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New anthraquinone dimer from the root bark of Cassia artemisioides (Gaudich. Ex. DC) Randell
- Zaman, Khair, Khan, Mohammad Rafiullah, Ali, Mumtaz, Maitland, Derek J.
- Journal of Asian natural products research 2011 v.13 no.1 pp. 62-67
- Senna (Fabaceae), anthraquinones, antioxidant activity, chemical constituents of plants, nuclear magnetic resonance spectroscopy, roots, spectral analysis
- The phytochemical investigation of the root bark of Cassia artemisioides (Gaudich. Ex. DC) Randell resulted in the isolation of one new anthraquinone 1,1′-dihydroxy-3,3′-dimethyl-8,8′-dimethoxy-6,6′-O-bianthraquinone (1) along with four known anthraquinones 1,6-dihydroxy-8-methoxy-3-methylanthraquinone (2), 1-hydroxy-8-methoxy-3-methylanthraquinone (3), 1,8-dihydroxy-6-methoxy-3-methylanthraquinone (4), and 1,6,8-trihydroxy-3-methylanthraquinone (5). The structures of the compounds were elucidated using spectroscopic techniques including 1D and 2D NMR. The compounds were evaluated for antioxidant activity. 1,6,8-Trihydroxy-3-methyl anthraquinone (5) showed good activity among the tested compounds.