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Novel Antiinsectan Oxalicine Alkaloids from Two Undescribed Fungicolous Penicillium spp
- Zhang,Y., Li, C., Swenson, D.C., Gloer, J.B., Wicklow, D.T., Dowd, P.F.
- Organic letters 2003 v.5 no.5 pp. 773
- X-ray diffraction, Penicillium, alkaloids, chemical structure, nuclear magnetic resonance spectroscopy, insecticidal properties, Spodoptera frugiperda
- 15-Deoxyoxalicine B (1) and decaturins A (2) and B (3) have been isolated from Penicillium decaturense and Penicillium thiersii, two previously undescribed species obtained as colonists of wood-decay fungi. The structures were determined by 2D NMR experiments and/or single-crystal X-ray diffraction analysis. These compounds are members of a rare structural class, and decaturins A and B feature a new polycyclic ring system. Decaturin B (3) exhibited potent antiinsectan activity against the fall armyworm (Spodoptera frugiperda).