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High-level aminoglycoside resistant enterococci isolated from swine

Author:
Jackson, C.R., Barrett, J.B., Ladely, S.R.
Source:
Epidemiology and infection 2005 v.133 no.2 pp. 367
Subject:
Enterococcus, animal pathogenic bacteria, antibiotic resistance, aminoglycosides, antimicrobial agents, swine, swine diseases, bacterial infections
Abstract:
Approximately 42% (187/444) of swine enterococci collected between the years 1999 and 2000 exhibited high-level resistance to gentamicin (MIC > or equal 500 micrograms/ml), kanamycin (MIC > or equal 500 micrograms/ml), or streptomycin (MIC > or equal 1000 micrograms/ml). Eight aminoglycoside resistance genes were detected using PCR, most frequently ant(6)-Ia and aac(6')-Ii from Enterococcus faecium. Twenty-four per cent (45/187) of total high-level aminoglycoside-resistant isolates and 26% (4/15) of isolates resistant to high levels of all three antimicrobials were negative for all genes tested. These data suggest that enterococci isolated from swine contain diverse and possibly unidentified aminoglycoside resistance genes.
Agid:
38113
Handle:
10113/38113