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Three new compounds isolated from the seeds of Vaccaria segetalis

Author:
Zhang, Yan-Ling, Jiang, Li-Long, Xiao, Tong-Shu, Chen, Shou-Qian, Li, You-Bin
Source:
Journal of Asian natural products research 2015 v.17 no.7 pp. 717-723
ISSN:
1477-2213
Subject:
Vaccaria hispanica subsp. hispanica, capsaicin, coagulation, glycosides, nuclear magnetic resonance spectroscopy, seeds
Abstract:
Two new capsaicin analogs, N -(3-methoxy-4-hydroxyphenethyl)-tetracosanamide (1) and N -(3,4-dihydroxyphenethyl)-tetracosanamide (2), along with one new flavonoidal glycoside pinnatifin E (3) were isolated from the ethanolic extract of the seeds of Vaccaria segetalis . Their structures were elucidated on the basis of spectroscopic methods including 1D, 2D NMR, MS, and other spectroscopic techniques, as well as by comparison with the relevant literatures. All compounds were evaluated for their coagulation Factor Xa inhibition activities.
Agid:
3407128