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1. Highly sensitive phage-magnetic-chemiluminescent enzyme immunoassay for determination of zearalenone

Author:
Liu, Ruxia; Shi, Ruirui; Zou, Wenting; Chen, Wenhua; Yin, Xianchao; Zhao, Fengchun; Yang, Zhengyou
Source:
Food chemistry 2020 v.325 pp. 126905
ISSN:
0308-8146
Subject:
zearalenone,   etc   ; antigens; chemiluminescence; corn; enzyme-linked immunosorbent assay; high performance liquid chromatography; inhibitory concentration 50; nanoparticles;     Show all 8 Subjects
Abstract:
... Here we demonstrate a novel phage-magnetic-chemiluminescent enzyme immunoassay (P-MCLEIA) for detection of zearalenone (ZEN). The P-MCLEIA was more efficient than conventional ELISA through several improvements. In the P-MCLEIA, magnetic nanoparticles were replaced of microplates as solid phases to reduce the whole incubation time within 40 min. Phage-mimotope was replaced of chemosynthetic antige ...
DOI:
10.1016/j.foodchem.2020.126905

2. Broad-spectrum detection of zeranol and its analogues by a colloidal gold-based lateral flow immunochromatographic assay in milk

Author:
Yin, Mengqi; Hu, Xiaofei; Sun, Yaning; Xing, Yunrui; Xing, Guangxu; Wang, Yanwei; Li, Qingmei; Wang, Yao; Deng, Ruiguang; Zhang, Gaiping
Source:
Food chemistry 2020 v.321 pp. 126697
ISSN:
0308-8146
Subject:
zearalenone,   etc   ; gold; growth promotion; immunoaffinity chromatography; inhibitory concentration 50; livestock; milk; monoclonal antibodies; zearalenol; zeranol;     Show all 10 Subjects
Abstract:
... Based on colloidal gold and broad-spectrum monoclonal antibody that binds to zeranol and its five analogues with high sensitivity, a lateral flow immunochromatographic assay (LFIA) in a competitive format was developed to specifically determine residues of zeranol, an illegal growth promoter in livestock. In this study, the assay had high sensitivity and was broad-spectrum only for zeranol and its ...
DOI:
10.1016/j.foodchem.2020.126697

3. Nationwide survey reveals high diversity of Fusarium species and related mycotoxins in Brazilian rice: 2014 and 2015 harvests

Author:
Moreira, Gláucia M.; Nicolli, Camila P.; Gomes, Larissa B.; Ogoshi, Cláudio; Scheuermann, Klaus K.; Silva-Lobo, Valácia L.; Schurt, Daniel A.; Ritieni, Alberto; Moretti, Antonio; Pfenning, Ludwig H.; Del Ponte, Emerson M.
Source:
Food control 2020 v.113 pp. 107171
ISSN:
0956-7135
Subject:
zearalenone,   etc   ; Fusarium chlamydosporum; Fusarium fujikuroi; Fusarium graminearum; deoxynivalenol; flour; hulls; national surveys; neosolaniol; rice; Brazil;     Show all 11 Subjects
Abstract:
... Ninety three samples of rice were obtained from both research and commercial plots at eight rice-growing regions of Brazil. These were assessed for the presence of Fusarium species complex and 14 mycotoxins. A total of 352 Fusarium-like isolates were obtained from 85% of the samples and assigned to four species complexes (SC) based on morphological identification. F. incarnatum-equiseti was the mo ...
DOI:
10.1016/j.foodcont.2020.107171

4. Dietary exposure to mycotoxins in the French infant total diet study

Author:
Vin, Karine; Rivière, Gilles; Leconte, Stéphane; Cravedi, Jean-Pierre; Fremy, Jean Marc; Oswald, Isabelle P.; Roudot, Alain-Claude; Vasseur, Paule; Jean, Julien; Hulin, Marion; Sirot, Véronique
Source:
Food and chemical toxicology 2020 v.140 pp. 111301
ISSN:
0278-6915
Subject:
zearalenone,   etc   ; Total Diet Study; aflatoxins; children; deoxynivalenol; dietary exposure; fumonisins; nivalenol; ochratoxin A; patulin;     Show all 10 Subjects
Abstract:
... The present study evaluated the exposure of children aged from one to 36 months to seven groups of mycotoxins, in the context of the infant French Total Diet Study (iTDS). Exposure was then compared to the health-based guidance values (HBGVs) for each mycotoxin. The value of the 90th percentile of exposure to nivalenol, patulin, fumonisins and zearalenone was less than 40% of the HBGV considered r ...
DOI:
10.1016/j.fct.2020.111301

