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Comparison of bacteriostatic and bactericidal activity of 13 essential oils against strains with varying sensitivity to antibiotics

Author:
Mayaud, L., Carricajo, A., Zhiri, A., Aubert, G.
Source:
Letters in applied microbiology 2008 v.47 no.3 pp. 167-173
ISSN:
0266-8254
Subject:
Cinnamomum verum, Citrus sinensis, Cymbopogon citratus, Cymbopogon martinii, Eucalyptus globulus, Lavandula angustifolia, Melaleuca alternifolia, Origanum compactum, Pseudomonas aeruginosa, Syzygium aromaticum, Trachyspermum ammi, agar, aldehydes, antibacterial properties, antibiotic resistance, antibiotics, bacteria, bark, cross infection, essential oils, hydrocarbons, leaves, minimum inhibitory concentration, phenols
Abstract:
To compare the bacteriostatic and bactericidal activity of 13 chemotyped essential oils (EO) on 65 bacteria with varying sensitivity to antibiotics. Fifty-five bacterial strains were tested with two methods used for evaluation of antimicrobial activity (CLSI recommendations): the agar dilution method and the time-killing curve method. EO containing aldehydes (Cinnamomum verum bark and Cymbopogon citratus), phenols (Origanum compactum, Trachyspermum ammi, Thymus satureioides, Eugenia caryophyllus and Cinnamomum verum leaf) showed the highest antimicrobial activity with minimum inhibitory concentration (MIC) <2% (v/v) against all strains except Pseudomonas aeruginosa. Alcohol-based EO (Melaleuca alternifolia, Cymbopogon martinii and Lavandula angustifolia) exhibited varying degrees of activity depending on Gram status. EO containing 1·8-cineole and hydrocarbons (Eucalyptus globulus, Melaleuca cajeputii and Citrus sinensis) had MIC₉₀% >= 10% (v/v). Against P. aeruginosa, only C. verum bark and O. compactum presented MIC Cinnamomum verum bark had the highest antimicrobial activity, particularly against resistant strains. Bacteriostatic and bactericidal activity of EO on nosocomial antibiotic-resistant strains.
Agid:
2085664