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A decreasing feeding profile for the optimization of ethanol production in a recombinant Escherichia coli fed-batch fermentation
- Saucedo, V.M., Karim, M.N.
- Biotechnology letters 1996 v.18 no.9 pp. 1055-1060
- Escherichia coli, batch fermentation, ethanol, ethanol production, microorganisms, plasmids
- A decreasing feed flowrate was used to optimize the ethanol volumetric productivity and was found to be optimal and equal to 1.8 g ethanol/h.L with a recombinant Escherichia coli with plasmid pLOI297. This productivity is more than double in previous reports. High substrate concentrations favor ethanol production when the microorganisms are in the exponential phase and when they are not inhibited.