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Clavine alkaloid biosynthesis by the fungus Penicillium palitans Westling 1911 isolated from ancient permafrost deposits
- Kozlovsky, A. G., Zhelifonova, V. P., Antipova, T. V.
- Applied biochemistry and microbiology 2009 v.45 no.2 pp. 182-186
- Penicillium, alkaloids, biosynthesis, culture media, fungi, permafrost, tryptophan, zinc
- The relic strain of Penicillium palitans isolated from the ancient permafrost deposits produces clavine alkaloids such as festuclavine, fumigaclavine A, and fumigaclavine B. Alkaloid biosynthesis is concurrent with the growth. Tryptophan and zinc ion additives to the culture medium stimulate the synthesis of alkaloids.