasting conditions. This mechanism is critical for phototransduction, photoreceptor cell maintenance and survival, and in the support of visual function. While the membrane ...
DOI:
10.3390/nu14122371

16. Global Burden of Vitamin A Deficiency in 204 Countries and Territories from 1990–2019

Author:
Tian Zhao; Shiwei Liu; Ruijie Zhang; Zhenping Zhao; Hu Yu; Liyuan Pu; Li Wang; Liyuan Han
Source:
Nutrients 2022 v.14 no.5 pp. -
ISSN:
2072-6643
Subject:
vitamin A deficiency,   etc   ; confidence interval; public health; Niger; Somalia;     Show all 5 Subjects
Abstract:
... Vitamin A deficiency (VAD) is one of the important public health issues worldwide. However, a detailed understanding of the incidence and disability-adjusted life years (DALYs) due to VAD in recent years is lacking. We aimed to estimate the incidence and DALYs of VAD at global, regional, and national levels in terms of sex, age, and socio-demographic index (SDI). Using data from the 2019 Global Bu ...
DOI:
10.3390/nu14050950

17. Fenretinide inhibits vitamin A formation from β-carotene and regulates carotenoid levels in mice

Author:
Anthony P. Miller; Molly Black; Jaume Amengual
Source:
Biochimica et biophysica acta 2022 v.1867 no.2 pp. 159070
ISSN:
1388-1981
Subject:
vitamin A; vitamin A deficiency,   etc   ; COVID-19 infection; absorption; cell culture; cystic fibrosis; enzymes; homeostasis; human health; intestines; night blindness; retinol-binding protein; vitamin E;     Show all 13 Subjects
Abstract:
... N-[4-hydroxyphenyl]retinamide, commonly known as fenretinide, a synthetic retinoid with pleiotropic benefits for human health, is currently utilized in clinical trials for cancer, cystic fibrosis, and COVID-19. However, fenretinide reduces plasma vitamin A levels by interacting with retinol-binding protein 4 (RBP4), which often results in reversible night blindness in patients. Cell culture and in ...
DOI:
10.1016/j.bbalip.2021.159070
CHORUS:
10.1016/j.bbalip.2021.159070

18. A comprehensive review on carotenoids in foods and feeds: status quo, applications, patents, and research needs

Author:
Antonio J. Meléndez-Martínez; Anamarija I. Mandić; Filippos Bantis; Volker Böhm; Grethe Iren A. Borge; Mladen Brnčić; Anette Bysted; M. Pilar Cano; M. Graça Dias; Anjo Elgersma; Martina Fikselová; Javier García-Alonso; Daniele Giuffrida; Vanessa S. S. Gonçalves; Dámaso Hornero-Méndez; Kristina Kljak; Vera Lavelli; George A. Manganaris; Paula Mapelli-Brahm; Milan Marounek; Begoña Olmedilla-Alonso; María Jesús Periago-Castón; Adela Pintea; Jeremiah J. Sheehan; Vesna Tumbas Šaponjac; Magdaléna Valšíková-Frey; Lieven Van Meulebroek; Nora O’Brien
Source:
Critical reviews in food science and nutrition 2022 v.62 no.8 pp. 1999-2049
ISSN:
1549-7852
Subject:
vitamin A,   etc   ; bioactive compounds; diet; food science; health promotion; humans;     Show all 6 Subjects
Abstract:
... Carotenoids are isoprenoids widely distributed in foods that have been always part of the diet of humans. Unlike the other so-called food bioactives, some carotenoids can be converted into retinoids exhibiting vitamin A activity, which is essential for humans. Furthermore, they are much more versatile as they are relevant in foods not only as sources of vitamin A, but also as natural pigments, ant ...
DOI:
10.1080/10408398.2020.1867959

19. Nucleotide variation in the phytoene synthase (ClPsy1) gene contributes to golden flesh in watermelon (Citrullus lanatus L.)

Author:
Shi Liu; Zhongqi Gao; Xuezheng Wang; Feishi Luan; Zuyun Dai; Zhongzhou Yang; Qian Zhang
Source:
Theoretical and applied genetics 2022 v.135 no.1 pp. 185-200
ISSN:
0040-5752
Subject:
vitamin A; vitamin A deficiency,   etc   ; Citrullus lanatus; color; exons; genetic analysis; genetic variation; germplasm; loci; phytoene synthase; promoter regions; recessive genes; sequence alignment; watermelons; zinc finger motif;     Show all 15 Subjects
Abstract:
... KEY MESSAGE: A gene controlling golden flesh trait in watermelon was discovered and fine mapped to a 39.08 Kb region on chromosome 1 through a forward genetic strategy, and Cla97C01G008760 (annotated as phytoene synthase protein, ClPsy1) was recognized as the most likely candidate gene. Vitamin A deficiency is a worldwide public nutrition problem, and β-carotene is the precursor for vitamin A synt ...
DOI:
10.1007/s00122-021-03958-0

20. Evolving Patterns of Nutritional Deficiencies Burden in Low- and Middle-Income Countries: Findings from the 2019 Global Burden of Disease Study

Author:
Jingjing Liu; Xinye Qi; Xing Wang; Yinghua Qin; Shengchao Jiang; Liyuan Han; Zheng Kang; Linghan Shan; Libo Liang; Qunhong Wu
Source:
Nutrients 2022 v.14 no.5 pp. -
ISSN:
2072-6643
Subject:
vitamin A deficiency,   etc   ; iodine deficiency; protein energy malnutrition; Bhutan; Mali; Zimbabwe;     Show all 6 Subjects
Abstract:
... Low- and middle-income countries (LMICs) suffered the most from nutritional deficiencies (NDs). Although decades of efforts have reduced it, little is known about the changing trajectory of ND burden in LMICs. By extracting data of the Global Burden of Diseases, Injuries, and Risk Factors Study 2019, we calculated indicators of incidence and disability-adjusted life years (DALYs) to measure the bu ...
DOI:
10.3390/nu14050931