5. Mycotoxins in maize harvested in Republic of Serbia in the period 2012–2015. Part 1: Regulated mycotoxins and its derivatives

Author:
Kos, Jovana; Janić Hajnal, Elizabet; Malachová, Alexandra; Steiner, David; Stranska, Milena; Krska, Rudolf; Poschmaier, Birgit; Sulyok, Michael
Source:
Food chemistry 2020 v.312 pp. 126034
ISSN:
0308-8146
Subject:
zearalenone,   etc   ; aflatoxin B1; corn; deoxynivalenol; drought; fumonisins; liquid chromatography; mass spectrometry; ochratoxin A; Serbia;     Show all 10 Subjects
Abstract:
... The main objective of this study was to apply a liquid chromatography–tandem mass spectrometric method to investigate the presence of 20 mycotoxins in 204 maize samples harvested in Northern Serbia in the period 2012–2015, including seasons with extreme drought (2012), hot and dry conditions (2013 and 2015) and extreme precipitation (2014). Between 2 and 20 mycotoxins contaminated examined samples ...
DOI:
10.1016/j.foodchem.2019.126034

6. Peroxidase as a simultaneous degradation agent of ochratoxin A and zearalenone applied to model solution and beer

Author:
de Oliveira Garcia, Sabrina; Sibaja, Karen Vanessa Marimón; Nogueira, Wesclen Vilar; Feltrin, Ana Carla Penteado; Pinheiro, Diean Fabiano Alvares; Cerqueira, Maristela Barnes Rodrigues; Badiale Furlong, Eliana; Garda-Buffon, Jaqueline
Source:
Food research international 2020 v.131 pp. 109039
ISSN:
0963-9969
Subject:
zearalenone,   etc   ; Armoracia rusticana; beers; enzyme kinetics; humans; hydrogen peroxide; ionic strength; ochratoxin A; pH; peroxidase; potassium;     Show all 11 Subjects
Abstract:
... The aim of this study was to evaluate the action of the commercial peroxidase (POD) enzyme (Armoracia rusticana) on the simultaneous degradation of ochratoxin A (OTA) and zearalenone (ZEA) in model solution and beer. For this purpose, the reaction parameters for POD action were optimized, POD application in the degradation of mycotoxins in model solution and beer was evaluated and the kinetic para ...
DOI:
10.1016/j.foodres.2020.109039

7. Zearalenone-induced aberration in the composition of the gut microbiome and function impacts the ovary reserve

Author:
Tan, Shaojing; Ge, Wei; Wang, Junjie; Liu, Wenxiang; Zhao, Yong; Shen, Wei; Li, Lan
Source:
Chemosphere 2020 v.244 pp. 125493
ISSN:
0045-6535
Subject:
zearalenone,   etc   ; Lachnospiraceae; diet; dose response; intestinal microorganisms; lysophosphatidylcholine; metabolism; metabolites; metagenomics; mice; reproduction; sequence analysis; toxicity;     Show all 13 Subjects
Abstract:
... Zearalenone (ZEA), as a contaminant commonly found in our daily diet, has been widely studied for its toxicity. However, the exact mechanism underlying ZEA induced reproduction disorders remains unclear. Our study aimed to elucidate the underlying relationship between aberrations in the gut microbiota and the degeneration of the ovarian reserve following exposure to ZEA. Four-week-old mice were tr ...
DOI:
10.1016/j.chemosphere.2019.125493

8. Degradation mechanism for Zearalenone ring-cleavage by Zearalenone hydrolase RmZHD: A QM/MM study

Author:
Zhou, Jie; Zhu, Ledong; Chen, Jinfeng; Wang, Wei; Zhang, Ruiming; Li, Yanwei; Zhang, Qingzhu; Wang, Wenxing
Source:
The Science of the total environment 2020 v.709 pp. 135897
ISSN:
0048-9697
Subject:
zearalenone,   etc   ; active sites; amino acids; bioremediation; endocrine-disrupting chemicals; humans; hydrogen bonding; hydrolases; mutation; quantum mechanics;     Show all 10 Subjects
Abstract:
... The danger of zearalenone (ZEN) as an endocrine disruptor to humans and the environment has aroused increasing attention. In this study, we implemented the quantum mechanics/molecular mechanics (QM/MM) method to investigate the degradation mechanism of ZEN hydrolase (RmZHD) toward ZEN at the atomic level. The degradation process involves two concerted reaction pathways, where the active site conta ...
DOI:
10.1016/j.scitotenv.2019.135897

