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In vitro Antimicrobial and Antioxidant Activity of Vaccinium arctostaphylos L. Extracts

Mahboubi, Mohaddese, Kazempour, Nastaran, Taghizadeh, Mohsen
Journal of Biologically Active Products from Nature 2013 v.3 no.4 pp. 241-247
Vaccinium arctostaphylos, anti-infective properties, antioxidant activity, antioxidants, antiseptics, ethanol, ethyl acetate, flavonoids, fruits, inhibitory concentration 50, leaves, methanol, perennials, urinary tract diseases
V. arctostaphylos or “Qare-Qat” is a perennial plant from Ericaceae family has traditionally used as antiseptic for treatment of some infections such as urinary tract infections. This study evaluate the antimicrobial activity of V. arctostaphylos extracts (aqueous, ethanol, methanol and ethyl acetate) from leaves and fruits and total phenolic and flavonoid content of these extracts and their relation to antioxidant activities. V. arctostaphylos fruits ethyl acetate extract had 164.9 mg GAC/g total phenolic content, the higher total flavonoid content were for leaves ethyl acetate extract (60.1 mg QE/g). The antioxidant evaluation exhibited that the lower IC ₅₀ was related to fruits ethyl acetate extract (15.6 µg/ml), followed by leaves ethanol extract (25 µg/ml), fruits methanol, and leaves ethyl acetate extracts (35 µg/ml). Fruits ethyl acetate extract had lower antimicrobial activity, followed by fruits and leaves aqueous extracts and fruits methanol extract. V. arctostaphylos leaves ethanolic extract showed a broad antimicrobial activity. V. arctostaphylos can be used as antimicrobial and antioxidant agents as traditional uses.