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1. A balanced game: chicken macrophage response to ALV-J infection

Author:
Feng, Min; Xie, Tingting; Li, Yuanfang; Zhang, Nan; Lu, Qiuyuan; Zhou, Yaohong; Shi, Meiqing; Sun, Jingchen; Zhang, Xiquan
Source:
Veterinary research 2019 v.50 no.1 pp. 20
ISSN:
1297-9716
Subject:
Avian leukosis virus; Western blotting; carrier state; chemokine CCL20; chickens; gene expression regulation; gene ontology; genes; immunosuppression; inducible nitric oxide synthase; innate immunity; interleukin-1beta; lysozyme; macrophages; neoplasms; pathogens; reverse transcriptase polymerase chain reaction; transcriptomics
Abstract:
... Avian leukosis virus subgroup J (ALV-J) infection can cause tumors and immunosuppression in infected chickens. Macrophages play a central role in host defense against invading pathogens. In this study, we discovered an interesting phenomenon: ALV-J replication is weakened from 3 hours post-infection (hpi) to 36 hpi, which was verified using Western blotting and RT-PCR. To further investigate the i ...
DOI:
10.1186/s13567-019-0638-y

2. Abdominal volume computed tomography assessment of body composition in dogs

Author:
Turner, R. B. S.; Hepworth, G.; Wilson, K.; Tyrrell, D.; Dunshea, F. R.; Mansfield, C. S.
Source:
BMC veterinary research 2019 v.15 no.1 pp. 21
ISSN:
1746-6148
Subject:
abdominal fat; computed tomography; dogs; dual-energy X-ray absorptiometry; mineral content; tissue distribution
Abstract:
... BACKGROUND: Computed tomography (CT) has been used to estimate body composition and determine tissue distribution in dogs, despite limited validation. This may introduce error into estimates of body composition studies and its effect on health in dogs. Further, the modality has not been validated against dual-energy X-ray absorptiometry (DXA) or over a wide range of dog breeds, ages and sexes. The ...
DOI:
10.1186/s12917-018-1768-6

3. Absence of herb-drug interactions of mistletoe with the tamoxifen metabolite (E/Z)-endoxifen and cytochrome P450 3A4/5 and 2D6 in vitro

Author:
Weissenstein, U.; Kunz, M.; Oufir, M.; Wang, J. T.; Hamburger, M.; Urech, K.; Regueiro, U.; Baumgartner, S.
Source:
BMC complementary and alternative medicine 2019 v.19 no.1 pp. 23
ISSN:
1472-6882
Subject:
Viscum album; adverse effects; alternative medicine; apoptosis; breast neoplasms; cell cycle; cytochrome P-450; cytotoxicity; estradiol; estrogen receptors; gender; human cell lines; humans; in vitro studies; liver microsomes; metabolism; metabolites; neoplasm cells; patients; risk; tamoxifen; women
Abstract:
... BACKGROUND: Women diagnosed with breast cancer frequently seek complementary and alternative (CAM) treatment options that can help to cope with their disease and the side effects of conventional cancer therapy. Especially in Europe, breast cancer patients use herbal products containing mistletoe (Viscum album L.). The oldest and one of the most prescribed conventional drugs for the treatment of es ...
DOI:
10.1186/s12906-019-2439-2

4. Accuracy assessment of plant height using an unmanned aerial vehicle for quantitative genomic analysis in bread wheat

Author:
Hassan, Muhammad Adeel; Yang, Mengjiao; Fu, Luping; Rasheed, Awais; Zheng, Bangyou; Xia, Xianchun; Xiao, Yonggui; He, Zhonghu
Source:
Plant methods 2019 v.15 no.1 pp. 37
ISSN:
1746-4811
Subject:
breeding; breeding programs; chromosomes; cost effectiveness; data collection; genomics; heritability; lodging resistance; models; phenotype; phenotypic variation; plant growth; plant height; prediction; quantitative trait loci; time series analysis; unmanned aerial vehicles; wheat
Abstract:
... BACKGROUND: Plant height is an important selection target since it is associated with yield potential, stability and particularly with lodging resistance in various environments. Rapid and cost-effective estimation of plant height from airborne devices using a digital surface model can be integrated with academic research and practical wheat breeding programs. A bi-parental wheat population consis ...
DOI:
10.1186/s13007-019-0419-7

