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Plasma amino acids and sports injuries

Author:
van den Baar, M. T. M., Fekkes, D., van den Hoogenband, C. R., Duivenvoorden, H. J., Pepplinkhuizen, L.
Source:
Amino acids 2004 v.26 no.1 pp. 71-76
ISSN:
0939-4451
Subject:
glycine (amino acid), lysine, ornithine, sports, taurine, tryptophan, tyrosine
Abstract:
The aim of this study was to explore the relationship between changes in plasma amino acids and the incidence of sports injuries during a soccer season. Fourteen plasma amino acids were assayed at monthly intervals in 12 young soccer players during a whole soccer season. Based on the number and severity of injuries the soccer players were divided into an injury-prone and a non-injury-prone group. The mean plasma level of the amino acid glycine was significantly lower (P=0.009) in the injury-prone group than the other group, while the mean plasma levels of tyrosine, tryptophan and lysine were higher in the injury-prone group during this period (P<0.05). However there were no significant differences in the calculated plasma tryptophan and tyrosine/large neutral amino acids ratios. Significant linear time trends were observed for taurine, ornithine, lysine and the tryptophan/large neutral amino acids ratio.These results indicate that the plasma concentrations of glycine and to a lesser extent those of tyrosine, tryptophan and lysine may be promising peripheral markers for injury-proneness in young soccer players. Whether a role for glycine substitution will be indicative to reduce the occurrence of sports injuries will need to be investigated in future studies.
Agid:
1210732