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Hyperinakin, a new anti-inflammatory phloroglucinol derivative from Hypericum nakamurai
- Cheng, Yuan-Bin, Fazary, Ahmed Eid, Lin, Yu-Chi, Lo, I-Wen, Ong, Seow-Chin, Chen, Shun-Ying, Chien, Ching-Te, Lin, Yen-Jung, Lin, Wan-Wan, Shen, Ya-Ching
- Natural product research 2013 v.27 no.8 pp. 727-734
- Hypericum, anti-inflammatory activity, spectroscopy
- Phytochemical investigation of Hypericum nakamurai (Masamune) Robson has led to the isolation of three phloroglucinol derivatives 1–3. The structures of these compounds were determined by the analysis of their spectroscopic data (IR, mass and UV), and by the application of 1-D and 2-D-NMR techniques. Hyperinakin (1) is a new compound. The anti-inflammatory activities of compounds 1–3 were also tested and evaluated. A biogenetic pathway for compounds 1–3 was also proposed.