9. Synthesis and application of magnetic-surfaced pseudo molecularly imprinted polymers for zearalenone pretreatment in cereal samples

Author:
Huang, Zhipeng; He, Juan; Li, Huayu; Zhang, Ming; Wang, Huige; Zhang, Yunxia; Li, Yuanyuan; You, Liqin; Zhang, Shusheng
Source:
Food chemistry 2020 v.308 pp. 125696
ISSN:
0308-8146
Subject:
zearalenone,   etc   ; adsorbents; corn; fungi; iron oxides; magnetism; molecular imprinting; nanotubes; oats; polymers; wheat;     Show all 11 Subjects
Abstract:
... Zearalenone (ZEA) is a fungal contaminant widely found in grains. In cereal samples, trace zearalenone was extracted and enriched using magnetic-surfaced pseudo molecularly imprinted polymers (SPMIPs) and detected. SPMIPs were prepared with Fe₃O₄ as the magnetic core, modified halloysites nanotubes as supporting materials, and selective imprinted polymers as shells. Vinyl was modified on the surfa ...
DOI:
10.1016/j.foodchem.2019.125696

10. Magnetic hyperbranched molecularly imprinted polymers for selective enrichment and determination of zearalenone in wheat proceeded by HPLC-DAD analysis

Author:
Zhang, Yan; Liu, Donghao; Peng, Jun; Cui, Yanru; Shi, Yi; He, Hua
Source:
Talanta 2020 v.209 pp. 120555
ISSN:
0039-9140
Subject:
zearalenone,   etc   ; adsorption; binding capacity; high performance liquid chromatography; magnetism; molecular imprinting; polymers; solvents; standard deviation; wheat;     Show all 10 Subjects
Abstract:
... A novel magnetic surface molecular imprinted polymers with 2, 4, 6-trisacrylamido-3, 5-triazine (TAT) as a functional monomer was successfully synthesized and used for the enrichment and determination of zearalenone. The molecular imprinting is reported herein at first time for application of zearalenone in wheat. The magnetic imprinted materials possessed excellent magnetism and uniform appearanc ...
DOI:
10.1016/j.talanta.2019.120555

11. Methodology development based on “dilute and shoot” and QuEChERS for determination of multiple mycotoxins in cocoa by LC-MS/MS

Author:
Abreu, Daiane Cássia Pereira; da Silva Oliveira, Fabiano Aurélio; Vargas, Eugenia Azevedo; Madureira, Fernando Diniz; Magalhães, Elisangela Jaqueline; da Silva, Lucas Pinto; Saczk, Adelir Aparecida
Source:
Analytical and bioanalytical chemistry 2020 v.412 no.8 pp. 1757-1767
ISSN:
1618-2642
Subject:
zearalenone,   etc   ; acidification; cocoa beans; foods; liquid chromatography; standard deviation; tandem mass spectrometry; tenuazonic acid;     Show all 8 Subjects
Abstract:
... This work proposes an extraction method based on the “dilute and shoot” approach and QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) for the simultaneous determination of 42 mycotoxins (34 quantified and 8 qualitatively studied) in dried cocoa bean samples. The purpose of the developed methodology was the reduction of co-extractives from the matrix and an efficient extraction without a ...
DOI:
10.1007/s00216-020-02390-5

12. Developments in mycotoxin analysis: an update for 2018-19

Author:
Tittlemier, S.A.; Cramer, B.; Dall’Asta, C.; Iha, M.H.; Lattanzio, V.M.T.; Maragos, C.; Solfrizzo, M.; Stranska, M.; Stroka, J.; Sumarah, M.
Source:
World mycotoxin journal 2020 v.13 no.1 pp. 3-24
ISSN:
1875-0796
Subject:
zearalenone,   etc   ; Alternaria; aflatoxins; analytical methods; ergot alkaloids; fumonisins; immunoassays; ochratoxins; patulin; trichothecenes;     Show all 10 Subjects
Abstract:
... This review summarises developments on the analysis of various matrices for mycotoxins that have been published in the period from mid-2018 to mid-2019. Analytical methods to determine aflatoxins, Alternaria toxins, ergot alkaloids, fumonisins, ochratoxins, patulin, trichothecenes, and zearalenone are covered in individual sections. Advances in sampling strategies are also discussed in a dedicated ...
DOI:
10.3920/WMJ2019.2535

