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Glycine-Rich Antifreeze Proteins from Snow Fleas
- Graham, Laurie A., Davies, Peter L.
- Science 2005 v.310 no.5747 pp. 461
- Hypogastrura, insect proteins, cold tolerance, amino acid sequences
- We purified antifreeze proteins from winter-active snow fleas, Hypogastrura harveyi. These 6.5- and 15.7-kilodalton thermolabile proteins are glycine-rich (45% of the residues), and the short isoform is composed of the tripeptide repeat Gly-X-X. This makes them very different from other antifreeze proteins, including two from insects, suggesting independent adaptation to freezing environments.