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1. Zein structure and its hidden zearalenone: Effect of zein extraction methods

Author:
Hongxia Tan; Hongyuan Zhou; Ting Guo; Jiaxin Li; Chi Zhang; Shuo Wang; Yuhao Zhang; Liang Ma
Source:
Food chemistry 2022 v.374 pp. 131563
ISSN:
0308-8146
Subject:
zearalenone,   etc   ; corn; denaturation; food chemistry; hydrophobicity; zein;     Show all 6 Subjects
Abstract:
... Zein, the plant protein, has received great attention in the last years. However, hidden zearalenone (ZEN), the zein-bound ZEN present in zein would have a great hazard to humans and animals. To date, the fates of hidden ZEN under different extraction methods of zein have not been clarified. In this study, the effect of zein extraction methods on conversion of free ZEN with hidden ZEN and its corr ...
DOI:
10.1016/j.foodchem.2021.131563

2. Dual-Enzyme-Based Signal-Amplified Aptasensor for Zearalenone Detection by Using CRISPR-Cas12a and Nt.AlwI

Author:
Xijing Yao; Qingli Yang; Yifei Wang; Chuanlin Bi; Han Du; Wei Wu
Source:
Foods 2022 v.11 no.3 pp. -
ISSN:
2304-8158
Subject:
zearalenone,   etc   ; aptasensors; detection limit; enzymes; fluorescence; humans; oligonucleotides;     Show all 7 Subjects
Abstract:
... Zearalenone (ZEN) is harmful to animals and human beings, so it is very important to develop a rapid and sensitive method for the detection of ZEN. In this paper, we proposed a novel ZEN-monitoring method using two aptamers as recognition elements and EnGen LbaCas12a and Nt.AlwI nicking endonuclease as signal amplifiers. When ZEN was present, it bound to the aptamer Z0 and, Z1 was released into so ...
DOI:
10.3390/foods11030487

3. Development of a label-free plasmonic gold nanoparticles aggregates sensor on the basis of charge neutralization for the detection of zearalenone

Author:
Keyu Xing; Juan Peng; Wenyao Chen; Bolong Fang; Daofeng Liu; Shan Shan; Ganggang Zhang; Yina Huang; Weihua Lai
Source:
Food chemistry 2022 v.370 pp. 131365
ISSN:
0308-8146
Subject:
zearalenone,   etc   ; colorimetry; corn; fluorescence; food chemistry; ingestion; nanogold; neutralization;     Show all 8 Subjects
Abstract:
... Mycotoxin contamination of corn has been considered a serious problem because it can accumulate in different organs or tissues via ingestion or skin contact and cause several health problems in humans. We have constructed a label-free, colorimetric, and fluorescence dual-channel sensing platform for the detection of zearalenone. Here, we demonstrate that plasmonic gold nanoparticles aggregates cou ...
DOI:
10.1016/j.foodchem.2021.131365

4. Rapid and sensitive detection of zearalenone in corn using SERS-based lateral flow immunosensor

Author:
Limei Yin; Tianyan You; Hesham R. El-Seedi; Islam M. El-Garawani; Zhiming Guo; Xiaobo Zou; Jianrong Cai
Source:
Food chemistry 2022 v.396 pp. 133707
ISSN:
0308-8146
Subject:
zearalenone,   etc   ; corn; detection limit; food chemistry; immunosensors; rapid methods;     Show all 6 Subjects
Abstract:
... Zearalenone (ZEN) is a universal mycotoxin contaminant in corn and its products. A surface-enhanced Raman scattering (SERS) based test strip was proposed for the detection of ZEN, which had the advantages of simplicity, rapidity, and high sensitivity. Core-shell Au@AgNPs with embedded reporter molecules (4-MBA) were synthesized as SERS nanoprobe, which exhibited excellent SERS signals and high sta ...
DOI:
10.1016/j.foodchem.2022.133707

5. Ultrasensitive fluorometric oligonucleotide immunoassay for the simultaneous and efficient detection of two mycotoxins in agricultural products