5. Accuracy of imputation to whole-genome sequence in sheep

Author:
Bolormaa, Sunduimijid; Chamberlain, Amanda J.; Khansefid, Majid; Stothard, Paul; Swan, Andrew A.; Mason, Brett; Prowse-Wilkins, Claire P.; Duijvesteijn, Naomi; Moghaddar, Nasir; van der Werf, Julius H.; Daetwyler, Hans D.; MacLeod, Iona M.
Source:
Genetics, selection, evolution 2019 v.51 no.1 pp. 1
ISSN:
1297-9686
Subject:
Border Leicester; Merino; alleles; chromosomes; computer software; genomics; genotype; genotyping; heritability; prediction; sheep; single nucleotide polymorphism
Abstract:
... BACKGROUND: The use of whole-genome sequence (WGS) data for genomic prediction and association studies is highly desirable because the causal mutations should be present in the data. The sequencing of 935 sheep from a range of breeds provides the opportunity to impute sheep genotyped with single nucleotide polymorphism (SNP) arrays to WGS. This study evaluated the accuracy of imputation from SNP g ...
DOI:
10.1186/s12711-018-0443-5

6. Accurate prediction of cell type-specific transcription factor binding

Author:
Keilwagen, Jens; Posch, Stefan; Grau, Jan
Source:
Genome biology 2019 v.20 no.1 pp. 9
ISSN:
1474-760X
Subject:
animal tissues; binding sites; chromatin; genomics; prediction; transcription factors
Abstract:
... Prediction of cell type-specific, in vivo transcription factor binding sites is one of the central challenges in regulatory genomics. Here, we present our approach that earned a shared first rank in the “ENCODE-DREAM in vivo Transcription Factor Binding Site Prediction Challenge” in 2017. In post-challenge analyses, we benchmark the influence of different feature sets and find that chromatin acces ...
DOI:
10.1186/s13059-018-1614-y

7. A chemical screen identifies two novel small compounds that alter Arabidopsis thaliana pollen tube growth

Author:
Laggoun, Ferdousse; Dardelle, Flavien; Dehors, Jérémy; Falconet, Denis; Driouich, Azeddine; Rochais, Christophe; Dallemagne, Patrick; Lehner, Arnaud; Mollet, Jean-Claude
Source:
BMC plant biology 2019 v.19 no.1 pp. 152
ISSN:
1471-2229
Subject:
Arabidopsis thaliana; cell walls; dose response; enzymes; females; microfilaments; models; ovules; phenotype; pollen; pollen tubes; seeds; sexual reproduction; spermatozoa; stigma; tobacco; tomatoes
Abstract:
... BACKGROUND: During sexual reproduction, pollen grains land on the stigma, rehydrate and produce pollen tubes that grow through the female transmitting-tract tissue allowing the delivery of the two sperm cells to the ovule and the production of healthy seeds. Because pollen tubes are single cells that expand by tip-polarized growth, they represent a good model to study the growth dynamics, cell wal ...
DOI:
10.1186/s12870-019-1743-9

8. A closer look at the relationship among accelerometer-based physical activity metrics: ICAD pooled data

Author:
Kwon, Soyang; Andersen, Lars Bo; Grøntved, Anders; Kolle, Elin; Cardon, Greet; Davey, Rachel; Kriemler, Susi; Northstone, Kate; Page, Angie S.; Puder, Jardena J.; Reilly, John J.; Sardinha, Luis B.; van Sluijs, Esther M. F.; Janz, Kathleen F.
Source:
The international journal of behavioral nutrition and physical activity 2019 v.16 no.1 pp. 40
ISSN:
1479-5868
Subject:
accelerometers; children; databases; health effects assessments; light intensity; physical activity; sedentary lifestyle; statistical models
Abstract:
... BACKGROUND: Accelerometers are widely used to assess child physical activity (PA) levels. Using the accelerometer data, several PA metrics can be estimated. Knowledge about the relationships between these different metrics can improve our understanding of children’s PA behavioral patterns. It also has significant implications for comparing PA metrics across studies and fitting a statistical model ...
DOI:
10.1186/s12966-019-0801-x

