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Meal replacements and fibre supplement as a strategy for weight loss. Proprietary PGX® meal replacement and PGX® fibre supplement in addition to a calorie-restricted diet to achieve weight loss in a clinical setting

Reichert, Ronald G., Reimer, Raylene A., Kacinik, Veronica, Pal, Sebely, Gahler, Roland J., Wood, Simon
Biotechnology & genetic engineering reviews 2013 v.29 no.2 pp. 221-229
biotechnology, body mass index, breakfast, dinner, energy intake, foods, genetic engineering, granules, low calorie diet, lunch, men, menu planning, overweight, snacks, soluble fiber, waist, weight loss, women
Meal replacements and viscous soluble fibre represent safe and sustainable aids for weight loss. Our purpose was to determine if PGX® meal replacements and PGX ® fibre complex in combination with a calorie-restricted diet would aid in weight loss in a clinical setting. Fifty-two overweight and obese participants (49 women, 3 men; average age 47.1 years) with a mean body mass index (BMI) of 33.8 ± 6.4 kg/m ² consumed 57 g of proprietary PGX® meal replacement product at breakfast and another 57 g at lunch for 12 weeks. In addition to the meal replacements, they were also asked to consume 5 g/day of PGX® fibre in the form of granules, powder or capsules together with 250 mlwater. A registered dietician recommended low-fat, low-glycaemic-index foods for snacks and the dinner menus such that each volunteer was consuming a total of 1200 kcal/day. All participants (n = 52) lost a significant amount of weight from baseline (−4.69 ± 3.73 kg), which was further reflected in the reductions in their waist (−7.11 ± 6.35 cm) and hip circumference (−5.59 ± 3.58 cm) over the 12-week study (p < 0.0001). BMI scores (n = 51) were reduced by 1.6 ± 1.4 kg/m ². The use of PGX® meal replacements and PGX ® fibre along with a controlled dietary caloric intake is of benefit for short-term weight loss.