Author:
Ming Li; Chenfei Han; Chuqin Yang; Mingna Sun; Jinsheng Duan; Xuchun Qiu; Daolin Du
Source:
Analytical methods 2022 v.14 no.21 pp. 2108-2116
ISSN:
1759-9679
Subject:
zearalenone,   etc   ; fluorescence; fluorometry; immune response; magnetic separation; magnetism; oligonucleotides;     Show all 7 Subjects
Abstract:
... An ultrasensitive fluorometric oligonucleotide immunoassay (UFOIA) based on a fluorometric oligonucleotide and magnetic separation was proposed for the simultaneous detection of two mycotoxins. Two kinds of magnetic nanoparticle (MNP) probes and their corresponding fluorometric oligonucleotide probes were prepared. After the immune reaction, Cy5-linked and 6-FAM-linked oligonucleotides were dissoc ...
DOI:
10.1039/d2ay00367h

6. Temperature and pH levels: Key factors effecting hidden/free zearalenone during maize processing

Author:
Hongxia Tan; Yao Li; Hongyuan Zhou; Ting Guo; Ying Zhou; Yuhao Zhang; Liang Ma
Source:
Food research international 2022 v.160 pp. 111721
ISSN:
0963-9969
Subject:
zearalenone,   etc   ; corn; exposure assessment; food research; pH; temperature; tortillas;     Show all 7 Subjects
Abstract:
... The productions of food, agricultural products and feed involve a variety processing conditions, which can affect the release/binding of zearalenone (ZEN) with macro-components in maize, resulting in the interconversion of hidden ZEN with free ZEN. This interconversion can cause the uncertainties and individual differences in the exposure assessment. To fully overcome this uncertainties of the pot ...
DOI:
10.1016/j.foodres.2022.111721

7. The replacement of main cap domain to improve the activity of a ZEN lactone hydrolase with broad substrate spectrum

Author:
Tianzhi Jiang; Meixing Wang; Xinyu Li; Hui Wang; Guoqiang Zhao; Pan Wu; Zhenghui Lu; Guimin Zhang
Source:
Biochemical engineering journal 2022 v.182 pp. 108418
ISSN:
1369-703X
Subject:
zearalenone,   etc   ; catalytic activity; histidine; hydrolases; protonation; substrate specificity; toxicity;     Show all 7 Subjects
Abstract:
... Zearalenone (ZEN) and its derivatives is a major kind of mycotoxins that being commonly detected in contaminated grain products. ZEN lactone hydrolase (ZHD) can hydrolyze ZEN to produce non-toxic product, providing an environment-friendly way for ZENs detoxification. However, most of ZEN derivatives are more toxic, which leads to a high demand for the novel ZHD with high degradation activity towar ...
DOI:
10.1016/j.bej.2022.108418

8. A Point-of-Care Assay Based on Reflective Phantom Interface (RPI) Technology for Fast, Multi-Toxin Screening in Wheat

Author:
Matteo Salina; Giovanni Tagliabue; Roberta Ghizzoni; Valeria Terzi; Caterina Morcia
Source:
Agronomy 2022 v.12 no.2 pp. -
ISSN:
2073-4395
Subject:
zearalenone,   etc   ; agronomy; computer software; deoxynivalenol; point-of-care systems; wheat;     Show all 6 Subjects
Abstract:
... Mycotoxigenic fungi can colonize small grain cereals causing severe yield losses and grain contaminations. Fusaria can be responsible for the contamination of wheat grains and derived products via several classes of mycotoxins, negatively impacting human and animal health. Among the strategies to control mycotoxins are analytical tools for their identification and quantification from field to food ...
DOI:
10.3390/agronomy12020493