13. Soft glass multi-channel capillaries as a platform for bioimprinting

Author:
Burmistrova, Natalia A.; Pidenko, Pavel S.; Pidenko, Sergey A.; Zacharevich, Andrey M.; Skibina, Yulia S.; Beloglazova, Natalia V.; Goryacheva, Irina Yu
Source:
Talanta 2020 v.208 pp. 120445
ISSN:
0039-9140
Subject:
zearalenone,   etc   ; detection limit; enzyme-linked immunosorbent assay; food contamination; glass; molecular imprinting; ovalbumin; screening; wheat;     Show all 9 Subjects
Abstract:
... Multi-channel capillaries (MC) formed from thousands individual microcapillaries with diameters ranging 10–100 μm are of a great interest for their use as platforms for molecular imprinting due to their relatively large surface area, high mechanical stability and possibility of facile integration in sensor systems. The manuscript proposes a new format of immunoassay based on imprinted protein immo ...
DOI:
10.1016/j.talanta.2019.120445

14. Effect of acid-treated and hexadecyltrimethylammonium bromide–modified montmorillonites on adsorption performance of mycotoxins

Author:
Mao, Jiaqi; Lv, Guanglie; Zhou, Renxian
Source:
Environmental science and pollution research international 2020 v.27 no.4 pp. 4284-4293
ISSN:
0944-1344
Subject:
zearalenone,   etc   ; acid treatment; active sites; adsorption; aflatoxin B1; cetyltrimethylammonium bromide; deoxynivalenol; hydrophobicity; montmorillonite; pH;     Show all 10 Subjects
Abstract:
... A series of modified montmorillonites treated by acid and hexadecyltrimethylammonium bromide (HTAB) were prepared and characterized, and their adsorption performances for three mycotoxins (aflatoxin B1, zearalenone, and deoxynivalenol) were evaluated at pH 2.8 and 8.0, respectively. The results indicate that the layers of raw montmorillonite are exfoliated after acid treatment and more active site ...
DOI:
10.1007/s11356-019-07118-2

15. Microbial Degradation of Zearalenone by a Novel Microbial Consortium, NZDC-6, and Its Application on Contaminated Corncob by Semisolid Fermentation

Author:
Wang, Yi; Zhao, Chunxia; Zhang, Dongdong; Zhao, Mingming; Peng, Maomin; Guo, Peng; Cui, Zongjun
Source:
Journal of agricultural and food chemistry 2020 v.68 no.6 pp. 1634-1644
ISSN:
1520-5118
Subject:
zearalenone,   etc   ; biodegradation; corn; corn cobs; dissolved oxygen; environmental factors; fermentation; pH; temperature; zearalenol;     Show all 10 Subjects
Abstract:
... A novel microbial consortium (NZDC-6) was screened and characterized to detoxify the estrogenic mycotoxin zearalenone (ZEA), which commonly contaminates maize and is a major threat to food and health security. We found NZDC-6 to be thermophilic and highly effective, with a 90.3% ZEA degradation ratio at an optimum temperature of 60 °C. NZDC-6 was also effective at degrading the more estrogenic ZEA ...
DOI:
10.1021/acs.jafc.9b05343

16. Carry-over assessment of fumonisins and zearalenone to poultry tissues after exposure of chickens to a contaminated diet – A study implementing stable-isotope dilution assay and UHPLC-MS/MS

Author:
Hort, Vincent; Nicolas, Marina; Travel, Angélique; Jondreville, Catherine; Maleix, Corentin; Baéza, Elisabeth; Engel, Erwan; Guérin, Thierry
Source:
Food control 2020 v.107 pp. 106789
ISSN:
0956-7135
Subject:
zearalenone,   etc   ; animal tissues; chickens; detection limit; diet; fumonisins; liver; males; metabolites; muscles; stable isotopes;     Show all 11 Subjects
Abstract:
... This study assessed the transfer of fumonisins B1 and B2 (FBs), zearalenone (ZEA) and zearalenone metabolites α-zearalanol (α-ZAL) and α-zearalenol (α-ZEL) to poultry tissues. Two experimental groups of 9 male chickens each were exposed for 8 weeks to a contaminated diet (FB group: 12.7 mg FB1 + FB2 kg⁻¹, ZEA group: 0.40 mg ZEA kg⁻¹). To measure the carry-over from feed to animal tissues (liver an ...
DOI:
10.1016/j.foodcont.2019.106789

