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A review on biological control and metabolism of aflatoxin

Mishra, H.N., Das, C.
Critical reviews in food science and nutrition 2003 v.43 no.3 pp. 245-264
aflatoxins, biological control, bacterial adhesion, biodegradation, enzymes, detoxification (processing), food contamination, intestinal absorption, food safety, fungal diseases of plants, disease prevention, on-farm food safety, chemical structure, plant cultural practices, plant breeding, genetic engineering, probiotics, microbial competition, metabolism, diet, antioxidants
The series of events that led to the discovery of aflatoxin as a potent carcinogen, its biosynthesis, mechanism of action, structure-function relationship provide interesting insight into the economical and technological factors involved in the development of an effective control measure for the toxin. Scientists all over the world are making continuous efforts to explore a generalized process of detoxification, which can bring down the toxin content in heterogenous commodities to a threshold level. In this article biological control methods with special emphasis on in vivo and in vitro enzymatic detoxification of aflatoxin have been reviewed. Future areas of research involving large-scale enzymatic detoxification and modified atmosphere storage are also discussed.