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Campylobacter jejuni Gene Expression in the Chick Cecum: Evidence for Adaptation to a Low-Oxygen Environment

Author:
Woodall, C. A., Jones, M. A., Barrow, P. A., Hinds, J., Marsden, G. L., Kelly, D. J., Dorrell, N., Wren, B. W., Maskell, D. J.
Source:
Infection and immunity 2005 v.73 no.8 pp. 5278-5285
ISSN:
0019-9567
Subject:
Campylobacter jejuni, biochemical pathways, cecum, chicks, electron transfer, gene expression, gene expression regulation, genes, physiological state, transcription (genetics)
Abstract:
Transcriptional profiling of Campylobacter jejuni during colonization of the chick cecum identified 59 genes that were differentially expressed in vivo compared with the genes in vitro. The data suggest that C. jejuni regulates electron transport and central metabolic pathways to alter its physiological state during establishment in the chick cecum.
Agid:
266556