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Hyperinakin, a new anti-inflammatory phloroglucinol derivative from Hypericum nakamurai

Author:
Cheng, Yuan-Bin, Fazary, Ahmed Eid, Lin, Yu-Chi, Lo, I-Wen, Ong, Seow-Chin, Chen, Shun-Ying, Chien, Ching-Te, Lin, Yen-Jung, Lin, Wan-Wan, Shen, Ya-Ching
Source:
Natural product research 2013 v.27 no.8 pp. 727-734
ISSN:
1478-6427
Subject:
Hypericum, anti-inflammatory activity, spectroscopy
Abstract:
Phytochemical investigation of Hypericum nakamurai (Masamune) Robson has led to the isolation of three phloroglucinol derivatives 1–3. The structures of these compounds were determined by the analysis of their spectroscopic data (IR, mass and UV), and by the application of 1-D and 2-D-NMR techniques. Hyperinakin (1) is a new compound. The anti-inflammatory activities of compounds 1–3 were also tested and evaluated. A biogenetic pathway for compounds 1–3 was also proposed.
Agid:
260988