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Application of Antibody Titers against Bovine Viral Diarrhea Virus (BVDV) as a Measure to Detect Herds with Cattle Persistently Infected with BVDV
- Houe, H., Baker, J. C., Maes, R. K., Ruegg, P. L., Lloyd, J. W.
- infection, dairy cattle, Bovine viral diarrhea virus, dairy herds, detection, vaccination, live vaccines, antibodies, young animals, screening, Michigan
- Based on the distribution of antibody titers against bovine viral diarrhea virus (BVDV) in 10 Michigan dairy herds, it was calculated that screening of 5 young stock for BVDV antibody titer could be used to distinguish herds with persistently infected (PI) animals from herds without such animals. The herds were selected to represent 3 different herd categories: A, herds without use of vaccination and without PI animals (5 herds); B, herds with use of killed vaccine but no PI animals (2 herds); C, herds with use of killed vaccine and presence of PI animals (3 herds). The animals were described as having high antibody titers (≥ 128) or low antibody titers (≤ 64). For animals from 9 to 18 months of age, the probability of obtaining at least 3 animals with high titers among a screening sample of 5 animals was calculated as < 0.001 for all herds in category A, < 0.01 for the 2 herds in category B, and > 0.99 for all herds in category C. Thus, among herds in this study, by categorizing 9-1 &month-old animals as having high titers (> 128) or low titers (< 64), herds with PI cattle could be distinguished from other herds by testing only 5 animals.