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Physical mapping of CSF2RA, ANT3 and STS on the pseudoautosomal region of bovine chromosome X
- Moore, S.S., Byrne, K., Johnson, S.E., Kata, S., Womack, J.E.
- Animal genetics 2001 v.32 no.2 pp. 102-104
- cattle, chromosome mapping, genes, genetic markers, microsatellite repeats, linkage (genetics), nucleic acid hybridization
- The pseudoautosomal region (PAR) of bovine chromosome X (BTA X) has a particularly low representation of genes and markers, making comparative gene mapping in this region difficult. We describe the localization of three genes, colony-stimulating factor 2 receptor alpha (CSF2RA), ADP/ATP translocase 3 (ANT3) and steroid sulphatase (STS) on PAR of BTA X using a 5000 rad whole-genome radiation hybrid panel. The relationship of these genes to a number of previously mapped simple sequence repeat (microsatellite) markers is determined by physical and radiation hybrid mapping methods. The resulting radiation hybrid map resolves a discrepancy between the two major bovine linkage maps in the PAR of BTA X.