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Simple and efficient synthetic routes to d-cycloserine

Author:
Kim, Hee-Kwon, Park, Kyoung-Joo Jenny
Source:
Tetrahedron letters 2012 v.53 no.13 pp. 1668-1670
ISSN:
0040-4039
Subject:
chemical reactions, chemical structure, organic compounds
Abstract:
d-Cycloserine has been successfully synthesized in good yields through three new synthetic routes from a readily available d-serine. In each synthesis, cyclization served as the key step, and two of the routes employed one-pot operations for the preparation of the target product. These methods featured the use of mild reaction conditions and simple treatments.
Agid:
1099098