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A Carotenoid Algal Preparation Containing Phytoene and Phytofluene Inhibited LDL Oxidation In Vitro

Author:
Shaish, Aviv, Harari, Ayelet, Kamari, Yehuda, Soudant, Etienne, Harats, Dror, Ben-Amotz, Ami
Source:
Plant foods for human nutrition 2008 v.63 no.2 pp. 83-86
ISSN:
0921-9668
Subject:
Dunaliella bardawil, alpha-tocopherol, antioxidant activity, beta-carotene, humans, low density lipoprotein, oxidation, oxidative stress, tissues
Abstract:
The antioxidative effect of the carotenoids phytoene and phytofluene in biological systems has not yet been studied. We therefore sought to investigate the effect of these carotenoids, isolated from the alga Dunaliella bardawil, in a biological system and used the in vitro low density lipoprotein (LDL) oxidation method to assay their antioxidative effects. We found that similar to β-carotene and α-tocopherol, a carotenoid algal preparation containing phytoene and phytofluene inhibited LDL oxidation. These findings and the presence of phytoene and phytofluene in human tissues suggest that they can be part of the defense system against oxidative stress.
Agid:
2102103