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Presence of IgA-producing cells in rats and mice in relation to microbial status
- Mullink, J. W. M. A., Morsink, F. H. M.
- Laboratory animals 1984 v.18 no.3 pp. 252-257
- viruses, bacteria, rats, mice, immunoglobulins, germ-free animals, specific pathogen-free animals
- The numbers of IgA-producing cells in intestinal mucosa, mesenteric lymph nodes, lungs and bronchial lymph nodes were scored in rats and mice. A statistically significant difference in the scores existed between germ-free and SPF mice and between gnotobiotic and SPF rats. In a group of SPF rats a statistically significant difference in the scores was demonstrated in relation to several bacterial and viral agents.