9. Horseradish Peroxidase: Analytical Capabilities in the Determination of Zearalenone

Author:
E. P. Medyantseva; R. M. Beilinson; A. I. Nikolaenko; H. C. Budnikov
Source:
Journal of analytical chemistry 2022 v.77 no.6 pp. 671-680
ISSN:
1061-9348
Subject:
zearalenone,   etc   ; analytical chemistry; deoxynivalenol; enzyme substrates; fullerene; graphene; nanogold; patulin; peroxidase;     Show all 9 Subjects
Abstract:
... The possibility of using the horseradish peroxidase (HRP)–phenol enzyme–substrate system in the development of an amperometric immunoenzyme sensor for the determination of the mycotoxin zearalenone (ZEA) was shown. New immunoenzyme amperometric sensors based on printed graphite electrodes, including those modified with a fullerene/gold nanoparticles and HRP composite, were proposed for the determi ...
DOI:
10.1134/S1061934822060090

10. Relevant Fusarium Mycotoxins in Malt and Beer

Author:
Xenia Pascari; Sonia Marin; Antonio J. Ramos; Vicente Sanchis
Source:
Foods 2022 v.11 no.2 pp. -
ISSN:
2304-8158
Subject:
zearalenone,   etc   ; Fusarium; beers; deoxynivalenol; feed industry; fermentation; fungi; germination; hydrophilicity; malt; metabolites;     Show all 11 Subjects
Abstract:
... Mycotoxins are secondary fungal metabolites of high concern in the food and feed industry. Their presence in many cereal-based products has been numerously reported. Beer is the most consumed alcoholic beverage worldwide, and Fusarium mycotoxins originating from the malted and unmalted cereals might reach the final product. This review aims to describe the possible Fusarium fungi that could infect ...
DOI:
10.3390/foods11020246

11. Aggressiveness and Mycotoxin Production by Fusarium meridionale Compared with F. graminearum on Maize Ears and Stalks in the Field

Author:
Franklin. J. Machado; Aline V. de Barros; Nicole McMaster; David G. Schmale; Lisa J. Vaillancourt; Emerson M. Del Ponte
Source:
Phytopathology 2022 v.112 no.2 pp. 271-277
ISSN:
0031-949X
Subject:
zearalenone,   etc   ; corn; deoxynivalenol; ear rot; nivalenol; pathogenicity; plant pathology; wheat; Brazil;     Show all 9 Subjects
Abstract:
... Fusarium meridionale and F. graminearum both cause Gibberella ear rot (GER) and Gibberella stalk rot (GSR) of maize in Brazil, but the former is much more common. Recent work with two isolates of each from maize suggested this dominance could be caused by greater aggressiveness and competitiveness of F. meridionale on maize. We evaluated pathogenicity and toxigenicity of 16 isolates of F. graminea ...
DOI:
10.1094/PHYTO-04-21-0149-R

12. High-performance liquid chromatography for the sensitive zearalenone determination by the automated immunomagnetic beads purifier for one-step sample pre-treatment

Author:
Bo Zhang; Wenting Liu; Zhenjiang Liu; Xiaoling Fu; Daolin Du
Source:
European food research & technology 2022 v.248 no.1 pp. 109-117
ISSN:
1438-2377
Subject:
zearalenone,   etc   ; automation; feeds; food research; high performance liquid chromatography; monoclonal antibodies; technology;     Show all 7 Subjects
Abstract:
... In this study, a sensitive high-performance liquid chromatography method for zearalenone determination in feeds and grains was established based on the automatic immunomagnetic bead purifier analyzer (KY-AMI-I) for the one-step sample pre-treatment. Various parameters that may affect the analytical performance were investigated. Immunomagnetic bead separation system based on a monoclonal antibody ...
DOI:
10.1007/s00217-021-03862-3

