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Molecular Characterization of Ovine Zygomycosis in Central Western Brazil
- de Paula, Daphine Ariadne Jesus, de Oliveira Filho, João Xavier, da Silva, Maria Cristina, Colodel, Edson Moleta, Broetto, Leonardo, Pinto, Paulo Marcos, Schrank, Augusto, Nakazato, Luciano, Dutra, Valéria
- sheep, sheep diseases, Conidiobolus, animal pathogenic fungi, mycoses, microbial genetics, polymerase chain reaction, strain differences, flocks, signs and symptoms (animals and humans), clinical examination, histopathology, ribosomal DNA, Brazil
- Zygomycosis is an important granulomatous disease that affects humans and animals, particularly sheep in tropical regions. Rhinofacial and nasopharyngeal zygomycosis were described in sheep in association with Conidiobolus spp. The present study characterized 5 samples of Conidiobolus isolated from 3 herds with clinical disease in Mato Grosso State, Brazil. The clinical and pathological findings were similar to nasopharyngeal zygomycosis. Based on morphological features, isolates were classified as Conidiobolus spp., and molecular phylogenetic analyses based on 18S ribosomal DNA grouped all isolates in a Conidiobolus lamprauges cluster. The current report describes the molecular characterization of ovine nasopharyngeal zygomycosis associated with C. lamprauges.