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Temporal Distribution and Parasite Load Kinetics in Blood and Tissues during Neospora caninum Infection in Mice
- Collantes-Fernández, Esther, López-Pérez, Inmaculada, Álvarez-García, Gema, Ortega-Mora, Luis M.
- Infection and immunity 2006 v.74 no.4 pp. 2491-2494
- DNA, Neospora caninum, blood, brain, mice, parasite load, parasitemia, parasites
- The kinetics of Neospora caninum loads in mice inoculated with NC-Liv or NC-1 isolates were studied. The acute phase was characterized by parasitemia and the detection of parasite DNA in several organs, whereas during the chronic phase, the parasite was detected mainly in the brain. Mice infected with NC-Liv developed clinical signs, showing higher brain parasite burdens than NC-1-infected mice.