13. Microbial and enzymatic battle with food contaminant zearalenone (ZEN)

Author:
Bilal Murtaza; Xiaoyu Li; Liming Dong; Muhammad Tariq Javed; Le Xu; Muhammad Kashif Saleemi; Gen Li; Bowen Jin; Huijing Cui; Ashiq Ali; Lili Wang; Yongping Xu
Source:
Applied microbiology and biotechnology 2022 v.106 no.12 pp. 4353-4365
ISSN:
0175-7598
Subject:
zearalenone,   etc   ; biodegradation; biotechnology; equipment; food contamination; genetic engineering; nutritive value; palatability; yeasts;     Show all 9 Subjects
Abstract:
... Zearalenone (ZEN) contamination of various foods and feeds is an important global problem. In some animals and humans, ZEN causes significant health issues in addition to massive economic losses, annually. Therefore, removal or degradation of the ZEN in foods and feeds is required to be done. The conventional physical and chemical methods have some serious issues including poor efficiency, decreas ...
DOI:
10.1007/s00253-022-12009-7

14. Recent advances in the highly sensitive determination of zearalenone residues in water and environmental resources with electrochemical biosensors

Author:
Hessamaddin Sohrabi; Mir Reza Majidi; Omid Arbabzadeh; Pegah Khaaki; Sajjad Pourmohammad; Alireza Khataee; Yasin Orooji
Source:
Environmental research 2022 v.204 pp. 112082
ISSN:
0013-9351
Subject:
zearalenone,   etc   ; biosensors; carcinogenicity; electrochemistry; estrogens; genotoxicity; graphene; immunotoxicity; mutagenicity; nephrotoxicity; research; teratogenicity;     Show all 12 Subjects
Abstract:
... Zearalenone (ZEN), a significant class of mycotoxin which is considered as a xenoestrogen, permits, similar to natural estrogens, it's binding to the receptors of estrogen resulting in various reproductive diseases especially, hormonal misbalance. ZEN has toxic effects on human and animal health as a result of its teratogenicity, carcinogenicity, mutagenicity, nephrotoxicity, genotoxicity, and imm ...
DOI:
10.1016/j.envres.2021.112082

15. Electrochemical aptasensing strategy based on a multivariate polymertitanium-metal-organic framework for zearalenone analysis

Author:
Fenghe Duan; Feilong Rong; Chuanpan Guo; Kun Chen; Minghua Wang; Zhihong Zhang; Riccardo Pettinari; Liming Zhou; Miao Du
Source:
Food chemistry 2022 v.385 pp. 132654
ISSN:
0308-8146
Subject:
zearalenone,   etc   ; aptasensors; coordination polymers; detection limit; electrochemistry; food chemistry; ligands; nanosheets; oligonucleotides; titanium;     Show all 10 Subjects
Abstract:
... An electrochemical aptasensing strategy was developed with a novel bioplatform based on a multivariate titanium metal–organic framework, i.e. MTV polyMOF(Ti), to detect zearalenone (ZEN). MTV polyMOF(Ti) was prepared by using mixed linkers of polyether polymer (pbdc-xa or L₈, pbdc = poly(1,4-benzenedicarboxylate) and 1,4-benzenedicarboxylic acid (H₂bdc or L₀) as well as tetrabutyl titanate as node ...
DOI:
10.1016/j.foodchem.2022.132654

16. Investigation of the mechanism of zearalenone metabolization in different systems: Electrochemical and theoretical approaches

Author:
Agnieszka Rogowska; Paweł Pomastowski; Małgorzata Szultka-Młyńska; Justyna Walczak-Skierska; Katarzyna Rafińska; Zbigniew Rafiński; Bogusław Buszewski
Source:
Toxicon 2022 v.210 pp. 19-24
ISSN:
0041-0101
Subject:
zearalenone,   etc   ; electrochemistry; electrodes; endocrine system; human cell lines; metabolism; metabolites; quantum mechanics; toxicity;     Show all 9 Subjects
Abstract:
... Mycotoxins are toxic metabolites produced by mold fungi, which commonly contaminate cereal crops. These compounds include zearalenone (ZEA), which may disturb the proper functioning of the endocrine system in mammals. The metabolism of ZEA plays a key role in its toxic properties. The type and amount of produced metabolites may contribute to both the reduction and increase in its pathogenic effect ...
DOI:
10.1016/j.toxicon.2022.02.002

