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A bacterial seek-and-destroy system for foreign DNA

Author:
Vogel, Jörg
Source:
Science 2014 v.344 no.6187 pp. 972-973
ISSN:
0036-8075
Subject:
DNA, RNA, gene silencing, proteins
Abstract:
Argonaute proteins have emerged as the key effectors in virtually all eukaryotic small RNA–mediated gene silencing pathways (1). Central to all their activities is their association with the small guide RNAs that allow them to recognize through sequence complementarity, and in some cases also cleave, cellular transcripts.
Agid:
3128497