Jump to Main Content
CYCLIN-DEPENDENT KINASE8 Differentially Regulates Plant Immunity to Fungal Pathogens through Kinase-Dependent and -Independent Functions in Arabidopsis
- Zhu, Yingfang, Schluttenhoffer, Craig M., Wang, Pengcheng, Fu, Fuyou, Thimmapuram, Jyothi, Zhu, Jian-Kang, Lee, Sang Yeol, Yun, Dae-Jin, Mengiste, Tesfaye
- The plant cell 2014 v.26 no.10 pp. 4149-4170
- Arabidopsis, fungi, gene expression, immune response, pathogens, transcription factors
- This work explores the intriguing roles of Mediator subunit CYCLIN-DEPENDENT KINASE8 (CDK8) in plant immune responses to fungal infection. CDK8 regulates jasmonate-responsive gene expression and cuticle development via interactions with MEDIATOR COMPLEX SUBUNIT25 and transcription factor WIN1, respectively, while other interactions suggest evolutionary conservation of the Mediator kinase module.