17. Ochratoxin A and zearalenone in poultry feed samples from South China

Author:
Qiongshan Wang; Yarong Zhao; Peirong Chen; Rui Zeng; Yunxiang Liang
Source:
Journal of food safety 2022 v.42 no.1 pp. e12944
ISSN:
0149-6085
Subject:
zearalenone,   etc   ; food safety; liquid chromatography; ochratoxin A; poultry feed; tandem mass spectrometry; China;     Show all 7 Subjects
Abstract:
... Data regarding ochratoxin A (OTA) and zearalenone (ZEA) contamination in feed in South China are limited. Here, we evaluated OTA and ZEA contamination in 514 poultry feed samples collected from South China. We validated a modified QuEChERS (quick, easy, cheap, effective, rugged, and safe) method and the mycotoxins were quantified by high‐pressure liquid chromatography–tandem mass spectrometry. OTA ...
DOI:
10.1111/jfs.12944

18. Microbial detoxification of mycotoxins in food and feed

Author:
Hongwen Xu; Liangzhe Wang; Jiadi Sun; Liping Wang; Hongyan Guo; Yongli Ye; Xiulan Sun
Source:
Critical reviews in food science and nutrition 2022 v.62 no.18 pp. 4951-4969
ISSN:
1549-7852
Subject:
zearalenone,   etc   ; aflatoxins; carcinogenicity; deoxynivalenol; food science; fumonisins; hepatotoxicity; metabolites; mutagenicity; nephrotoxicity; nutrition; ochratoxins; pollution;     Show all 13 Subjects
Abstract:
... Mycotoxins are metabolites produced by fungi growing in food or feed, which can produce toxic effects and seriously threaten the health of humans and animals. Mycotoxins are commonly found in food and feed, and are of significant concern due to their hepatotoxicity, nephrotoxicity, carcinogenicity, mutagenicity, and ability to damage the immune and reproductive systems. Traditional physical and ch ...
DOI:
10.1080/10408398.2021.1879730

19. Prussian blue immunochromatography with portable smartphone-based detection device for zearalenone in cereals

Author:
Zhiwei Liu; Qicheng Hua; Jin Wang; Zaoqing Liang; Zexuan Zhou; Xing Shen; Hongtao Lei; Xiangmei Li
Source:
Food chemistry 2022 v.369 pp. 131008
ISSN:
0308-8146
Subject:
zearalenone,   etc   ; antibodies; antigens; bioactive properties; corn; detection limit; food chemistry; immunoaffinity chromatography; quantitative analysis; wheat;     Show all 10 Subjects
Abstract:
... In this study, we developed a prussian blue nanoparticles (PBNPs) immunochromatographic assay (ICA) integrated with smartphone-based detection device for ZEN in cereals. PBNPs, as probe labels, were synthesized with properties of controllable structure, environment friendliness, and high affinities to antibody (Ab). PBNPs-ICA quantitative analysis was performed with a hand-held smartphone-based de ...
DOI:
10.1016/j.foodchem.2021.131008

20. Radioiodination of zearalenone and determination of Lactobacillus plantarum effect of on zearalenone organ distribution: In silico study and preclinical evaluation

Author:
M.H. Sanad; A.B. Farag; Sabry A. Bassem; F.A. Marzook
Source:
Toxicology reports 2022 v.9 pp. 470-479
ISSN:
2214-7500
Subject:
zearalenone,   etc   ; Lactobacillus plantarum; bioavailability; caudal vein; computer simulation; intestines; lactic acid; liver; protective effect; toxicology;     Show all 10 Subjects
Abstract:
... Zearalenone (ZEN) which is one of the known fusarium species mycotoxin, produced primarily on many cereal crops. Consequently, the current study aims to estimate the possibility of labeling zearalenone and the pattern of accumulation of the produced labeled zearalenone [¹²⁵I]-ZEN in different mice tissues, and the possible protective effect of Lactobacillus plantarum to reduce organ accumulation o ...
DOI:
10.1016/j.toxrep.2022.02.003