9. A combination of approaches evidenced seed storage behaviour in the miracle berry Synsepalum dulcificum (Schumach. et Thonn.) Daniell

Author:
Tchokponhoué, Dèdéou Apocalypse; N’Danikou, Sognigbé; Achigan-Dako, Enoch Gbènato
Source:
BMC plant biology 2019 v.19 no.1 pp. 117
ISSN:
1471-2229
Subject:
Synsepalum dulcificum; breeding programs; cold; cold storage; conservation practices; endangered species; germination; models; planning; plant genetic resources; probability; seed moisture; seed storage; seedling growth; seedlings; seeds; shelf life; storage temperature; storage time; viability; vigor; water content
Abstract:
... BACKGROUND: Knowledge on seed storage behaviour is crucial for planning conservation strategies of plant genetic resources particularly in economically promising but endangered species like Synsepalum dulcificum, viewed as recalcitrant-seeded species albeit sound evidence was lacking. In this study, we combined an experimental approach based on critical moisture content and storage environment ana ...
DOI:
10.1186/s12870-019-1714-1

10. A combination of climatic conditions determines major within-season dengue outbreaks in Guangdong Province, China

Author:
Wang, Xia; Tang, Sanyi; Wu, Jianhong; Xiao, Yanni; Cheke, Robert A.
Source:
Parasites & vectors 2019 v.12 no.1 pp. 45
ISSN:
1756-3305
Subject:
climatic factors; dengue; humans; imagos; models; prediction; rain; reproduction; temperature; China
Abstract:
... BACKGROUND: China’s Guangdong Province experienced a major dengue outbreak in 2014. Here we investigate if the weather conditions contributing to the outbreak can be elucidated by multi-scale models. METHODS: A multi-scale modelling framework, parameterized by available weather, vector and human case data, was used to examine the integrative effect of temperature and precipitation variation on the ...
DOI:
10.1186/s13071-019-3295-0

11. A comparative evaluation of hybrid error correction methods for error-prone long reads

Author:
Fu, Shuhua; Wang, Anqi; Au, Kin Fai
Source:
Genome biology 2019 v.20 no.1 pp. 26
ISSN:
1474-760X
Subject:
data quality; genomics; guidelines; haplotypes; nucleotide sequences; sequence analysis
Abstract:
... BACKGROUND: Third-generation sequencing technologies have advanced the progress of the biological research by generating reads that are substantially longer than second-generation sequencing technologies. However, their notorious high error rate impedes straightforward data analysis and limits their application. A handful of error correction methods for these error-prone long reads have been devel ...
DOI:
10.1186/s13059-018-1605-z

12. A comparison of log Kow (n-octanol–water partition coefficient) values for non-ionic, anionic, cationic and amphoteric surfactants determined using predictions and experimental methods

Author:
Hodges, Geoff; Eadsforth, Charles; Bossuyt, Bart; Bouvy, Alain; Enrici, Marie-Helene; Geurts, Marc; Kotthoff, Matthias; Michie, Eleanor; Miller, Dennis; Müller, Josef; Oetter, Gunter; Roberts, Jayne; Schowanek, Diederik; Sun, Ping; Venzmer, Joachim
Source:
Environmental sciences Europe 2019 v.31 no.1 pp. 1
ISSN:
2190-4707
Subject:
bioavailability; environmental assessment; environmental fate; high performance liquid chromatography; ionization; models; nonionic surfactants; prediction; products and commodities; risk assessment; toxicity; water solubility; weight-of-evidence
Abstract:
... BACKGROUND: Surfactants are widely used across the globe both in industrial and consumer products. The n-octanol/water partition ratio or coefficient (log Kₒw) and n-octanol/water distribution coefficient (log D) are key parameters in environmental risk assessment of chemicals as they are often used to estimate the environmental fate and bioavailability and thus exposure and toxicity of a compound ...
DOI:
10.1186/s12302-018-0176-7

