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On the production of glycerol and lâalanine during the aerobic fermentation of glucose by trypanosomatids
- Cazzulo, Juan JosÃ©, Arauzo, Silvia, Franke de Cazzulo, Berta M., Cannata, JoaquÃn J.B.
- FEMS microbiology letters 1988 v.51 no.2â3 pp. 187-191
- Crithidia fasciculata, Leishmania mexicana, Trypanosoma cruzi, alanine, anaerobic conditions, ethanol, fermentation, glucose, glycerol, succinic acid
- Glucose consumption and catabolite production by thick suspensions of Trypanosoma cruzi, Leishmania mexicana and Crithidia fasciculata were similar under aerobic and anaerobic conditions, indicating lack of Pasteur effect. Succinate was the main product for L. mexicana and C. fasciculata; the latter also produced similar amounts of ethanol. T. cruzi produced succinate and lâalanine to a similar extent. lâAlanine was also a major product of L. mexicana, but was neither produced, nor consumed, by C. fasciculata. Small amounts of glycerol were produced by L. mexicana and C. fasciculata, but not by T. cruzi, which had no detectable NADâdependent snâglycerolâ3âphosphate dehydrogenase activity.