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Assessment of coagulation utilizing thromboelastometry in dogs undergoing orthopedic surgery
- Bruno, Barbara, Maurella, Cristiana, Falco, Sara, Tarducci, Alberto, Zanatta, Renato, Gianella, Paola, D'Angelo, Antonio, Piras, Lisa, Di Bella, Andrea, Borrelli, Antonio
- Journal of veterinary emergency and critical care 2015 v.25 no.3 pp. 358-363
- adults, blood, blood coagulation, citrates, coagulation, dogs, firmness, humans, orthopedics, patients, surgery
- OBJECTIVE: To evaluate blood coagulation using thromboelastometry in dogs following orthopedic surgery. DESIGN: Longitudinal observational study. SETTING: University veterinary teaching hospital. ANIMALS: Thirty‐four adult client‐owned dogs. MEASUREMENTS AND MAIN RESULTS: Dogs undergoing elective or emergency orthopedic surgery had whole blood collected before (T0), at 24 hours (T1), and 1 week (T2) after surgery. Whole blood from each dog was collected by jugular venipuncture using a 20‐Ga needle and minimum venous stasis. The blood was placed into tubes containing 3.8% trisodium citrate (1 part citrate: 9 parts blood) and rested at 37°C. Coagulation was evaluated by means of thromboelastometry using the in‐TEM, ex‐TEM, and fib‐TEM assays. Statistically significant increases (P < 0.05) in maximum clot firmness (MCF) from T0 to T1 in the in‐TEM and fib‐TEM profiles (both P = 0.0001), from T0 to T2 in the in‐TEM, ex‐TEM, and fib‐TEM profiles (P = 0.012, P = 0.037, and P = 0.0001, respectively), and from T1 to T2 in the fib‐TEM profile (P = 0.039) were noted. The α angle increased from T0 to T2 in the in‐TEM and ex‐TEM profiles (P = 0.019 and P = 0.036, respectively). All results were, however, within the institutional reference ranges. CONCLUSIONS: In this study, unlike the hypercoagulability observed in human orthopedic patients, a hypercoagulable state as measured by thromboelastometry did not develop in dogs following orthopedic surgery.