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Genome-Wide Analysis of Alternative Splicing in Zea mays: Landscape and Genetic Regulation
- Thatcher, Shawn R., Zhou, Wengang, Leonard, April, Wang, Bing-Bing, Beatty, Mary, Zastrow-Hayes, Gina, Zhao, Xiangyu, Baumgarten, Andy, Li, Bailin
- The plant cell 2014 v.26 no.9 pp. 3472-3487
- Zea mays, alternative splicing, corn, genes, loci, proteins
- This work examines alternative splicing (AS) of pre-mRNA in maize, revealing thousands of new isoforms from intron-containing genes, some of which encode entirely different proteins from their closest known isoforms. Analysis of these isoforms and identification of genomic loci that regulate AS highlight the important role that AS plays in tissue identity and genotypic variation in maize.