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Truncated Internalin A and Asymptomatic Listeria monocytogenes Carriage: In Vivo Investigation by Allelic Exchange

Author:
Olier, Mai̊wenn, Garmyn, Dominique, Rousseaux, Sandrine, Lemaître, Jean-Paul, Piveteau, Pascal, Guzzo, Jean
Source:
Infection and immunity 2005 v.73 no.1 pp. 644-648
ISSN:
0019-9567
Subject:
Listeria monocytogenes, chickens, virulence
Abstract:
Allelic exchange of the region coding for the C terminus of InlA between one epidemic (with an 80-kDa InlA) and one asymptomatic (with a 47-kDa InlA) carriage Listeria monocytogenes strain confirmed the need for this region for internalin entry in vitro. Interestingly, restoration of internalin A functionality did not result in full virulence in chicken embryo assays.
Agid:
252800