13. A contribution towards improving the applicability of the Myriophyllum aquaticum sediment contact test

Author:
Tomić, Tanja; Mihajlović, Varja; Jurca, Tamara; Tubić, Aleksandra; Krčmar, Dejan; Tričković, Jelena; Teodorović, Ivana
Source:
Environmental sciences Europe 2019 v.31 no.1 pp. 20
ISSN:
2190-4707
Subject:
Myriophyllum aquaticum; chemical analysis; clay fraction; freshwater; macrophytes; monitoring; organic matter; particle size distribution; physicochemical properties; plant growth; pollutants; root systems; roots; sand; shoots; toxicity; water quality
Abstract:
... BACKGROUND: Whole sediment contact tests provide realistic exposure scenarios, but the inherent properties of sediments may play a significant role in organism’s response and interfere with result interpretation. Recently, a sediment contact test with a rooted aquatic macrophyte Myriophyllum aquaticum has been standardized. The present study aims to distinguish between effects of basic sediment pr ...
DOI:
10.1186/s12302-019-0200-6

14. A critical integrative review of complementary medicine education research: key issues and empirical gaps

Author:
Gray, Alastair C.; Steel, Amie; Adams, Jon
Source:
BMC complementary and alternative medicine 2019 v.19 no.1 pp. 73
ISSN:
1472-6882
Subject:
alternative medicine; educational institutions; educational research; educational technology; electronic learning; empirical research; health education; health services; labor force; researchers; tertiary sector
Abstract:
... BACKGROUND: Complementary Medicine (CM) continues to thrive across many countries. Closely related to the continuing popularity of CM has been an increased number of enrolments at CM education institutions across the public and private tertiary sectors. Despite the popularity of CM across the globe and growth in CM education/education providers, to date, there has been no critical review of peer-r ...
DOI:
10.1186/s12906-019-2466-z

15. A cross-sectional screening by next-generation sequencing reveals Rickettsia, Coxiella, Francisella, Borrelia, Babesia, Theileria and Hemolivia species in ticks from Anatolia

Author:
Brinkmann, Annika; Hekimoğlu, Olcay; Dinçer, Ender; Hagedorn, Peter; Nitsche, Andreas; Ergünay, Koray
Source:
Parasites & vectors 2019 v.12 no.1 pp. 26
ISSN:
1756-3305
Subject:
Babesia ovis; Borrelia; Coxiella; Francisella; Haemaphysalis; Hyalomma marginatum; Protozoa; Rhipicephalus bursa; Rhipicephalus sanguineus; Rickettsia; Theileria; avirulent strains; bacteria; disease transmission; disease vectors; domestic animals; endosymbionts; genes; high-throughput nucleotide sequencing; hosts; humans; metagenomics; mixed infection; nucleotide sequences; pathogenicity; phylogeny; plasmids; ribosomal RNA; screening; tick-borne diseases; ticks; Turkey (country)
Abstract:
... BACKGROUND: Ticks participate as arthropod vectors in the transmission of pathogenic microorganisms to humans. Several tick-borne infections have reemerged, along with newly described agents of unexplored pathogenicity. In an attempt to expand current information on tick-associated bacteria and protozoans, we performed a cross-sectional screening of ticks, using next-generation sequencing. Ticks s ...
DOI:
10.1186/s13071-018-3277-7

16. A cross-sectional study of suckling calves’ passive immunity and associations with management routines to ensure colostrum intake on organic dairy farms

Author:
Johnsen, Julie Føske; Viljugrein, Hildegunn; Bøe, Knut Egil; Gulliksen, Stine Margrethe; Beaver, Annabelle; Grøndahl, Ann Margaret; Sivertsen, Tore; Mejdell, Cecilie Marie
Source:
Acta veterinaria scandinavica 2019 v.61 no.1 pp. 7
ISSN:
1751-0147
Subject:
blood sampling; blood serum; colostrum; cows; cross-sectional studies; dairy calves; dairy farming; farms; herds; immunoglobulin G; passive immunity; spring; suckling; udders; winter
Abstract:
... BACKGROUND: For suckling dairy calves, different management routines to ensure sufficient colostrum intake are applied: visual assessment, hand feeding supplemental colostrum or assistance. However, knowledge on the efficacy of these methods to prevent failure of passive transfer [FPT: serum immunoglobulin (IgG) < 10 g/L] is lacking. Our objectives were to explore FPT prevalence in suckling dairy ...
DOI:
10.1186/s13028-019-0442-8

