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A new regio- and stereoselective synthesis of β-enamino ketones with 3-ethoxycyclobutanones and substituted amines
- Liu, Pengfei, Shan, Gang, Chen, Shi, Rao, Yu
- Tetrahedron letters 2012 v.53 no.8 pp. 936-939
- amines, chemical reactions, chemical structure, ketones, methodology, temperature
- A new method toward regio- and stereoselective synthesis of β-enamino ketones is described. Through Lewis acid-catalyzed reactions between 3-ethoxycyclobutanones and substituted amines, a variety of cis and trans β-enamino ketone derivatives were prepared with complete regio- and stereoselectivity at room temperature.