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Two new acetylated flavonoid glycosides from Centaurium spicatum L
- Allam, Ahmed E., El-Shanawany, Mohamed A., Backheet, Enaam Y., Nafady, Alaa M., Takano, Fumihide, Ohta, Tomihisa
- Natural medicines 2012 v.66 no.2 pp. 388-393
- Schenkia spicata, glycosides, nuclear magnetic resonance spectroscopy, quercetin
- Two new acetylated flavonol glycosides, quercetin 3-O-[(2,4-diacetyl-α-L: -rhamnopyranosyl)-(1→6)]-2,4-diacetyl-β-D: -galactopyranoside (1) and quercetin 3-O-[(2,4-diacetyl-α-L: -rhamnopyranosyl)-(1→6)]-3,4-diacetyl-β-D: -galactopyranoside (2), in addition to two known acetylated quercetin glycosides quercetin 3-O-[(2,3,4-triacetyl-α-L: -rhamnopyranosyl)-(1→6)-β-D: -galactopyranoside (3) and quercetin 3-O-[(2,3,4-triacetyl-α-L: -rhamnopyranosyl)-(1→6)-3-acetyl-β-D: -galactopyranoside (4), were isolated from the aerial part of Centaurium spicatum (L.) Fritsch (Gentianaceae). Structure elucidation, especially the localization of the acetyl groups, and complete 1H and 13C NMR assignments of these biologically active compounds were carried out using one- and two-dimensional NMR measurements, including 1H- and 13C-NMR, DEPT-135, H–H COSY, HMQC and HMBC, in addition to HR-FAB/MS experiments.