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Sterol dependent growth and ethanol tolerance of a sterol-auxotrophic erg9::HIS3 mutant of Saccharomyces cerevisiae

Author:
Novotny, C., Karst, F.
Source:
Biotechnology letters 1994 v.16 no.5 pp. 539-542
ISSN:
0141-5492
Subject:
Saccharomyces cerevisiae, ergosterol, cholesterol, ethanol, fermentation, mortality, mutants, biomass production
Abstract:
A 3-fold rise in the ergosterol level of growing and stationary cells of the erg9::HIS3 Saccharomyces cerevisiae mutant grown at various concentrations of ergosterol resulted in a higher ethanol tolerance measured as the survival rate at 5 or 15% (V/V) ethanol. A similar protective effect was observed with cholesterol.
Agid:
1412676