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Adjustment of Host Cells for Accommodation of Symbiotic Bacteria: Vacuole Defunctionalization, HOPS Suppression, and TIP1g Retargeting in Medicago
- Gavrin, Aleksandr, Kaiser, Brent N., Geiger, Dietmar, Tyerman, Stephen D., Wen, Zhengyu, Bisseling, Ton, Fedorova, Elena E.
- The plant cell 2014 v.26 no.9 pp. 3809-3822
- Medicago, aquaporins, genes, legumes, microsymbionts, nitrogen fixation, root nodules, tonoplast, vacuoles
- The accommodation of thousands of nitrogen-fixing rhizobia in legume root nodules requires changes in functionality of the vacuoles of infected cells. Suppression of HOPS tethering complex genes and tonoplast aquaporin retargeting to symbiosomes is part of the underlying mechanism. Defunctionalization of host vacuoles contributes to the expansion and maintenance of intracellular rhizobia.