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A Retrospective Study of Feline Gastric Lymphoma in 16 Chemotherapy-Treated Cats

Gustafson, Tanya L., Villamil, Armando, Taylor, Bonnie E., Flory, Andrea
Journal of the American Animal Hospital Association 2014 v.50 no.1 pp. 46-52
cat diseases, cats, drug therapy, females, lymphoma, males, remission, retrospective studies, spaying, steroids, stomach neoplasms
The purposes of this study were to describe cases of feline gastric lymphoma with regards to signalment, clinical presentation, laboratory and ancillary study findings, response to therapy, and outcomes and to identify prognostic variables. Sixteen cats with stage I and II gastric lymphoma treated with chemotherapy were included in this study. Seventy-five percent of cats experienced remission. Overall, first remission duration was 108 days. Response to treatment was prognostic as in other types of feline lymphoma. Cats with a complete remission (CR) had longer survival times compared with cats with a partial remission (PR). Sex and treatment with a rescue protocol were found to be prognostic with castrated males having longer survivals than spayed females. Cats that received rescue chemotherapy had shorter first remission durations than those that did not. Prior treatment with steroids and stage were not found to be significant prognostic variables. This study characterizes gastric lymphoma treated with chemotherapy in cats. Further studies are needed to determine the comparative efficacy of surgical and chemotherapeutic treatments for feline gastric lymphoma.