17. 14-3-3ε acts as a proviral factor in highly pathogenic porcine reproductive and respiratory syndrome virus infection

Author:
Cao, Shengliang; Cong, Fangyuan; Tan, Min; Ding, Guofei; Liu, Jiaqi; Li, Li; Zhao, Yuzhong; Liu, Sidang; Xiao, Yihong
Source:
Veterinary research 2019 v.50 no.1 pp. 16
ISSN:
1297-9716
Subject:
Porcine reproductive and respiratory syndrome virus; macrophages; porcine reproductive and respiratory syndrome; small interfering RNA; swine; therapeutics; vaccines; viral nonstructural proteins; China
Abstract:
... The highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) emerged in 2006 in China and caused great economic losses for the swine industry because of the lack of an effective vaccine. 14-3-3 proteins are generating significant interest as potential drug targets by allowing the targeting of specific pathways to elicit therapeutic effects in human diseases. In a previous s ...
DOI:
10.1186/s13567-019-0636-0

18. Acupuncture in improving endometrial receptivity: a systematic review and meta-analysis

Author:
Zhong, Yajing; Zeng, Fanzhu; Liu, Wanjun; Ma, Jing; Guan, Yongge; Song, Yang
Source:
BMC complementary and alternative medicine 2019 v.19 no.1 pp. 61
ISSN:
1472-6882
Subject:
acupuncture; blood; confidence interval; databases; drug therapy; embryo transfer; endometrium; meta-analysis; physical therapy; pregnancy rate; randomized clinical trials; relative risk; systematic review; women
Abstract:
... BACKGROUND: This systematic review aimed at summarizing and evaluating the evidence of randomized controlled trials (RCTs) using acupuncture to improve endometrial receptivity (ER). METHODS: We searched 12 databases electronically through August 2018 without language restrictions. We included RCTs of women of infertility due to low ER, and excluded infertility caused by other reasons or non-RCTs. ...
DOI:
10.1186/s12906-019-2472-1

19. Acute kidney injury management using intermittent low efficiency haemodiafiltration in a critical care unit: 39 dogs (2012–2015)

Author:
Cambournac, Maxime; Goy-Thollot, Isabelle; Guillaumin, Julien; Ayoub, Jean-Yves; Pouzot-Nevoret, Céline; Barthélemy, Anthony; Bonnet-Garin, Jeanne-Marie
Source:
Acta veterinaria scandinavica 2019 v.61 no.1 pp. 17
ISSN:
1751-0147
Subject:
blood serum; creatinine; death; dogs; euthanasia; hemodialysis; kidneys; leptospirosis; males; nephrotoxins; odds ratio; pathogens; potassium; prospective studies; survival rate; urine; France; North America
Abstract:
... BACKGROUND: Veterinary studies describing acute kidney injury (AKI) management using renal replacement therapy (RRT) are limited and have primarily focused on intermittent haemodialysis in North American populations. European data are lacking, although differences in populations, pathogen and toxin exposure and RRT modalities may exist between Europe and North America. The present study reviewed R ...
DOI:
10.1186/s13028-019-0452-6

20. Acute liver failure associated with Fructus Psoraleae: a case report and literature review

Author:
Li, Ang; Gao, Minhong; Zhao, Na; Li, Ping; Zhu, Jinguo; Li, Wenfei
Source:
BMC complementary and alternative medicine 2019 v.19 no.1 pp. 84
ISSN:
1472-6882
Subject:
Cullen corylifolium; adverse effects; alternative medicine; case studies; hepatitis; hepatotoxicity; herbs; ingredients; liver; liver failure; patients; physicians; sclera; skin diseases; staining; women
Abstract:
... BACKGROUND: Fructus Psoraleae is the seed of Psoralea corylifolia Linn. Fructus Psoraleae has been shown to be effective in treating some skin diseases, such as vitiligo. As a main ingredient in five types of herbs in the Qubaibabuqi tablet formula, Fructus Psoraleae plays an important role in the treatment of vitiligo. Fructus Psoraleae has potential hepatotoxicity, thus Qubaibabuqi tablets also ...
DOI:
10.1186/s12906-019-2493-9