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- Jørgensen, Jens Noesgaard, et al. Show all 5 Authors
- Animal feed science and technology 2016 v.221 pp. 54-61
- Bacillus licheniformis; Bacillus subtilis; adverse effects; body weight; calcium; dietary supplements; digestibility; energy; energy density; females; growth performance; males; phosphorus; piglets; probiotics; slaughter; spray drying; swine feeding; weaning
- ... The study was conducted to determine the effects of a Bacillus-based probiotic (mixture of spray-dried spore-forming Bacillus licheniformis (DSM 5749) and Bacillus subtilis (DSM 5750)) supplementation and different diet energy densities on growth performance and nutrient digestibility in wean-to-finish pigs. A total of 576 weaned piglets with initial body weight (BW) of 7.1±1.1kg were used. Pigs w ...
- Noesgaard, Daniel, et al. Show all 21 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2014 v.111 no.3 pp. 1055-1059
- GATA transcription factors; T-lymphocytes; animal models; autoimmune diseases; clinical trials; drinking water; gene expression; genes; immunomodulation; immunomodulators; insulin; insulin-dependent diabetes mellitus; interleukin-12; interleukin-1beta; interleukin-6; islets of Langerhans; lysine; macrophages; mechanism of action; messenger RNA; mice; mitogen-activated protein kinase; patients; phosphorylation; transcription factor NF-kappa B; tumor necrosis factor-alpha; weaning
- ... Type 1 diabetes is due to destruction of pancreatic β-cells. Lysine deacetylase inhibitors (KDACi) protect β-cells from inflammatory destruction in vitro and are promising immunomodulators. Here we demonstrate that the clinically well-tolerated KDACi vorinostat and givinostat revert diabetes in the nonobese diabetic (NOD) mouse model of type 1 diabetes and counteract inflammatory target cell damag ...
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