U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

New combination for the therapy of canine otitis externa I Microbiology of otitis externa

Author:
G. Kiss, Sz. Radványi, G. Szigeti
Source:
journal of small animal practice 1997 v.38 no.2 pp. 51-56
ISSN:
0022-4510
Subject:
antibiotics, dogs, combination drug therapy, antifungal agents, otitis externa, Malassezia pachydermatis, incidence, bacteria, drug resistance
Abstract:
In order to compound a new drug comblnatlon agalnst canlne otitis externa (OE), 515 dogs affected wlth OE were subjected to physical examlnatlon and mlcroblologlcal analysis of their ear exudates. OE was erythematous‐cerumlnous In 83 per cent and suppurative In 17 per cent of the patlent material. Erythematous‐cerumlnous lnflammatlons were characterlsed by severe prurltus and accumulatlon of brownlsh, greasy cerumen In the audltory canal. The yeast Malassezla jmchydermat/s was Isolated from the ears of 76 per cent of the dogs, often In comblnatlon wlth Staphylococcus lntermedlus bacterla. M pachydermatls showed the most sensltlvlty, In decreasing order of efflcacy, to ketoconazole, econazole, clotrlmazole, mlconazole and nystatln. S lntermedlus Isolates were most sensltlve to amoxyclllln‐clavulanlc acld, enrofloxacln, cephalexln and gentamlcln. The mlcroorganlsm most frequently Isolatcbd from dogs wlth suppurative OE was Pseudomonas aewglnosa; In some cases Proteus, Streptococcus and Pasteurella were also Isolated. The P aeruglnosa Isolates showed the highest sensltlvlty to gentamlcln, polymyxln B and tobramycln.
Agid:
1519619