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Postnatal behavioral consequences of antenatal intermittent hypoxia experienced during early organogenesis in mature rats

Author:
Trofimova, L. K., Graf, A. V., Maslova, M. V., Dunaeva, T. Yu., Maklakova, A. S., Sokolova, N. A.
Source:
Biology bulletin of the Russian Academy of Sciences 2010 v.37 no.1 pp. 44-48
ISSN:
1062-3590
Subject:
anxiety, hypoxia, males, organogenesis, rats
Abstract:
This study analyses the spontaneous behavior and anxiety-phobic status of mature rats that were subjected to antenatal intermittent hypoxia during the early stages of organogenesis. Antenatal intermittent hypoxia caused a decrease of motor activity as well as an enhanced anxiety level in rats of both sexes, while males appeared to be more sensitive to hypoxic influence. The effects of single antenatal intermittent hypoxia were more expressed than those of double exposure.
Agid:
2231588