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A percutaneous liver biopsy technique in ducks (Anas platyrhynchos) experimentally infected with duck hepatitis B virus

Author:
Varagona, G., Ellis, L. A., Moore, D., Penney, D., Dusheiko, G. M.
Source:
Laboratory animals 1991 v.25 no.3 pp. 254-257
ISSN:
1758-1117
Subject:
ducks, liver, biopsy, disease models
Abstract:
Aylesbury ducks (Anas platyrhynchos) chronically infected with the duck hepatitis B virus provide a useful model for studying hepadnavirus infection, replication and the effects of antiviral therapy. In these studies, it is necessary to have an effective method for obtaining repeat liver specimens for histological and molecular analyses. We have therefore developed a percutaneous liver biopsy technique which has a low rate of complications, can be performed at repeated intervals, and provides sufficient quantities of liver tissue for histological and nucleic acid hybridization analysis.
Agid:
1388069