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Metal-catalyzed oxidation of ascorbate, deoxyribose and linoleic acid as affected by phytic acid in a model system
- Lee, B.J., Hendricks, D.G.
- Journal of food science 1997 v.62 no.5 pp. 935-984
- ascorbic acid, antioxidants, lipid peroxidation
- Antioxidant activity of phytate was investigated in metal-catalyzed model systems. In a dose-dependent manner, phytate facilitated oxidation of Fe (II) to Fe (III) and inhibited formation of thiobarbituric acid-reactive substances (TBARS) from Fe (II)- or hemeprotein-catalyzed deoxyribose degradation. In the presence of 100 micromolar Fe (III), phytate inhibited reduction of Fe (III) to Fe (II) by 100 micromolar ascorbic acid and it consequently inhibited ascorbate oxidation. Phytate inhibited hemeprotein- and H2O2-catalyzed TBARS formation from linoleic acid micelles. Inhibition by phytate of iron + ascorbate-dependent lipid peroxidation depended on the concentration of ascorbate. These results indicate that phytate may be a useful antioxidant in the protection against oxidative deterioration of foods.