17. An in silico structural approach to characterize human and rainbow trout estrogenicity of mycotoxins: Proof of concept study using zearalenone and alternariol

Author:
Dellafiora, Luca; Oswald, Isabelle P.; Dorne, Jean-Lou; Galaverna, Gianni; Battilani, Paola; Dall'Asta, Chiara
Source:
Food chemistry 2020 v.312 pp. 126088
ISSN:
0308-8146
Subject:
zearalenone,   etc   ; Oncorhynchus mykiss; computer simulation; endocrine-disrupting chemicals; humans; metabolites; molecular dynamics; pharmacokinetics; toxicity; toxicology; trout; zearalenol;     Show all 12 Subjects
Abstract:
... The mycotoxins zearalenone and alternariol may contaminate food and feed raising toxicological concerns due to their estrogenicity. Inter-species differences in their toxicokinetics and toxicodynamics may occur depending on evolution of taxa-specific traits. As a proof of principle, this manuscript investigates the comparative toxicodynamics of zearalenone, its metabolites (alpha-zearalenol and be ...
DOI:
10.1016/j.foodchem.2019.126088

18. Pseudomonas simiae effects on the mycotoxin formation by fusaria and alternaria in vitro and in a wheat field

Author:
Müller, Thomas; Lentzsch, Peter; Behrendt, Undine; Barkusky, Dietmar; Müller, Marina E. H.
Source:
Mycotoxin research 2020 v.36 no.2 pp. 147-158
ISSN:
0178-7888
Subject:
zearalenone,   etc   ; Alternaria; Fusarium; Pseudomonas; Triticum; air; antagonists; bacteria; biological control; deoxynivalenol; plant pathogenic fungi; seeds; tenuazonic acid; winter wheat;     Show all 14 Subjects
Abstract:
... Fluorescent pseudomonads colonizing wheat ears have a high antagonistic potential against phytopathogenic fungi. To check this hypothesis, the bacterial antagonist Pseudomonas simiae 9 ʳⁱᶠ⁺/ᵏᵃⁿ⁺ was spray-inoculated onto the ears of winter wheat in a locally demarcated experimental field plot. Fusarium and Alternaria fungi naturally occurring on the ears and the formation of their mycotoxins in th ...
DOI:
10.1007/s12550-019-00379-3

19. Investigations on organo-montmorillonites modified by binary nonionic/zwitterionic surfactant mixtures for simultaneous adsorption of aflatoxin B1 and zearalenone

Author:
Sun, Zhiming; Lian, Chi; Li, Chunquan; Zheng, Shuilin
Source:
Journal of colloid and interface science 2020 v.565 pp. 11-22
ISSN:
0021-9797
Subject:
zearalenone,   etc   ; adsorbents; adsorption; aflatoxin B1; betaine; carbon; hydrophobic bonding; hydrophobicity; microstructure; pH; polyethylene glycol; sorption isotherms; surfactants; zwitterions;     Show all 14 Subjects
Abstract:
... To solve the problem of simultaneous adsorption of polar and weak polar mycotoxins, organo-montmorillonites modified by binary surfactant mixtures (NZMts), including polyoxyethylene ether (OP-10) and lauramidopropyl betaine (LAB-35), were synthesized for the simultaneous removal of aflatoxin B₁ (AFB₁) and zearalenone (ZER). The microstructure, interface and pore structure characteristics of NZMts ...
DOI:
10.1016/j.jcis.2020.01.013

20. Comparative toxicokinetics of Fusarium mycotoxins in pigs and humans

Author:
Schelstraete, Wim; Devreese, Mathias; Croubels, Siska
Source:
Food and chemical toxicology 2020 v.137 pp. 111140
ISSN:
0278-6915
Subject:
zearalenone,   etc   ; Fusarium; T-2 toxin; absorption; animal models; deoxynivalenol; excretion; fumonisin B1; humans; metabolites; pharmacokinetics; risk assessment; swine; toxicity;     Show all 14 Subjects
Abstract:
... Mycotoxins frequently contaminate food and feed materials, posing a threat to human and animal health. Fusarium species produce important mycotoxins with regard to their occurrence and toxicity, especially deoxynivalenol (DON), fumonisin B1 (FB1), zearalenone (ZEN) and T-2 toxin (T-2). The susceptibility of an animal species towards the effects of these toxins in part depends on the absorption, di ...
DOI:
10.1016/j.fct.2020.111140